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O42831

- YA075_YEAST

UniProt

O42831 - YA075_YEAST

Protein

Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W

Gene

YAR075W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 1 out of 5- Protein uncertaini
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Jun 1998)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. catalytic activity Source: InterPro

    GO - Biological processi

    1. oxidation-reduction process Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075W
    Gene namesi
    Ordered Locus Names:YAR075W
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome I

    Organism-specific databases

    SGDiS000002145. YAR075W.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 157157Putative inosine-5'-monophosphate dehydrogenase-like protein YAR075WPRO_0000248413Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriO42831.

    Interactioni

    Protein-protein interaction databases

    IntActiO42831. 1 interaction.
    MINTiMINT-2491807.
    STRINGi4932.YAR075W.

    Structurei

    3D structure databases

    ProteinModelPortaliO42831.
    SMRiO42831. Positions 6-138.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the IMPDH/GMPR family.Curated

    Phylogenomic databases

    HOGENOMiHOG000083425.
    OMAiFKNIGHI.
    OrthoDBiEOG793BHK.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR001093. IMP_DH_GMPRt.
    [Graphical view]
    PfamiPF00478. IMPDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O42831-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVVFKNIGHI ITKALALGSS TVMMGGMLAG TTESPGEYLY QDGKRLKAYR    50
    GMGSIDAMQK TGTKGNASTS RYFSESDSVL VAQGVSGAVV DKGSIKKFIP 100
    YLYNGLQHSC QDIGCRSLTL LKENVQSGKV RFEFRTASAQ LEGGVNNLHS 150
    YEKRLHN 157
    Length:157
    Mass (Da):17,003
    Last modified:June 1, 1998 - v1
    Checksum:i90F3FCF03C244FCF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L28920 Genomic DNA. Translation: AAC09511.1.
    AY692623 Genomic DNA. Translation: AAT92642.1.
    BK006935 Genomic DNA. No translation available.
    PIRiS78078.

    Genome annotation databases

    EnsemblFungiiYAR075W; YAR075W; YAR075W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L28920 Genomic DNA. Translation: AAC09511.1 .
    AY692623 Genomic DNA. Translation: AAT92642.1 .
    BK006935 Genomic DNA. No translation available.
    PIRi S78078.

    3D structure databases

    ProteinModelPortali O42831.
    SMRi O42831. Positions 6-138.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi O42831. 1 interaction.
    MINTi MINT-2491807.
    STRINGi 4932.YAR075W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YAR075W ; YAR075W ; YAR075W .

    Organism-specific databases

    SGDi S000002145. YAR075W.

    Phylogenomic databases

    HOGENOMi HOG000083425.
    OMAi FKNIGHI.
    OrthoDBi EOG793BHK.

    Gene expression databases

    Genevestigatori O42831.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR001093. IMP_DH_GMPRt.
    [Graphical view ]
    Pfami PF00478. IMPDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 52 Kbp CDC15-FLO1-PHO11-YAR074 region."
      Bussey H., Keng T., Storms R.K., Vo D., Zhong W., Fortin N., Barton A.B., Kaback D.B., Clark M.W.
      Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204511 / S288c / AB972.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    5. "Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast."
      Hyle J.W., Shaw R.J., Reines D.
      J. Biol. Chem. 278:28470-28478(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION AS PSEUDOGENE.

    Entry informationi

    Entry nameiYA075_YEAST
    AccessioniPrimary (citable) accession number: O42831
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 5, 2006
    Last sequence update: June 1, 1998
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Caution

    Could be the product of a pseudogene. In strain S288c, this gene has a frameshift compared to the other IMD alleles, producing 2 ORFs YAR073W and YAR075W.Curated

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome I
      Yeast (Saccharomyces cerevisiae) chromosome I: entries and gene names

    External Data

    Dasty 3