Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O42887

- SPEB2_SCHPO

UniProt

O42887 - SPEB2_SCHPO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative agmatinase 2

Gene

SPBC8E4.03

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Agmatine + H2O = putrescine + urea.

Cofactori

Mn2+PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi206 – 2061Manganese 1PROSITE-ProRule annotation
Metal bindingi229 – 2291Manganese 1PROSITE-ProRule annotation
Metal bindingi229 – 2291Manganese 2PROSITE-ProRule annotation
Metal bindingi231 – 2311Manganese 2PROSITE-ProRule annotation
Metal bindingi233 – 2331Manganese 1PROSITE-ProRule annotation
Metal bindingi331 – 3311Manganese 1PROSITE-ProRule annotation
Metal bindingi331 – 3311Manganese 2PROSITE-ProRule annotation
Metal bindingi333 – 3331Manganese 2PROSITE-ProRule annotation

GO - Molecular functioni

  1. agmatinase activity Source: UniProtKB-EC
  2. manganese ion binding Source: PomBase

GO - Biological processi

  1. cellular amino acid metabolic process Source: PomBase
  2. urea metabolic process Source: PomBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiREACT_241380. Agmatine biosynthesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative agmatinase 2 (EC:3.5.3.11)
Alternative name(s):
Agmatine ureohydrolase 2
Short name:
AUH 2
Gene namesi
ORF Names:SPBC8E4.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome II

Organism-specific databases

PomBaseiSPBC8E4.03.

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: PomBase
  2. fungal-type vacuole Source: PomBase
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence AnalysisAdd
BLAST
Chaini23 – 413391Putative agmatinase 2PRO_0000002092Add
BLAST

Proteomic databases

MaxQBiO42887.

Interactioni

Protein-protein interaction databases

BioGridi277792. 19 interactions.
MINTiMINT-4673750.
STRINGi4896.SPBC8E4.03-1.

Structurei

3D structure databases

ProteinModelPortaliO42887.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0010.
HOGENOMiHOG000204320.
InParanoidiO42887.
KOiK01480.
OMAiCGPIHRI.
OrthoDBiEOG718KPD.
PhylomeDBiO42887.

Family and domain databases

Gene3Di3.40.800.10. 1 hit.
InterProiIPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERiPTHR11358. PTHR11358. 1 hit.
PfamiPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFiPIRSF036979. Arginase. 1 hit.
PRINTSiPR00116. ARGINASE.
PROSITEiPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O42887-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFTYQKIIQL ALLLSGVCGA LASIDTDSHL SPKVLEKLRP TENLAYEDDS
60 70 80 90 100
LDDDTWRSKR WEFDYQYSGI STFAHLPHVR CLVEQSEDFD IAIIGVPFDT
110 120 130 140 150
AVSHRPGARF GPKGIRSASS RQMAIRGFNP SLNVNPYESW AKILDCGDIP
160 170 180 190 200
VSSYDNQLAV RQMTEGYIDL LSRKATASPA SNNLKTAGLA KDGIFHPRLI
210 220 230 240 250
TLGGDHSIGL ASLRALGHFY GNVSVIHFDS HLDTWNPKRY YPSYWHSDRA
260 270 280 290 300
DFTHGTMFWM ASKEGLINNG TSIHAGLRTR LSGTDYYDYE EDNRVGFTFI
310 320 330 340 350
EAQEIDEIGV NGIVERIKQV VGDTLVYLSI DIDVVDPGLA PGTGTPETGG
360 370 380 390 400
WTTREMKSIL RKLDGHLNLV GAEVVEVSPP YDDRAESTSL AASDFIFEIL
410
SSMVKHPLYD VKK
Length:413
Mass (Da):45,902
Last modified:June 1, 1998 - v1
Checksum:i577EF7AF936E1346
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA16996.1.
PIRiT50379. T39168.
RefSeqiNP_596844.1. NM_001023866.2.

Genome annotation databases

EnsemblFungiiSPBC8E4.03.1; SPBC8E4.03.1:pep; SPBC8E4.03.
GeneIDi2541279.
KEGGispo:SPBC8E4.03.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAA16996.1 .
PIRi T50379. T39168.
RefSeqi NP_596844.1. NM_001023866.2.

3D structure databases

ProteinModelPortali O42887.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 277792. 19 interactions.
MINTi MINT-4673750.
STRINGi 4896.SPBC8E4.03-1.

Proteomic databases

MaxQBi O42887.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPBC8E4.03.1 ; SPBC8E4.03.1:pep ; SPBC8E4.03 .
GeneIDi 2541279.
KEGGi spo:SPBC8E4.03.

Organism-specific databases

PomBasei SPBC8E4.03.

Phylogenomic databases

eggNOGi COG0010.
HOGENOMi HOG000204320.
InParanoidi O42887.
KOi K01480.
OMAi CGPIHRI.
OrthoDBi EOG718KPD.
PhylomeDBi O42887.

Enzyme and pathway databases

Reactomei REACT_241380. Agmatine biosynthesis.

Miscellaneous databases

NextBioi 20802390.

Family and domain databases

Gene3Di 3.40.800.10. 1 hit.
InterProi IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view ]
PANTHERi PTHR11358. PTHR11358. 1 hit.
Pfami PF00491. Arginase. 1 hit.
[Graphical view ]
PIRSFi PIRSF036979. Arginase. 1 hit.
PRINTSi PR00116. ARGINASE.
PROSITEi PS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiSPEB2_SCHPO
AccessioniPrimary (citable) accession number: O42887
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: June 1, 1998
Last modified: November 26, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3