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O42573 (O42573_XENLA) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Nedd4 protein EMBL CAA03915.1
Gene names
Name:nedd4 EMBL CAA03915.1
OrganismXenopus laevis (African clawed frog) EMBL CAA03915.1
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length971 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 C2 domain. RuleBase RU003412 SAAS SAAS008973

Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. SAAS SAAS000569

Ontologies

Keywords
   Biological processUbl conjugation pathway SAAS SAAS000569
   DomainRepeat SAAS SAAS008973
Gene Ontology (GO)
   Biological_processprotein ubiquitination

Inferred from electronic annotation. Source: GOC

   Cellular_componentintracellular

Inferred from electronic annotation. Source: InterPro

   Molecular_functionubiquitin-protein ligase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
O42573 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: F25E36DC71612E03

FASTA971111,960
        10         20         30         40         50         60 
MAAEPIYGLS EDDEESRILR VKIVSGTDLA KKDIFGASDP YVKLSLYVAD ENRELALVQT 

        70         80         90        100        110        120 
KTIKKTLNPK WNEEFFFRVH PTNHRLLFEV FDENRLTRDD FLGQVDVPLN HLPTEDPTME 

       130        140        150        160        170        180 
RPYTFKDFLL RPRSHKSRVK GFLRLKMAYL PKNGMQEEET NEQREESEQA WDVVDSNDSS 

       190        200        210        220        230        240 
SPHQQELPAP PMPPGWEEKV DNLGRTYYVN HNNKSTQWQR PSLIDVASES DNNIRYIQQE 

       250        260        270        280        290        300 
AHRVFRSRRH ISEDLEPEHL EGVGDMPEPW ETISEEMTLT ADTLNQSLPP PASPDSRATA 

       310        320        330        340        350        360 
MELSEELNRR LQISSDSNGE QFSSIIQREP STRLRSCSVT DGVPEQAHLS LPSTSTGRAR 

       370        380        390        400        410        420 
SSTVTGGEDS TPTVAYVHTT PGLPSGWEER KDAKGRTYYV NHNNRTTTWT RPIVQHAEDG 

       430        440        450        460        470        480 
AVGSTSNSSN HLSEPQIRRP RSLSSPTVTL SAPLEGTKDF PVRRAVKDTL SNPQSPQPSP 

       490        500        510        520        530        540 
YNSPKPQHKG AQSFLPPGWE MRIAPNGRPF FIDHNTKTTT WEDPRLKFPV HMRTKASLNP 

       550        560        570        580        590        600 
NDLGPLPPGW EERIHMDGRT FYIDHNTKIT QWEDPRLQNP AITGPAVPYS REFKQKYDYF 

       610        620        630        640        650        660 
RKKLKKPADI PNRFEMKLHR NNIFEESYRR IMSVKRPDVL KARLWIEFES EKGLDYGGVA 

       670        680        690        700        710        720 
REWFFLLSKE MFNPYYGLFE YSATDNYTLQ INPNSGLCNE DHLSYFTFIG RIAGLAVFHG 

       730        740        750        760        770        780 
KLLDGFFIRP FYKMMLGKQI TLKDMESVDS EYYNSLKWIL ENDPTELDLM FCIDEENFGQ 

       790        800        810        820        830        840 
TYQVDLKPNG SEMVVTNDNK REYIDLVIQW RFVNRVQKQM NAFLEGFTEL IAIDLIKIFD 

       850        860        870        880        890        900 
ENELELLMCG LGDVDVNDWR QHTLYKNGYC PNHPAVQWFW KAVLLMDAEK RIRLLQFVTG 

       910        920        930        940        950        960 
TSRVPMNGFA ELYGSNGPQL FTIEQWGSPD KLPRAHTCFN RLDLPPYDSF EDLREKLLMA 

       970 
VENAQGFEGV D

« Hide

References

[1]"Molecular cloning of Nedd4 from Xenopus laevis."
Rebhun J.F., Pratt J.H.
DNA Seq. 9:295-306(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ000085 mRNA. Translation: CAA03915.1.
UniGeneXl.206.

3D structure databases

HSSPHSSP built from PDB template 1I5H based on UniProtKB Q62940.
ProteinModelPortalO42573.
SMRO42573. Positions 3-151, 189-223, 380-414, 490-527, 536-584, 590-962.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG004134.

Family and domain databases

InterProIPR000008. C2_Ca-dep.
IPR008973. C2_Ca/lipid-bd_dom_CaLB.
IPR020477. C2_dom.
IPR018029. C2_membr_targeting.
IPR024928. E3_ub_ligase_SMURF1.
IPR000569. HECT.
IPR001202. WW_dom.
[Graphical view]
PfamPF00168. C2. 1 hit.
PF00632. HECT. 1 hit.
PF00397. WW. 4 hits.
[Graphical view]
PIRSFPIRSF001569. E3_ub_ligase_SMURF1. 1 hit.
PRINTSPR00360. C2DOMAIN.
SMARTSM00239. C2. 1 hit.
SM00119. HECTc. 1 hit.
SM00456. WW. 4 hits.
[Graphical view]
SUPFAMSSF49562. C2_CaLB. 1 hit.
SSF56204. HECT. 1 hit.
SSF51045. WW_Rsp5_WWP. 4 hits.
PROSITEPS50004. C2. 1 hit.
PS50237. HECT. 1 hit.
PS01159. WW_DOMAIN_1. 4 hits.
PS50020. WW_DOMAIN_2. 4 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameO42573_XENLA
AccessionPrimary (citable) accession number: O42573
Entry history
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info