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Protein

Transcription factor iws1

Gene

iws1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).By similarity

GO - Biological processi

  • chromatin silencing at centromere Source: PomBase
  • chromatin silencing at telomere Source: PomBase
  • transcription elongation from RNA polymerase II promoter Source: PomBase

Keywordsi

Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor iws1
Gene namesi
Name:iws1
ORF Names:SPBC19G7.16
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19G7.16
PomBaseiSPBC19G7.16 iws1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000833631 – 428Transcription factor iws1Add BLAST428

Proteomic databases

MaxQBiO42964
PaxDbiO42964
PRIDEiO42964

PTM databases

iPTMnetiO42964

Interactioni

Protein-protein interaction databases

BioGridi277244, 3 interactors
STRINGi4896.SPBC19G7.16.1

Structurei

3D structure databases

SMRiO42964
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini243 – 320TFIIS N-terminalPROSITE-ProRule annotationAdd BLAST78

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili2 – 65Sequence analysisAdd BLAST64

Sequence similaritiesi

Belongs to the IWS1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000001004
InParanoidiO42964
KOiK17498
OMAiQMIKAAN
OrthoDBiEOG092C3BAH
PhylomeDBiO42964

Family and domain databases

Gene3Di1.20.930.10, 1 hit
InterProiView protein in InterPro
IPR035441 TFIIS/LEDGF_dom_sf
IPR017923 TFIIS_N
PfamiView protein in Pfam
PF08711 Med26, 1 hit
SUPFAMiSSF47676 SSF47676, 1 hit
PROSITEiView protein in PROSITE
PS51319 TFIIS_N, 1 hit

Sequencei

Sequence statusi: Complete.

O42964-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEEKAELE NMQVESEAKT SENDQTIDTK VDVADVTTHV DEDLDNKEEA
60 70 80 90 100
LDFSEDELSD LDENQFENFD ESKIGREAEE PTIYNLPTFK KKQEPNTIEE
110 120 130 140 150
NLEVPRKVRK EQKPRRRRGK RSSTVDALND ELNELGENEE EVLTEQKQLD
160 170 180 190 200
PTLAAKKELD LQMDAVLKPT RTKKRSNEDN LEQMADDEVL RLREQMRLAA
210 220 230 240 250
LRDAELNSEQ LPATEKLKML PLVDAVLRKT HLYDTILDNN VLDSVRMWLE
260 270 280 290 300
PLPDRSLPAL NIQRSLMDIL TKLPIQTEHL RESKIGRIVL FYTISKKPEP
310 320 330 340 350
FIKRIADNLV SEWSRPIIKR SANYRDRAVG VASFNPEVFQ TRRRRDLAAA
360 370 380 390 400
ESNDDAQASR TGRTVIPRSI DSRYQVAPRV RLNPTAMTIA GRMKPADTEQ
410 420
VRKLKAKMKA IRSKSSKKSG VSIEGRGL
Length:428
Mass (Da):49,114
Last modified:June 1, 1998 - v1
Checksum:i887A4DCE96F64E99
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA17070.1
PIRiT39847
RefSeqiNP_595982.1, NM_001021889.2

Genome annotation databases

EnsemblFungiiSPBC19G7.16.1; SPBC19G7.16.1:pep; SPBC19G7.16
GeneIDi2540721
KEGGispo:SPBC19G7.16

Similar proteinsi

Entry informationi

Entry nameiIWS1_SCHPO
AccessioniPrimary (citable) accession number: O42964
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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