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Protein

MADS-box transcription factor 1

Gene

mbx1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Acts as a transcriptional activator with a role in the regulation of mitosis. Regulates septation and the periodic transcription of cdc15.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processCell cycle, Cell division, Mitosis, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
MADS-box transcription factor 1
Gene namesi
Name:mbx1
ORF Names:SPBC19G7.06
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC19G7.06
PomBaseiSPBC19G7.06 mbx1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001994431 – 457MADS-box transcription factor 1Add BLAST457

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei372Phosphoserine1 Publication1

Post-translational modificationi

Phosphorylated. Occurs periodically during mitosis.2 Publications

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO42954
PaxDbiO42954
PRIDEiO42954

PTM databases

iPTMnetiO42954
SwissPalmiO42954

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi277168, 55 interactors
STRINGi4896.SPBC19G7.06.1

Structurei

3D structure databases

SMRiO42954
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 71MADS-boxPROSITE-ProRule annotationAdd BLAST61

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi206 – 212Poly-Ser7

Phylogenomic databases

InParanoidiO42954
OrthoDBiEOG092C1PUJ

Family and domain databases

CDDicd00266 MADS_SRF_like, 1 hit
Gene3Di3.40.1810.10, 1 hit
InterProiView protein in InterPro
IPR033897 MADS_SRF-like
IPR002100 TF_MADSbox
IPR036879 TF_MADSbox_sf
PfamiView protein in Pfam
PF00319 SRF-TF, 1 hit
PRINTSiPR00404 MADSDOMAIN
SMARTiView protein in SMART
SM00432 MADS, 1 hit
SUPFAMiSSF55455 SSF55455, 1 hit
PROSITEiView protein in PROSITE
PS00350 MADS_BOX_1, 1 hit
PS50066 MADS_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

O42954-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDINPPPSTA PSSPRRSIQR ISDAKNKALT FNRRRLGLIK KAHELSVLCD
60 70 80 90 100
AKVVVMIFDS KNACHVYSSE EPEEQRDALL QKFLNKDFVT VDPLRNINPN
110 120 130 140 150
IPSDESLHNW RPKDKRIASV TTYSAQPSNN CSSATDSEND FQSFTIKSST
160 170 180 190 200
TYHTTPTTAS ENKKIESITI PDHASVYNDL PLSPTVKHSF VSPVSGDYSD
210 220 230 240 250
SPLEPSSSSS FSVPPESLNP TLSFQHNDVP QTDNFIPFLT PKRQAYGQSS
260 270 280 290 300
SRADRSSVRR SQSFKNRRNG KPRISRLHTS HASIDGLTDF IQSPSSGYLD
310 320 330 340 350
PSSTPITPLD SAINQITPPF LPDNLGQENR GELYSHDNPT SMVYEHPKFD
360 370 380 390 400
ELPNGFIDTH ELNILSRSFT ASPNQILRES NMVNQDSFTD NPVDATWDAL
410 420 430 440 450
IGTTQIDLDL DYERSSIPSS TIPADQLKDG VPTNSVYRNN MVDHNLYPSL

NIERNAP
Length:457
Mass (Da):50,907
Last modified:September 22, 2009 - v2
Checksum:i23466BEE2DC2A3CC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA17060.2
PIRiT39837
RefSeqiNP_595972.2, NM_001021880.3

Genome annotation databases

EnsemblFungiiSPBC19G7.06.1; SPBC19G7.06.1:pep; SPBC19G7.06
KEGGispo:SPBC19G7.06

Entry informationi

Entry nameiMBX1_SCHPO
AccessioniPrimary (citable) accession number: O42954
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: September 22, 2009
Last modified: May 23, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names

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