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Protein
Submitted name:

Spi-1/PU.1 transcription factor

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: InterPro
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Spi-1/PU.1 transcription factorImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000013176.

Structurei

3D structure databases

ProteinModelPortaliO42415.
SMRiO42415. Positions 156-244.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ETS family.UniRule annotation
Contains 1 ETS DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiNOG237824.
HOGENOMiHOG000095520.
HOVERGENiHBG002474.
KOiK09438.
PhylomeDBiO42415.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000418. Ets_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00178. Ets. 1 hit.
[Graphical view]
PRINTSiPR00454. ETSDOMAIN.
SMARTiSM00413. ETS. 1 hit.
[Graphical view]
PROSITEiPS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42415-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLQACKMEGF PLIPPPSEDM VSYESDLYRQ PHDYYQYLNS DGDSHGDHYW
60 70 80 90 100
EYHPHHVHSE FETFGDNHFT ELQSVQPPQL QQLYRHMEIE QMHVLDSAIP
110 120 130 140 150
TTHIGLTHQY SSPPQPSSDE EDIERQSPPL EVSDGETDGV DPGPGIMHGE
160 170 180 190 200
TGSKKKIRLY QFLLDLLRSG DMKDSIWWVD KEKGTFQFSS KHKEALAHRW
210 220 230 240 250
GIQKGNRKKM TYQKMARALR NYGKTGEVKK VKKKLTYQFS GEVMGRGVAD

RKHYPH
Length:256
Mass (Da):29,701
Last modified:January 1, 1998 - v1
Checksum:i774B6C918D4C6ABA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12225 mRNA. Translation: CAA72901.1.
RefSeqiNP_990354.1. NM_205023.1.
UniGeneiGga.1313.

Genome annotation databases

GeneIDi395879.
KEGGigga:395879.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y12225 mRNA. Translation: CAA72901.1.
RefSeqiNP_990354.1. NM_205023.1.
UniGeneiGga.1313.

3D structure databases

ProteinModelPortaliO42415.
SMRiO42415. Positions 156-244.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000013176.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395879.
KEGGigga:395879.

Organism-specific databases

CTDi6688.

Phylogenomic databases

eggNOGiNOG237824.
HOGENOMiHOG000095520.
HOVERGENiHBG002474.
KOiK09438.
PhylomeDBiO42415.

Miscellaneous databases

NextBioi20815946.
PROiO42415.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR000418. Ets_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00178. Ets. 1 hit.
[Graphical view]
PRINTSiPR00454. ETSDOMAIN.
SMARTiSM00413. ETS. 1 hit.
[Graphical view]
PROSITEiPS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Isolation and characterization of a chicken homologue of the Spi-1/PU.1 transcription factor."
    Kherrouche Z., Beuscart A., Huguet C., Flourens A., Moreau-Gachelin F., Stehelin D., Coll J.
    Oncogene 16:1357-1367(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: SpafasImported.

Entry informationi

Entry nameiO42415_CHICK
AccessioniPrimary (citable) accession number: O42415
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: February 4, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.