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Protein
Submitted name:

Beta catenin

Gene

chBcat

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • cadherin binding Source: AgBase
  • extracellular matrix binding Source: AgBase
  • ligand-dependent nuclear receptor transcription coactivator activity Source: AgBase
  • protein C-terminus binding Source: UniProtKB
  • protein N-terminus binding Source: UniProtKB
  • sequence-specific DNA binding Source: AgBase
  • signal transducer activity Source: InterPro
  • transcription cofactor activity Source: AgBase
  • transcription regulatory region DNA binding Source: AgBase

GO - Biological processi

  • adherens junction assembly Source: InterPro
  • canonical Wnt signaling pathway Source: AgBase
  • cardiac epithelial to mesenchymal transition Source: AgBase
  • delamination Source: AgBase
  • dorsal/ventral pattern formation Source: AgBase
  • embryonic forelimb morphogenesis Source: AgBase
  • embryonic hindlimb morphogenesis Source: AgBase
  • limb morphogenesis Source: AgBase
  • negative regulation of cell adhesion mediated by integrin Source: AgBase
  • negative regulation of cell migration Source: AgBase
  • negative regulation of cell proliferation Source: AgBase
  • positive regulation of fibroblast growth factor production Source: AgBase
  • positive regulation of gene expression Source: AgBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Beta cateninImported
Gene namesi
Name:chBcatImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

  • adherens junction Source: AgBase
  • cytoplasm Source: AgBase
  • cytosol Source: AgBase
  • membrane Source: AgBase
  • nucleus Source: AgBase
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiO42486.
PRIDEiO42486.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
Calcoco1Q8CGU14EBI-972394,EBI-972374From a different organism.
CDH2P102885EBI-972394,EBI-985728
FERP165912EBI-972394,EBI-1380661From a different organism.
Lrrfip1Q3UZ392EBI-972394,EBI-2270972From a different organism.

GO - Molecular functioni

  • cadherin binding Source: AgBase
  • protein C-terminus binding Source: UniProtKB
  • protein N-terminus binding Source: UniProtKB

Protein-protein interaction databases

IntActiO42486. 5 interactors.
STRINGi9031.ENSGALP00000019402.

Structurei

3D structure databases

ProteinModelPortaliO42486.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4203. Eukaryota.
COG0035. LUCA.
HOGENOMiHOG000230958.
HOVERGENiHBG000919.
KOiK02105.
PhylomeDBiO42486.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view]
PfamiPF00514. Arm. 4 hits.
[Graphical view]
PRINTSiPR01869. BCATNINFAMLY.
SMARTiSM00185. ARM. 12 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42486-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATQADLMEL DMAMEPDRKA AVSHWQQQSY LDSGIHSGAT TTAPSLSGKG
60 70 80 90 100
NPEEEDVDTT QVLYEWEQGF SQSFTQEQVA DIDGQYAMTR AQRVLSAMFP
110 120 130 140 150
ETLDEGMQIP STQFDAAHPT NVQRLAEPSQ MLKHAVVNLI NYQDDAELAT
160 170 180 190 200
RAIPELTKLL NDEDQVVVNK AAVMVHQLSK KEASRHAIMR SPQMVSAIVR
210 220 230 240 250
TMQNTNDVET ARCTAGTLHN LSHHREGLLA IFKSGGIPAL VKMLGSPVDS
260 270 280 290 300
VLFYAITTLH NLLLHQEGAK MAVRLAGGLQ KMVALLNKTN VKFLAITTDC
310 320 330 340 350
LQILAYGNQE SKLIILASGG PQALVNIMRT YTYEKLLWTT SRVLKVLSVC
360 370 380 390 400
SSNKPAIVEA GGMQALGLHL TDPSQRLVQN CLWTLRNLSD AATKQEGMEG
410 420 430 440 450
LLGTLVQLLG SDDINVVTCA AGILSNLTCN NYKNKMMVCQ VGGIEALVRT
460 470 480 490 500
VLRAGDREDI TEPAICALRH LTSRHQEAEM AQNAVRLHYG LPVVVKLLHP
510 520 530 540 550
PSHWPLIKAT VGLIRNLALC PANHAPLREQ GAIPRLVQLL VRAHQDTQRR
560 570 580 590 600
TSMGGTQQQF VEGVRMEEIV EGCTGALHIL ARDVHNRIVI RGLNTIPLFV
610 620 630 640 650
QLLYSPIENI QRVAAGVLCE LAQDKEAAEA IEAEGGTAPL TELLHSRNEG
660 670 680 690 700
VATYAAAVLF RMSEDKPQDY KKRLSVELTS SLFRTEPMAW NETADLGLDI
710 720 730 740 750
GAQGEPLGYR PDDPSYRSFH SGGYGQDALG MDPMMEHEMG GHHPGADYPV
760 770 780
DGLPDLGHAQ DLMDGLPPGD SNQLAWFDTD L
Length:781
Mass (Da):85,439
Last modified:January 1, 1998 - v1
Checksum:i6D205D9A4DBAC562
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82964 mRNA. Translation: AAB80856.1.
RefSeqiNP_990412.1. NM_205081.1.
UniGeneiGga.4283.

Genome annotation databases

GeneIDi395964.
KEGGigga:395964.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82964 mRNA. Translation: AAB80856.1.
RefSeqiNP_990412.1. NM_205081.1.
UniGeneiGga.4283.

3D structure databases

ProteinModelPortaliO42486.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO42486. 5 interactors.
STRINGi9031.ENSGALP00000019402.

Proteomic databases

PaxDbiO42486.
PRIDEiO42486.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395964.
KEGGigga:395964.

Organism-specific databases

CTDi1499.

Phylogenomic databases

eggNOGiKOG4203. Eukaryota.
COG0035. LUCA.
HOGENOMiHOG000230958.
HOVERGENiHBG000919.
KOiK02105.
PhylomeDBiO42486.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view]
PfamiPF00514. Arm. 4 hits.
[Graphical view]
PRINTSiPR01869. BCATNINFAMLY.
SMARTiSM00185. ARM. 12 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 9 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO42486_CHICK
AccessioniPrimary (citable) accession number: O42486
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.