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Protein

Transcription factor iws1

Gene

iws1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

  • chromatin silencing at centromere Source: PomBase
  • chromatin silencing at telomere Source: PomBase
  • transcription elongation from RNA polymerase II promoter Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor iws1
Gene namesi
Name:iws1
ORF Names:SPBC19G7.16
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19G7.16.
PomBaseiSPBC19G7.16. iws1.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  • chromosome, centromeric region Source: GOC
  • chromosome, telomeric region Source: GOC
  • mitotic spindle Source: PomBase
  • nucleolus Source: PomBase
  • nucleus Source: PomBase
  • transcription elongation factor complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 428428Transcription factor iws1PRO_0000083363Add
BLAST

Proteomic databases

MaxQBiO42964.

Interactioni

Protein-protein interaction databases

BioGridi277244. 3 interactions.
MINTiMINT-4674318.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini243 – 32078TFIIS N-terminalPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili2 – 6564Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the IWS1 family.Curated
Contains 1 TFIIS N-terminal domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000001004.
InParanoidiO42964.
KOiK17498.
OMAiRPILNKS.
OrthoDBiEOG7N0CHQ.
PhylomeDBiO42964.

Family and domain databases

Gene3Di1.20.930.10. 1 hit.
InterProiIPR017923. TFIIS_N.
[Graphical view]
PfamiPF08711. Med26. 1 hit.
[Graphical view]
SUPFAMiSSF47676. SSF47676. 1 hit.
PROSITEiPS51319. TFIIS_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42964-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEEKAELE NMQVESEAKT SENDQTIDTK VDVADVTTHV DEDLDNKEEA
60 70 80 90 100
LDFSEDELSD LDENQFENFD ESKIGREAEE PTIYNLPTFK KKQEPNTIEE
110 120 130 140 150
NLEVPRKVRK EQKPRRRRGK RSSTVDALND ELNELGENEE EVLTEQKQLD
160 170 180 190 200
PTLAAKKELD LQMDAVLKPT RTKKRSNEDN LEQMADDEVL RLREQMRLAA
210 220 230 240 250
LRDAELNSEQ LPATEKLKML PLVDAVLRKT HLYDTILDNN VLDSVRMWLE
260 270 280 290 300
PLPDRSLPAL NIQRSLMDIL TKLPIQTEHL RESKIGRIVL FYTISKKPEP
310 320 330 340 350
FIKRIADNLV SEWSRPIIKR SANYRDRAVG VASFNPEVFQ TRRRRDLAAA
360 370 380 390 400
ESNDDAQASR TGRTVIPRSI DSRYQVAPRV RLNPTAMTIA GRMKPADTEQ
410 420
VRKLKAKMKA IRSKSSKKSG VSIEGRGL
Length:428
Mass (Da):49,114
Last modified:June 1, 1998 - v1
Checksum:i887A4DCE96F64E99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17070.1.
PIRiT39847.
RefSeqiNP_595982.1. NM_001021889.2.

Genome annotation databases

EnsemblFungiiSPBC19G7.16.1; SPBC19G7.16.1:pep; SPBC19G7.16.
GeneIDi2540721.
KEGGispo:SPBC19G7.16.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA17070.1.
PIRiT39847.
RefSeqiNP_595982.1. NM_001021889.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277244. 3 interactions.
MINTiMINT-4674318.

Proteomic databases

MaxQBiO42964.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC19G7.16.1; SPBC19G7.16.1:pep; SPBC19G7.16.
GeneIDi2540721.
KEGGispo:SPBC19G7.16.

Organism-specific databases

EuPathDBiFungiDB:SPBC19G7.16.
PomBaseiSPBC19G7.16. iws1.

Phylogenomic databases

HOGENOMiHOG000001004.
InParanoidiO42964.
KOiK17498.
OMAiRPILNKS.
OrthoDBiEOG7N0CHQ.
PhylomeDBiO42964.

Miscellaneous databases

PROiO42964.

Family and domain databases

Gene3Di1.20.930.10. 1 hit.
InterProiIPR017923. TFIIS_N.
[Graphical view]
PfamiPF08711. Med26. 1 hit.
[Graphical view]
SUPFAMiSSF47676. SSF47676. 1 hit.
PROSITEiPS51319. TFIIS_N. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiIWS1_SCHPO
AccessioniPrimary (citable) accession number: O42964
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: June 1, 1998
Last modified: June 8, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.