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O42887 (SPEB2_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative agmatinase 2

EC=3.5.3.11
Alternative name(s):
Agmatine ureohydrolase 2
Short name=AUH 2
Gene names
ORF Names:SPBC8E4.03
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces

Protein attributes

Sequence length413 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Agmatine + H2O = putrescine + urea.

Cofactor

Manganese Potential.

Sequence similarities

Belongs to the arginase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 413391Putative agmatinase 2
PRO_0000002092

Sites

Metal binding2061Manganese 1 By similarity
Metal binding2291Manganese 1 By similarity
Metal binding2291Manganese 2 By similarity
Metal binding2311Manganese 2 By similarity
Metal binding2331Manganese 1 By similarity
Metal binding3311Manganese 1 By similarity
Metal binding3311Manganese 2 By similarity
Metal binding3331Manganese 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
O42887 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 577EF7AF936E1346

FASTA41345,902
        10         20         30         40         50         60 
MFTYQKIIQL ALLLSGVCGA LASIDTDSHL SPKVLEKLRP TENLAYEDDS LDDDTWRSKR 

        70         80         90        100        110        120 
WEFDYQYSGI STFAHLPHVR CLVEQSEDFD IAIIGVPFDT AVSHRPGARF GPKGIRSASS 

       130        140        150        160        170        180 
RQMAIRGFNP SLNVNPYESW AKILDCGDIP VSSYDNQLAV RQMTEGYIDL LSRKATASPA 

       190        200        210        220        230        240 
SNNLKTAGLA KDGIFHPRLI TLGGDHSIGL ASLRALGHFY GNVSVIHFDS HLDTWNPKRY 

       250        260        270        280        290        300 
YPSYWHSDRA DFTHGTMFWM ASKEGLINNG TSIHAGLRTR LSGTDYYDYE EDNRVGFTFI 

       310        320        330        340        350        360 
EAQEIDEIGV NGIVERIKQV VGDTLVYLSI DIDVVDPGLA PGTGTPETGG WTTREMKSIL 

       370        380        390        400        410 
RKLDGHLNLV GAEVVEVSPP YDDRAESTSL AASDFIFEIL SSMVKHPLYD VKK 

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU329671 Genomic DNA. Translation: CAA16996.1.
PIRT39168. T50379.
RefSeqNP_596844.1. NM_001023866.2.

3D structure databases

ProteinModelPortalO42887.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid277792. 18 interactions.
MINTMINT-4673750.
STRING4896.SPBC8E4.03-1.

Proteomic databases

MaxQBO42887.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC8E4.03.1; SPBC8E4.03.1:pep; SPBC8E4.03.
GeneID2541279.
KEGGspo:SPBC8E4.03.

Organism-specific databases

PomBaseSPBC8E4.03.

Phylogenomic databases

eggNOGCOG0010.
HOGENOMHOG000204320.
KOK01480.
OMACGPIHRI.
OrthoDBEOG718KPD.
PhylomeDBO42887.

Family and domain databases

Gene3D3.40.800.10. 1 hit.
InterProIPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERPTHR11358. PTHR11358. 1 hit.
PfamPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFPIRSF036979. Arginase. 1 hit.
PRINTSPR00116. ARGINASE.
PROSITEPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20802390.

Entry information

Entry nameSPEB2_SCHPO
AccessionPrimary (citable) accession number: O42887
Entry history
Integrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: June 1, 1998
Last modified: May 14, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names