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Protein

Putative RNA polymerase II subunit B1 CTD phosphatase rtr1

Gene

SPAC23A1.16c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi83ZincPROSITE-ProRule annotation1
Metal bindingi88ZincPROSITE-ProRule annotation1
Metal bindingi115ZincPROSITE-ProRule annotation1
Metal bindingi119ZincPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri60 – 139RTR1-typePROSITE-ProRule annotationAdd BLAST80

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protein phosphatase
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase rtr1 (EC:3.1.3.16)
Alternative name(s):
RNA polymerase II-associated protein 2 homolog rtr1
Gene namesi
ORF Names:SPAC23A1.16c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC23A1.16c
PomBaseiSPAC23A1.16c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003172101 – 197Putative RNA polymerase II subunit B1 CTD phosphatase rtr1Add BLAST197

Proteomic databases

MaxQBiO42853
PaxDbiO42853
PRIDEiO42853

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi278488, 1 interactor
STRINGi4896.SPAC23A1.16c.1

Structurei

3D structure databases

SMRiO42853
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RPAP2 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri60 – 139RTR1-typePROSITE-ProRule annotationAdd BLAST80

Keywords - Domaini

Zinc-finger

Phylogenomic databases

InParanoidiO42853
KOiK20827
OrthoDBiEOG092C3XCU
PhylomeDBiO42853

Family and domain databases

Gene3Di1.25.40.820, 1 hit
InterProiView protein in InterPro
IPR007308 Rtr1/RPAP2
IPR038534 Rtr1/RPAP2_sf
PfamiView protein in Pfam
PF04181 RPAP2_Rtr1, 1 hit
PROSITEiView protein in PROSITE
PS51479 ZF_RTR1, 1 hit

Sequencei

Sequence statusi: Complete.

O42853-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKKSILKKP KNAQSTQEKQ LITWSKSLID EARSRLQYDF FALEWIEKLV
60 70 80 90 100
DPVSLETLEE ARKYLRKSDY DQVVKERKLV NLCGYPVCPY EPKQQTRYKL
110 120 130 140 150
EDSGMKVYGG LNYYCSKDCF LKSCQYMVEL SDEPLWIRED AREAMKQHLD
160 170 180 190
PRQDEAFRKE LENKKIEDVR LLLQALPVGY KAKVGEIVEH PLANEQS
Length:197
Mass (Da):23,217
Last modified:June 1, 1998 - v1
Checksum:i8630B72C41F070E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAA16990.1
PIRiT38235
RefSeqiNP_594445.1, NM_001019874.2

Genome annotation databases

EnsemblFungiiSPAC23A1.16c.1; SPAC23A1.16c.1:pep; SPAC23A1.16c
GeneIDi2542005
KEGGispo:SPAC23A1.16c

Similar proteinsi

Entry informationi

Entry nameiRPAP2_SCHPO
AccessioniPrimary (citable) accession number: O42853
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health