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O42831 (YA075_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W
Gene names
Ordered Locus Names:YAR075W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length157 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Sequence similarities

Belongs to the IMPDH/GMPR family.

Caution

Could be the product of a pseudogene. In strain S288c, this gene has a frameshift compared to the other IMD alleles, producing 2 ORFs YAR073W and YAR075W.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processoxidation-reduction process

Inferred from electronic annotation. Source: InterPro

   Molecular_functioncatalytic activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 157157Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W
PRO_0000248413

Sequences

Sequence LengthMass (Da)Tools
O42831 [UniParc].

Last modified June 1, 1998. Version 1.
Checksum: 90F3FCF03C244FCF

FASTA15717,003
        10         20         30         40         50         60 
MVVFKNIGHI ITKALALGSS TVMMGGMLAG TTESPGEYLY QDGKRLKAYR GMGSIDAMQK 

        70         80         90        100        110        120 
TGTKGNASTS RYFSESDSVL VAQGVSGAVV DKGSIKKFIP YLYNGLQHSC QDIGCRSLTL 

       130        140        150 
LKENVQSGKV RFEFRTASAQ LEGGVNNLHS YEKRLHN 

« Hide

References

« Hide 'large scale' references
[1]"Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 52 Kbp CDC15-FLO1-PHO11-YAR074 region."
Bussey H., Keng T., Storms R.K., Vo D., Zhong W., Fortin N., Barton A.B., Kaback D.B., Clark M.W.
Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"The nucleotide sequence of chromosome I from Saccharomyces cerevisiae."
Bussey H., Kaback D.B., Zhong W.-W., Vo D.H., Clark M.W., Fortin N., Hall J., Ouellette B.F.F., Keng T., Barton A.B., Su Y., Davies C.J., Storms R.K.
Proc. Natl. Acad. Sci. U.S.A. 92:3809-3813(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[5]"Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast."
Hyle J.W., Shaw R.J., Reines D.
J. Biol. Chem. 278:28470-28478(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION AS PSEUDOGENE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L28920 Genomic DNA. Translation: AAC09511.1.
AY692623 Genomic DNA. Translation: AAT92642.1.
BK006935 Genomic DNA. No translation available.
PIRS78078.

3D structure databases

ProteinModelPortalO42831.
SMRO42831. Positions 6-138.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActO42831. 1 interaction.
MINTMINT-2491807.
STRING4932.YAR075W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYAR075W; YAR075W; YAR075W.

Organism-specific databases

SGDS000002145. YAR075W.

Phylogenomic databases

HOGENOMHOG000083425.
OMAFKNIGHI.
OrthoDBEOG793BHK.

Gene expression databases

GenevestigatorO42831.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
InterProIPR013785. Aldolase_TIM.
IPR001093. IMP_DH_GMPRt.
[Graphical view]
PfamPF00478. IMPDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYA075_YEAST
AccessionPrimary (citable) accession number: O42831
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: June 1, 1998
Last modified: January 22, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome I

Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families