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Protein

Homeobox protein Hox-A9a

Gene

hoxa9a

Organism
Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi216 – 27560HomeoboxPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental protein

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-A9a
Short name:
HoxA-9
Gene namesi
Name:hoxa9a
Synonyms:hoxa9
OrganismiTakifugu rubripes (Japanese pufferfish) (Fugu rubripes)
Taxonomic identifieri31033 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTakifugu
Proteomesi
  • UP000005226 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 283283Homeobox protein Hox-A9aPRO_0000200086Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000040839.

Structurei

3D structure databases

ProteinModelPortaliO42506.
SMRiO42506. Positions 204-279.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Abd-B homeobox family.Curated
Contains 1 homeobox DNA-binding domain.PROSITE-ProRule annotation

Keywords - Domaini

Homeobox

Phylogenomic databases

eggNOGiKOG0487. Eukaryota.
ENOG4111FJP. LUCA.
GeneTreeiENSGT00760000118834.
InParanoidiO42506.
OMAiNNPVSNW.
OrthoDBiEOG091G0IP5.
TreeFamiTF317819.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
IPR006711. Hox9_activation_N.
IPR017112. HXA9/HXB9/HXC9.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF04617. Hox9_act. 1 hit.
[Graphical view]
PIRSFiPIRSF037109. Homeobox_Hox9. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42506-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTSGTLTSY YVDSLILPEN EELSVPRYSA GPGHQHSRQP ASIGDPHSEL
60 70 80 90 100
GTCSFPSKPP VFGPSWSHVP AQFPGTVSSV YHHHYGHHQG PVGTETDGRY
110 120 130 140 150
QSWLLEPMSG SLPMAGLPTT HHYGIKPDGL GVRSGGALPG SHTALLLSDY
160 170 180 190 200
ANGTVATAPP VEKDAVSSHT GDGVDTEEKP GLDPSKSAVY ITFYLYRTYS
210 220 230 240 250
GDRDNPVSNW LHASATRKKR CPYTKHQILE LEKEFLFNTY LTRDRRYEVA
260 270 280
RLLNLTERQV KIWFQNRRMK MKKFNKDGAP KDD
Length:283
Mass (Da):31,410
Last modified:January 1, 1998 - v1
Checksum:iFDD3D052702BE36C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U92573 Genomic DNA. Translation: AAB68684.1.
DQ481663 Genomic DNA. Translation: ABF22379.1.

Genome annotation databases

EnsembliENSTRUT00000040981; ENSTRUP00000040839; ENSTRUG00000015974.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U92573 Genomic DNA. Translation: AAB68684.1.
DQ481663 Genomic DNA. Translation: ABF22379.1.

3D structure databases

ProteinModelPortaliO42506.
SMRiO42506. Positions 204-279.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi31033.ENSTRUP00000040839.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSTRUT00000040981; ENSTRUP00000040839; ENSTRUG00000015974.

Phylogenomic databases

eggNOGiKOG0487. Eukaryota.
ENOG4111FJP. LUCA.
GeneTreeiENSGT00760000118834.
InParanoidiO42506.
OMAiNNPVSNW.
OrthoDBiEOG091G0IP5.
TreeFamiTF317819.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
IPR006711. Hox9_activation_N.
IPR017112. HXA9/HXB9/HXC9.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF04617. Hox9_act. 1 hit.
[Graphical view]
PIRSFiPIRSF037109. Homeobox_Hox9. 1 hit.
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHXA9A_TAKRU
AccessioniPrimary (citable) accession number: O42506
Secondary accession number(s): Q1KL15
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Vertebrate homeotic Hox proteins
    Nomenclature of vertebrate homeotic Hox proteins and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.