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Protein

Set1 complex component swd1

Gene

swd1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

The Set1 complex specifically methylates 'Lys-4' of histone H3.1 Publication

GO - Biological processi

  • heterochromatin assembly involved in chromatin silencing Source: PomBase
  • histone H3-K4 methylation Source: PomBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Set1 complex component swd1
Short name:
Set1C component swd1
Alternative name(s):
COMPASS component swd1
Complex proteins associated with set1 protein swd1
Gene namesi
Name:swd1
ORF Names:SPAC23H3.05c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC23H3.05c.
PomBaseiSPAC23H3.05c. swd1.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: PomBase
  • nuclear chromatin Source: PomBase
  • nucleus Source: PomBase
  • Set1C/COMPASS complex Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398Set1 complex component swd1PRO_0000051250Add
BLAST

Proteomic databases

MaxQBiO42858.

PTM databases

SwissPalmiO42858.

Interactioni

Subunit structurei

Component of the Set1 complex composed of ash2, sdc1, set1, shg1, spp1, swd1, swd2 and swd3.

Protein-protein interaction databases

BioGridi278270. 280 interactions.
MINTiMINT-4673566.

Structurei

3D structure databases

ProteinModelPortaliO42858.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati22 – 6140WD 1Add
BLAST
Repeati64 – 10340WD 2Add
BLAST
Repeati162 – 20241WD 3Add
BLAST
Repeati247 – 29549WD 4Add
BLAST
Repeati296 – 33641WD 5Add
BLAST

Sequence similaritiesi

Contains 5 WD repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000204856.
InParanoidiO42858.
KOiK14961.
OMAiEQGVIEW.
OrthoDBiEOG092C2ZQC.
PhylomeDBiO42858.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42858-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLELLDPFS IPDYPEALTT TLKHGHATSI RFSTNGYHLA SGLVNGSVVI
60 70 80 90 100
WDLSTFSVSR VLTGHTRAIQ SVCWSSCDRF LLTASRDWKC ILWDLRDGSI
110 120 130 140 150
VYQVVLSAPV WSASLHPHKI NTFVASLLDE SPQLIIVDDG IPKHKYLPTN
160 170 180 190 200
PDIDENYSDR RNRSKHVTLV SFFHPSGEYI LSGTSKGWFH VIDASTTKIR
210 220 230 240 250
SSHRITSQSI KQIRLSFCKR FLIFNSTDRV IRTVSIQDLD NPEVEHKFQD
260 270 280 290 300
VVNRLQWNSC GFSQTGEFVF ATTYQMAHAI YVWERGMGSL VKILEGPKEE
310 320 330 340 350
LVDVDWHPVF PCVASVGLDS GSIYIWAVEQ KESWSAFAPD FQELEENIEY
360 370 380 390
EEPEDEFDIH DETGKSEEEE YFTSVVKILP HDSSAEQPFV MPPTLSSS
Length:398
Mass (Da):45,184
Last modified:May 1, 2000 - v2
Checksum:i1EAFB611790AA5D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB16241.2.
PIRiT38298.
RefSeqiNP_593795.1. NM_001019224.2.

Genome annotation databases

EnsemblFungiiSPAC23H3.05c.1; SPAC23H3.05c.1:pep; SPAC23H3.05c.
GeneIDi2541776.
KEGGispo:SPAC23H3.05c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB16241.2.
PIRiT38298.
RefSeqiNP_593795.1. NM_001019224.2.

3D structure databases

ProteinModelPortaliO42858.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278270. 280 interactions.
MINTiMINT-4673566.

PTM databases

SwissPalmiO42858.

Proteomic databases

MaxQBiO42858.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC23H3.05c.1; SPAC23H3.05c.1:pep; SPAC23H3.05c.
GeneIDi2541776.
KEGGispo:SPAC23H3.05c.

Organism-specific databases

EuPathDBiFungiDB:SPAC23H3.05c.
PomBaseiSPAC23H3.05c. swd1.

Phylogenomic databases

HOGENOMiHOG000204856.
InParanoidiO42858.
KOiK14961.
OMAiEQGVIEW.
OrthoDBiEOG092C2ZQC.
PhylomeDBiO42858.

Miscellaneous databases

PROiO42858.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00400. WD40. 2 hits.
[Graphical view]
SMARTiSM00320. WD40. 5 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
PROSITEiPS00678. WD_REPEATS_1. 2 hits.
PS50082. WD_REPEATS_2. 2 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSWD1_SCHPO
AccessioniPrimary (citable) accession number: O42858
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 2002
Last sequence update: May 1, 2000
Last modified: September 7, 2016
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.