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Protein
Submitted name:

Odorant receptor

Gene

or111-5

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Keywords - Biological processi

OlfactionSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Submitted name:
Odorant receptorImported
Submitted name:
Odorant receptor 2.2Imported
Submitted name:
Odorant receptor, family D, subfamily 111, member 5Imported
Submitted name:
Olfactory receptor protein 2.2Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:or111-5Imported
Synonyms:OR 2.2Imported, OR111-5Imported, or2.2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 15

Organism-specific databases

ZFINiZDB-GENE-000329-14. or111-5.

Subcellular locationi

  • Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei33 – 5523HelicalSequence analysisAdd
BLAST
Transmembranei105 – 12723HelicalSequence analysisAdd
BLAST
Transmembranei148 – 17023HelicalSequence analysisAdd
BLAST
Transmembranei207 – 23226HelicalSequence analysisAdd
BLAST
Transmembranei252 – 27423HelicalSequence analysisAdd
BLAST
Transmembranei280 – 30122HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090840.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini48 – 298251G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410J8TS. Eukaryota.
ENOG4111AVE. LUCA.
GeneTreeiENSGT00840000129747.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
PhylomeDBiO42605.
TreeFamiTF334163.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42605-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLNASFNQ NISIVHPQYF FIIGLSGIPY SSYYYIFLFV IYFITIIGNS
60 70 80 90 100
LVLLLIALDR SLHSPKYIGV FNLALADIGE TNALIPNMVK TFLFDSQYIS
110 120 130 140 150
YNACLANMFF VFFFSSLQSV SLVIMSYDRL IAICLPLRYH SIVNNSSMIL
160 170 180 190 200
VSPAIWIFNS SMVALMVSLI TRISFCDSNV IQSYFCDHGP VYRLACNDFN
210 220 230 240 250
LNKSVGFVIT SLFLIAPMII IFLSYLVIFL ALSKITTWER RLKALKTCVS
260 270 280 290 300
HLLLVGVYFF PICFTYLAQL LLALTPNARV ISTSLAYVVP PMLNPIIYVL
310 320
NTAEIKNLLQ KMFSKRSAPV REDISK
Length:326
Mass (Da):36,877
Last modified:January 1, 1998 - v1
Checksum:iC747596705D2FD33
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845428 Genomic DNA. No translation available.
AF012749 mRNA. Translation: AAC60256.1.
AF012756 Genomic DNA. Translation: AAC60264.1.
AF112374 Genomic DNA. Translation: AAF27271.1.
BC162074 mRNA. Translation: AAI62074.1.
BC162085 mRNA. Translation: AAI62085.1.
DQ306097 Genomic DNA. Translation: ABC43338.1.
RefSeqiNP_571667.1. NM_131592.1.
UniGeneiDr.75770.

Genome annotation databases

EnsembliENSDART00000100068; ENSDARP00000090840; ENSDARG00000091791.
GeneIDi58115.
KEGGidre:58115.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL845428 Genomic DNA. No translation available.
AF012749 mRNA. Translation: AAC60256.1.
AF012756 Genomic DNA. Translation: AAC60264.1.
AF112374 Genomic DNA. Translation: AAF27271.1.
BC162074 mRNA. Translation: AAI62074.1.
BC162085 mRNA. Translation: AAI62085.1.
DQ306097 Genomic DNA. Translation: ABC43338.1.
RefSeqiNP_571667.1. NM_131592.1.
UniGeneiDr.75770.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090840.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000100068; ENSDARP00000090840; ENSDARG00000091791.
GeneIDi58115.
KEGGidre:58115.

Organism-specific databases

CTDi58115.
ZFINiZDB-GENE-000329-14. or111-5.

Phylogenomic databases

eggNOGiENOG410J8TS. Eukaryota.
ENOG4111AVE. LUCA.
GeneTreeiENSGT00840000129747.
HOGENOMiHOG000041363.
HOVERGENiHBG017625.
PhylomeDBiO42605.
TreeFamiTF334163.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Noncoordinate expression of odorant receptor genes tightly linked in the zebrafish genome."
    Barth A.L., Dugas J.C., Ngai J.
    Neuron 19:359-369(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ABImported.
    Tissue: OlfactoryImported.
  2. "Analysis and characterization of an odorant receptor gene cluster in the zebrafish genome."
    Dugas J.C., Ngai J.
    Genomics 71:53-65(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ABImported.
  3. "The odorant receptor repertoire of teleost fish."
    Alioto T.S., Ngai J.
    BMC Genomics 6:173-173(2006)
    Cited for: NUCLEOTIDE SEQUENCE.
  4. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  6. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiO42605_DANRE
AccessioniPrimary (citable) accession number: O42605
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.