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Protein
Submitted name:

17-beta-hydroxysteroid dehydrogenase type IV

Gene

HSD17B4

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-GGA-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
R-GGA-2046106 alpha-linolenic acid (ALA) metabolism
R-GGA-389887 Beta-oxidation of pristanoyl-CoA
R-GGA-390247 Beta-oxidation of very long chain fatty acids
R-GGA-9033241 Peroxisomal protein import

Names & Taxonomyi

Protein namesi
Submitted name:
17-beta-hydroxysteroid dehydrogenase type IVImported
Submitted name:
Hydroxysteroid 17-beta dehydrogenase 4Imported
Gene namesi
Name:HSD17B4Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome Z

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSGALG00000002187

Structurei

3D structure databases

SMRiO42484
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini482 – 598MaoC-likeInterPro annotationAdd BLAST117
Domaini627 – 730SCP2InterPro annotationAdd BLAST104

Phylogenomic databases

GeneTreeiENSGT00530000062928
HOGENOMiHOG000170895
HOVERGENiHBG002174
KOiK12405
OMAiSRMTQTV
OrthoDBiEOG091G02S9

Family and domain databases

Gene3Di3.30.1050.10, 1 hit
InterProiView protein in InterPro
IPR029069 HotDog_dom_sf
IPR002539 MaoC_dom
IPR036291 NAD(P)-bd_dom_sf
IPR020904 Sc_DH/Rdtase_CS
IPR003033 SCP2_sterol-bd_dom
IPR036527 SCP2_sterol-bd_dom_sf
IPR002347 SDR_fam
PfamiView protein in Pfam
PF00106 adh_short, 1 hit
PF01575 MaoC_dehydratas, 1 hit
PF02036 SCP2, 1 hit
PRINTSiPR00081 GDHRDH
PR00080 SDRFAMILY
SUPFAMiSSF51735 SSF51735, 1 hit
SSF54637 SSF54637, 2 hits
SSF55718 SSF55718, 1 hit
PROSITEiView protein in PROSITE
PS00061 ADH_SHORT, 1 hit

Sequencei

Sequence statusi: Complete.

O42484-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAGLRFDGR VVLVTGAGGG LGRAYALAFA ERGASVVVND LGGDFKGYGK
60 70 80 90 100
SSSAADKVVS EIRANGGKAV PNYDSVEDGE KLVKSALEAF GRIDIVINNA
110 120 130 140 150
GILRDRSFVR ISDEDWDIIH RIHLRGSFLV TRAAWNHMKN QKFGRIIMTS
160 170 180 190 200
SAAGIYGNFG QANYSAAKLG LLGLSNTIAI EGRKYNIHCN TIAPTAGSRL
210 220 230 240 250
TQTVMPQDLI DAFKPEYVAP LVLWLCHETC MENGSLFEVG AGWIGKLRWE
260 270 280 290 300
RSLGAIVRGK DQPMTPEAVR DKWEKVCDFN NASKPRSIQE SISVLNDALS
310 320 330 340 350
QIESQGSISM NSTNSRSVVS SAVDTTSLVG RELTTKVYKY THLEPILYAL
360 370 380 390 400
GVGMSTKDPD HLKFLFEGSE EFCCLPTFGV IPAQTSMFDG VPSIPGLDMD
410 420 430 440 450
LAKMLHGEQY LELYKPLPTS GELRSVSTIA DLLDKGSGAV LLIDVNTYCG
460 470 480 490 500
KDLVCYNQFS LFFVGAGGFG GKRTSEKAKV TVNPPKRPPD AILSDVTTSD
510 520 530 540 550
QAALYRLSGD WNPLHLDPSF AALGGFQKPI LHGLCTFGFA ARNVLKQFAN
560 570 580 590 600
NDVTRFKAIK VRFAKPVFPG QTLQTEMWKE GNRIHFQTKV KETGDLAIAG
610 620 630 640 650
GYVDIVSALD KPSALEPTAG LQSDLVFEEI GRRIKEVGHE LVRKVNAVFQ
660 670 680 690 700
WDITKDGKTA VQWTIDLKNG SGSVYQGPAR SSADTTFTLS DQDFMDVVQK
710 720 730
KTNPQKAFFS GKLKVKGNIM LSQKLEMILK DYAKL
Length:735
Mass (Da):80,149
Last modified:January 1, 1998 - v1
Checksum:i6D24AD4C7CC5179D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC192621 Genomic DNA No translation available.
U77911 mRNA Translation: AAC60249.1
RefSeqiNP_990274.1, NM_204943.1
UniGeneiGga.3546

Genome annotation databases

EnsembliENSGALT00000003423; ENSGALP00000003418; ENSGALG00000002187
GeneIDi395785
KEGGigga:395785

Similar proteinsi

Entry informationi

Entry nameiO42484_CHICK
AccessioniPrimary (citable) accession number: O42484
Secondary accession number(s): E1BW32
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health