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Protein

Set1 complex component swd1

Gene

swd1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The Set1 complex specifically methylates 'Lys-4' of histone H3.1 Publication

GO - Biological processi

  • heterochromatin assembly involved in chromatin silencing Source: PomBase
  • histone H3-K4 methylation Source: PomBase

Enzyme and pathway databases

ReactomeiR-SPO-3214841 PKMTs methylate histone lysines
R-SPO-8951664 Neddylation

Names & Taxonomyi

Protein namesi
Recommended name:
Set1 complex component swd1
Short name:
Set1C component swd1
Alternative name(s):
COMPASS component swd1
Complex proteins associated with set1 protein swd1
Gene namesi
Name:swd1
ORF Names:SPAC23H3.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC23H3.05c
PomBaseiSPAC23H3.05c swd1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000512501 – 398Set1 complex component swd1Add BLAST398

Proteomic databases

MaxQBiO42858
PaxDbiO42858
PRIDEiO42858

PTM databases

iPTMnetiO42858
SwissPalmiO42858

Interactioni

Subunit structurei

Component of the Set1 complex composed of ash2, sdc1, set1, shg1, spp1, swd1, swd2 and swd3.

Protein-protein interaction databases

BioGridi278270, 280 interactors
ELMiO42858
STRINGi4896.SPAC23H3.05c.1

Structurei

3D structure databases

ProteinModelPortaliO42858
SMRiO42858
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati22 – 61WD 1Add BLAST40
Repeati64 – 103WD 2Add BLAST40
Repeati162 – 202WD 3Add BLAST41
Repeati247 – 295WD 4Add BLAST49
Repeati296 – 336WD 5Add BLAST41

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000204856
InParanoidiO42858
KOiK14961
OMAiFRMPILF
OrthoDBiEOG092C2ZQC
PhylomeDBiO42858

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR037850 RBBP5/Swd1
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PANTHERiPTHR44040 PTHR44040, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 2 hits
SMARTiView protein in SMART
SM00320 WD40, 5 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

O42858-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLELLDPFS IPDYPEALTT TLKHGHATSI RFSTNGYHLA SGLVNGSVVI
60 70 80 90 100
WDLSTFSVSR VLTGHTRAIQ SVCWSSCDRF LLTASRDWKC ILWDLRDGSI
110 120 130 140 150
VYQVVLSAPV WSASLHPHKI NTFVASLLDE SPQLIIVDDG IPKHKYLPTN
160 170 180 190 200
PDIDENYSDR RNRSKHVTLV SFFHPSGEYI LSGTSKGWFH VIDASTTKIR
210 220 230 240 250
SSHRITSQSI KQIRLSFCKR FLIFNSTDRV IRTVSIQDLD NPEVEHKFQD
260 270 280 290 300
VVNRLQWNSC GFSQTGEFVF ATTYQMAHAI YVWERGMGSL VKILEGPKEE
310 320 330 340 350
LVDVDWHPVF PCVASVGLDS GSIYIWAVEQ KESWSAFAPD FQELEENIEY
360 370 380 390
EEPEDEFDIH DETGKSEEEE YFTSVVKILP HDSSAEQPFV MPPTLSSS
Length:398
Mass (Da):45,184
Last modified:May 1, 2000 - v2
Checksum:i1EAFB611790AA5D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAB16241.2
PIRiT38298
RefSeqiNP_593795.1, NM_001019224.2

Genome annotation databases

EnsemblFungiiSPAC23H3.05c.1; SPAC23H3.05c.1:pep; SPAC23H3.05c
GeneIDi2541776
KEGGispo:SPAC23H3.05c

Similar proteinsi

Entry informationi

Entry nameiSWD1_SCHPO
AccessioniPrimary (citable) accession number: O42858
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: May 1, 2000
Last modified: June 20, 2018
This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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