Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative agmatinase 2

Gene

SPBC8E4.03

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Agmatine + H2O = putrescine + urea.

Cofactori

Mn2+PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi206Manganese 1PROSITE-ProRule annotation1
Metal bindingi229Manganese 1PROSITE-ProRule annotation1
Metal bindingi229Manganese 2PROSITE-ProRule annotation1
Metal bindingi231Manganese 2PROSITE-ProRule annotation1
Metal bindingi233Manganese 1PROSITE-ProRule annotation1
Metal bindingi331Manganese 1PROSITE-ProRule annotation1
Metal bindingi331Manganese 2PROSITE-ProRule annotation1
Metal bindingi333Manganese 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-SPO-351143 Agmatine biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Putative agmatinase 2 (EC:3.5.3.11)
Alternative name(s):
Agmatine ureohydrolase 2
Short name:
AUH 2
Gene namesi
ORF Names:SPBC8E4.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC8E4.03
PomBaseiSPBC8E4.03

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000000209223 – 413Putative agmatinase 2Add BLAST391

Proteomic databases

MaxQBiO42887
PaxDbiO42887
PRIDEiO42887

Interactioni

Protein-protein interaction databases

BioGridi277792, 19 interactors
STRINGi4896.SPBC8E4.03.1

Structurei

3D structure databases

ProteinModelPortaliO42887
SMRiO42887
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000204320
InParanoidiO42887
KOiK01480
OMAiCIDAGFV
OrthoDBiEOG092C3B4E
PhylomeDBiO42887

Family and domain databases

InterProiView protein in InterPro
IPR006035 Ureohydrolase
IPR023696 Ureohydrolase_dom_sf
IPR020855 Ureohydrolase_Mn_BS
PfamiView protein in Pfam
PF00491 Arginase, 1 hit
PIRSFiPIRSF036979 Arginase, 1 hit
PRINTSiPR00116 ARGINASE
SUPFAMiSSF52768 SSF52768, 1 hit
PROSITEiView protein in PROSITE
PS01053 ARGINASE_1, 1 hit
PS51409 ARGINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O42887-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTYQKIIQL ALLLSGVCGA LASIDTDSHL SPKVLEKLRP TENLAYEDDS
60 70 80 90 100
LDDDTWRSKR WEFDYQYSGI STFAHLPHVR CLVEQSEDFD IAIIGVPFDT
110 120 130 140 150
AVSHRPGARF GPKGIRSASS RQMAIRGFNP SLNVNPYESW AKILDCGDIP
160 170 180 190 200
VSSYDNQLAV RQMTEGYIDL LSRKATASPA SNNLKTAGLA KDGIFHPRLI
210 220 230 240 250
TLGGDHSIGL ASLRALGHFY GNVSVIHFDS HLDTWNPKRY YPSYWHSDRA
260 270 280 290 300
DFTHGTMFWM ASKEGLINNG TSIHAGLRTR LSGTDYYDYE EDNRVGFTFI
310 320 330 340 350
EAQEIDEIGV NGIVERIKQV VGDTLVYLSI DIDVVDPGLA PGTGTPETGG
360 370 380 390 400
WTTREMKSIL RKLDGHLNLV GAEVVEVSPP YDDRAESTSL AASDFIFEIL
410
SSMVKHPLYD VKK
Length:413
Mass (Da):45,902
Last modified:June 1, 1998 - v1
Checksum:i577EF7AF936E1346
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA16996.1
PIRiT50379 T39168
RefSeqiNP_596844.1, NM_001023866.2

Genome annotation databases

EnsemblFungiiSPBC8E4.03.1; SPBC8E4.03.1:pep; SPBC8E4.03
GeneIDi2541279
KEGGispo:SPBC8E4.03

Similar proteinsi

Entry informationi

Entry nameiSPEB2_SCHPO
AccessioniPrimary (citable) accession number: O42887
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health