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O42831

- YA075_YEAST

UniProt

O42831 - YA075_YEAST

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Protein

Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W

Gene

YAR075W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 1 out of 5- Protein uncertaini

Functioni

GO - Molecular functioni

  1. catalytic activity Source: InterPro

GO - Biological processi

  1. oxidation-reduction process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_235398. Purine ribonucleoside monophosphate biosynthesis.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W
Gene namesi
Ordered Locus Names:YAR075W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome I

Organism-specific databases

SGDiS000002145. YAR075W.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 157157Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075WPRO_0000248413Add
BLAST

Expressioni

Gene expression databases

GenevestigatoriO42831.

Interactioni

Protein-protein interaction databases

IntActiO42831. 1 interaction.
MINTiMINT-2491807.
STRINGi4932.YAR075W.

Structurei

3D structure databases

ProteinModelPortaliO42831.
SMRiO42831. Positions 6-138.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IMPDH/GMPR family.Curated

Phylogenomic databases

HOGENOMiHOG000083425.
OMAiFKNIGHI.
OrthoDBiEOG793BHK.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR001093. IMP_DH_GMPRt.
[Graphical view]
PfamiPF00478. IMPDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42831-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVVFKNIGHI ITKALALGSS TVMMGGMLAG TTESPGEYLY QDGKRLKAYR
60 70 80 90 100
GMGSIDAMQK TGTKGNASTS RYFSESDSVL VAQGVSGAVV DKGSIKKFIP
110 120 130 140 150
YLYNGLQHSC QDIGCRSLTL LKENVQSGKV RFEFRTASAQ LEGGVNNLHS

YEKRLHN
Length:157
Mass (Da):17,003
Last modified:June 1, 1998 - v1
Checksum:i90F3FCF03C244FCF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28920 Genomic DNA. Translation: AAC09511.1.
AY692623 Genomic DNA. Translation: AAT92642.1.
BK006935 Genomic DNA. No translation available.
PIRiS78078.

Genome annotation databases

EnsemblFungiiYAR075W; YAR075W; YAR075W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L28920 Genomic DNA. Translation: AAC09511.1 .
AY692623 Genomic DNA. Translation: AAT92642.1 .
BK006935 Genomic DNA. No translation available.
PIRi S78078.

3D structure databases

ProteinModelPortali O42831.
SMRi O42831. Positions 6-138.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O42831. 1 interaction.
MINTi MINT-2491807.
STRINGi 4932.YAR075W.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YAR075W ; YAR075W ; YAR075W .

Organism-specific databases

SGDi S000002145. YAR075W.

Phylogenomic databases

HOGENOMi HOG000083425.
OMAi FKNIGHI.
OrthoDBi EOG793BHK.

Enzyme and pathway databases

Reactomei REACT_235398. Purine ribonucleoside monophosphate biosynthesis.

Gene expression databases

Genevestigatori O42831.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR001093. IMP_DH_GMPRt.
[Graphical view ]
Pfami PF00478. IMPDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 52 Kbp CDC15-FLO1-PHO11-YAR074 region."
    Bussey H., Keng T., Storms R.K., Vo D., Zhong W., Fortin N., Barton A.B., Kaback D.B., Clark M.W.
    Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204511 / S288c / AB972.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast."
    Hyle J.W., Shaw R.J., Reines D.
    J. Biol. Chem. 278:28470-28478(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION AS PSEUDOGENE.

Entry informationi

Entry nameiYA075_YEAST
AccessioniPrimary (citable) accession number: O42831
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: June 1, 1998
Last modified: November 26, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. In strain S288c, this gene has a frameshift compared to the other IMD alleles, producing 2 ORFs YAR073W and YAR075W.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome I
    Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

External Data

Dasty 3