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O42831

- YA075_YEAST

UniProt

O42831 - YA075_YEAST

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Protein
Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W
Gene
YAR075W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5 - Protein uncertaini

Functioni

GO - Molecular functioni

  1. catalytic activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. oxidation-reduction process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W
Gene namesi
Ordered Locus Names:YAR075W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome I

Organism-specific databases

SGDiS000002145. YAR075W.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 157157Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W
PRO_0000248413Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriO42831.

Interactioni

Protein-protein interaction databases

IntActiO42831. 1 interaction.
MINTiMINT-2491807.
STRINGi4932.YAR075W.

Structurei

3D structure databases

ProteinModelPortaliO42831.
SMRiO42831. Positions 6-138.

Family & Domainsi

Sequence similaritiesi

Belongs to the IMPDH/GMPR family.

Phylogenomic databases

HOGENOMiHOG000083425.
OMAiFKNIGHI.
OrthoDBiEOG793BHK.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR001093. IMP_DH_GMPRt.
[Graphical view]
PfamiPF00478. IMPDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42831-1 [UniParc]FASTAAdd to Basket

« Hide

MVVFKNIGHI ITKALALGSS TVMMGGMLAG TTESPGEYLY QDGKRLKAYR    50
GMGSIDAMQK TGTKGNASTS RYFSESDSVL VAQGVSGAVV DKGSIKKFIP 100
YLYNGLQHSC QDIGCRSLTL LKENVQSGKV RFEFRTASAQ LEGGVNNLHS 150
YEKRLHN 157
Length:157
Mass (Da):17,003
Last modified:June 1, 1998 - v1
Checksum:i90F3FCF03C244FCF
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L28920 Genomic DNA. Translation: AAC09511.1.
AY692623 Genomic DNA. Translation: AAT92642.1.
BK006935 Genomic DNA. No translation available.
PIRiS78078.

Genome annotation databases

EnsemblFungiiYAR075W; YAR075W; YAR075W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L28920 Genomic DNA. Translation: AAC09511.1 .
AY692623 Genomic DNA. Translation: AAT92642.1 .
BK006935 Genomic DNA. No translation available.
PIRi S78078.

3D structure databases

ProteinModelPortali O42831.
SMRi O42831. Positions 6-138.
ModBasei Search...

Protein-protein interaction databases

IntActi O42831. 1 interaction.
MINTi MINT-2491807.
STRINGi 4932.YAR075W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YAR075W ; YAR075W ; YAR075W .

Organism-specific databases

SGDi S000002145. YAR075W.

Phylogenomic databases

HOGENOMi HOG000083425.
OMAi FKNIGHI.
OrthoDBi EOG793BHK.

Gene expression databases

Genevestigatori O42831.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR001093. IMP_DH_GMPRt.
[Graphical view ]
Pfami PF00478. IMPDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 52 Kbp CDC15-FLO1-PHO11-YAR074 region."
    Bussey H., Keng T., Storms R.K., Vo D., Zhong W., Fortin N., Barton A.B., Kaback D.B., Clark M.W.
    Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204511 / S288c / AB972.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast."
    Hyle J.W., Shaw R.J., Reines D.
    J. Biol. Chem. 278:28470-28478(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION AS PSEUDOGENE.

Entry informationi

Entry nameiYA075_YEAST
AccessioniPrimary (citable) accession number: O42831
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: June 1, 1998
Last modified: May 14, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. In strain S288c, this gene has a frameshift compared to the other IMD alleles, producing 2 ORFs YAR073W and YAR075W.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome I
    Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

External Data

Dasty 3

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