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Protein

Putative invertase

Gene

SPAC8E11.01c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei18 – 181PROSITE-ProRule annotation
Binding sitei34 – 341SubstrateBy similarity
Binding sitei202 – 2021SubstrateBy similarity
Binding sitei288 – 2881SubstrateBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH32. Glycoside Hydrolase Family 32.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative invertase (EC:3.2.1.26)
Alternative name(s):
Beta-fructofuranosidase
Saccharase
Gene namesi
ORF Names:SPAC8E11.01c, SPAC959.01
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

PomBaseiSPAC8E11.01c.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nucleus Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 508508Putative invertasePRO_0000169868Add
BLAST

Proteomic databases

MaxQBiO42878.

Interactioni

Protein-protein interaction databases

BioGridi279155. 8 interactions.
MINTiMINT-4673708.

Structurei

3D structure databases

ProteinModelPortaliO42878.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni15 – 184Substrate bindingBy similarity
Regioni75 – 762Substrate bindingBy similarity
Regioni149 – 1502Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the glycosyl hydrolase 32 family.Curated

Phylogenomic databases

HOGENOMiHOG000181424.
InParanoidiO42878.
KOiK01193.
OMAiAHANDEN.
OrthoDBiEOG77M8ZG.

Family and domain databases

Gene3Di2.115.10.20. 1 hit.
2.60.120.560. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001362. Glyco_hydro_32.
IPR018053. Glyco_hydro_32_AS.
IPR013189. Glyco_hydro_32_C.
IPR013148. Glyco_hydro_32_N.
IPR023296. Glyco_hydro_beta-prop.
[Graphical view]
PfamiPF00251. Glyco_hydro_32N. 1 hit.
[Graphical view]
SMARTiSM00640. Glyco_32. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF75005. SSF75005. 1 hit.
PROSITEiPS00609. GLYCOSYL_HYDROL_F32. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42878-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVRPCIHFT PPEGFMNDPN GLVYSNGKWH LFFQWNPTGN QAGNQHWGHA
60 70 80 90 100
VSKNLYKWKL LPTALAPGDD HGLMFSGSAV IDKTNSSGFF ESGFFSRKSV
110 120 130 140 150
DPEERIVLIY TTHYDNRETQ NIAYSLDGGI TFIKYKKNPI LDIKESQFRD
160 170 180 190 200
PKVFWHEESR AWIMVVVLAQ KYKVLFYHSL NLRDWVKLSE FGSAGVLGYQ
210 220 230 240 250
YECPDFVRLP IEGTDEFRWV LIVSINPGSS INGGSMVQYF IGDFDGQTFT
260 270 280 290 300
PIDSASRILD CGHDCYATQT FGNAPDGRVI SISWASNWNY TNDVPMRMKH
310 320 330 340 350
RGMFTIPREL TLCYTHLNQE TRGLVLRQRP VNLHHLYYPD SLPAPLLLNR
360 370 380 390 400
VCEFPTVWTS ATVFYLAVSI PKSIVLESPM EFLCLTWSTT PDVETSKEYF
410 420 430 440 450
ELGYRFHDGA VYVERGVCSS SWKYPLYPER CTSSVPPSSY EDNYILEIEA
460 470 480 490 500
VVDHSIIEVY LQGGIMCLTN AYYFKGDEPL QYYYLRVPTG ASLAKSGMQP

LLNNRPHS
Length:508
Mass (Da):58,054
Last modified:February 22, 2012 - v3
Checksum:iBC81B3F546294734
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA17022.2.
PIRiT39155.
RefSeqiNP_594168.2. NM_001019592.2.

Genome annotation databases

EnsemblFungiiSPAC8E11.01c.1; SPAC8E11.01c.1:pep; SPAC8E11.01c.
GeneIDi2542702.
KEGGispo:SPAC8E11.01c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAA17022.2.
PIRiT39155.
RefSeqiNP_594168.2. NM_001019592.2.

3D structure databases

ProteinModelPortaliO42878.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279155. 8 interactions.
MINTiMINT-4673708.

Protein family/group databases

CAZyiGH32. Glycoside Hydrolase Family 32.

Proteomic databases

MaxQBiO42878.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC8E11.01c.1; SPAC8E11.01c.1:pep; SPAC8E11.01c.
GeneIDi2542702.
KEGGispo:SPAC8E11.01c.

Organism-specific databases

PomBaseiSPAC8E11.01c.

Phylogenomic databases

HOGENOMiHOG000181424.
InParanoidiO42878.
KOiK01193.
OMAiAHANDEN.
OrthoDBiEOG77M8ZG.

Miscellaneous databases

NextBioi20803750.
PROiO42878.

Family and domain databases

Gene3Di2.115.10.20. 1 hit.
2.60.120.560. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001362. Glyco_hydro_32.
IPR018053. Glyco_hydro_32_AS.
IPR013189. Glyco_hydro_32_C.
IPR013148. Glyco_hydro_32_N.
IPR023296. Glyco_hydro_beta-prop.
[Graphical view]
PfamiPF00251. Glyco_hydro_32N. 1 hit.
[Graphical view]
SMARTiSM00640. Glyco_32. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF75005. SSF75005. 1 hit.
PROSITEiPS00609. GLYCOSYL_HYDROL_F32. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiINVX_SCHPO
AccessioniPrimary (citable) accession number: O42878
Secondary accession number(s): Q9P4X5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: February 22, 2012
Last modified: May 11, 2016
This is version 92 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.