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O42853

- RPAP2_SCHPO

UniProt

O42853 - RPAP2_SCHPO

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Protein
Putative RNA polymerase II subunit B1 CTD phosphatase rtr1
Gene
SPAC23A1.16c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation By similarity.

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri60 – 13980RTR1-type
Add
BLAST

GO - Molecular functioni

  1. CTD phosphatase activity Source: PomBase
  2. RNA polymerase core enzyme binding Source: PomBase
  3. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. dephosphorylation of RNA polymerase II C-terminal domain Source: PomBase
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative RNA polymerase II subunit B1 CTD phosphatase rtr1 (EC:3.1.3.16)
Alternative name(s):
RNA polymerase II-associated protein 2 homolog rtr1
Gene namesi
ORF Names:SPAC23A1.16c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
ProteomesiUP000002485: Chromosome I

Organism-specific databases

PomBaseiSPAC23A1.16c.

Subcellular locationi

Cytoplasm. Nucleus Inferred 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: PomBase
  2. cytosol Source: PomBase
  3. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 197197Putative RNA polymerase II subunit B1 CTD phosphatase rtr1
PRO_0000317210Add
BLAST

Proteomic databases

MaxQBiO42853.

Interactioni

Protein-protein interaction databases

MINTiMINT-4673535.
STRINGi4896.SPAC23A1.16c-1.

Family & Domainsi

Sequence similaritiesi

Belongs to the RPAP2 family.

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG241465.
OMAiWIREDAR.
OrthoDBiEOG7TXKVF.
PhylomeDBiO42853.

Family and domain databases

InterProiIPR007308. DUF408.
[Graphical view]
PfamiPF04181. RPAP2_Rtr1. 1 hit.
[Graphical view]
PROSITEiPS51479. ZF_RTR1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42853-1 [UniParc]FASTAAdd to Basket

« Hide

MNKKSILKKP KNAQSTQEKQ LITWSKSLID EARSRLQYDF FALEWIEKLV    50
DPVSLETLEE ARKYLRKSDY DQVVKERKLV NLCGYPVCPY EPKQQTRYKL 100
EDSGMKVYGG LNYYCSKDCF LKSCQYMVEL SDEPLWIRED AREAMKQHLD 150
PRQDEAFRKE LENKKIEDVR LLLQALPVGY KAKVGEIVEH PLANEQS 197
Length:197
Mass (Da):23,217
Last modified:June 1, 1998 - v1
Checksum:i8630B72C41F070E2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAA16990.1.
PIRiT38235.
RefSeqiNP_594445.1. NM_001019874.2.

Genome annotation databases

EnsemblFungiiSPAC23A1.16c.1; SPAC23A1.16c.1:pep; SPAC23A1.16c.
GeneIDi2542005.
KEGGispo:SPAC23A1.16c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU329670 Genomic DNA. Translation: CAA16990.1 .
PIRi T38235.
RefSeqi NP_594445.1. NM_001019874.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

MINTi MINT-4673535.
STRINGi 4896.SPAC23A1.16c-1.

Proteomic databases

MaxQBi O42853.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii SPAC23A1.16c.1 ; SPAC23A1.16c.1:pep ; SPAC23A1.16c .
GeneIDi 2542005.
KEGGi spo:SPAC23A1.16c.

Organism-specific databases

PomBasei SPAC23A1.16c.

Phylogenomic databases

eggNOGi NOG241465.
OMAi WIREDAR.
OrthoDBi EOG7TXKVF.
PhylomeDBi O42853.

Miscellaneous databases

NextBioi 20803085.
PROi O42853.

Family and domain databases

InterProi IPR007308. DUF408.
[Graphical view ]
Pfami PF04181. RPAP2_Rtr1. 1 hit.
[Graphical view ]
PROSITEi PS51479. ZF_RTR1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
    Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
    Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiRPAP2_SCHPO
AccessioniPrimary (citable) accession number: O42853
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 1, 1998
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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