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Protein
Submitted name:

Bradykinin receptor B2

Gene

BDKRB2

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Enzyme and pathway databases

ReactomeiR-GGA-375276. Peptide ligand-binding receptors.
R-GGA-416476. G alpha (q) signalling events.
R-GGA-418594. G alpha (i) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Bradykinin receptor B2Imported
Submitted name:
Ornithokinin receptorImported
Gene namesi
Name:BDKRB2Imported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei58 – 79HelicalSequence analysisAdd BLAST22
Transmembranei91 – 110HelicalSequence analysisAdd BLAST20
Transmembranei130 – 148HelicalSequence analysisAdd BLAST19
Transmembranei169 – 190HelicalSequence analysisAdd BLAST22
Transmembranei220 – 241HelicalSequence analysisAdd BLAST22
Transmembranei261 – 279HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSGALG00000011080.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000018030.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 324G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST256

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410INT3. Eukaryota.
ENOG41117RA. LUCA.
GeneTreeiENSGT00760000119055.
HOGENOMiHOG000010314.
HOVERGENiHBG103183.
OMAiENSMGTL.
OrthoDBiEOG091G0AAK.
TreeFamiTF330024.

Family and domain databases

InterProiView protein in InterPro
IPR001504. Brdyknn_2_rcpt.
IPR000496. Brdyknn_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00425. BRADYKININR.
PR00994. BRADYKINNB2R.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O42402-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITITTENVT QLYNVTATQE FTISPAEFHN NSSVHQMDEY KCINPDTWKW
60 70 80 90 100
LQTFQPGFLW IIFILGTIEN AFVLIVLYFH KSRCSVAEIY LANMAFADLM
110 120 130 140 150
LVCSLPFWAI NISNGFQWPF GLFLCKAVNT INYMNSYSSI YFLTLVSIDR
160 170 180 190 200
YLALVKTMSL GRMRRTACAK WNSLIIWMCA LLICSPTMVF RNLQYFKEYN
210 220 230 240 250
ITACSLDYPT PYWHPANNCL LNAVGFMIPL CIITYCTTQI IKALQSNKSQ
260 270 280 290 300
KLKLIQTERK ATLLVLAVLL LFVICWLPFQ ISTLIDTVCY LAGNLKCLED
310 320 330 340 350
INDIVTQMAI YCAFSNSCLN PILYVIVGKH FQKKAVELFK DLIPQRCRKS
360 370 380
ESVKIENSQD TLRTSISSEH LRKKSVLPLS Q
Length:381
Mass (Da):43,763
Last modified:January 1, 1998 - v1
Checksum:i850BC43B6DDDC16D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC161470 Genomic DNA. No translation available.
AJ001928 Genomic DNA. Translation: CAA05099.1.
RefSeqiNP_001026724.1. NM_001031553.1.
XP_015143039.1. XM_015287553.1.
XP_015143040.1. XM_015287554.1.
UniGeneiGga.32085.

Genome annotation databases

EnsembliENSGALT00000018052; ENSGALP00000018030; ENSGALG00000011080.
GeneIDi428906.

Similar proteinsi

Entry informationi

Entry nameiO42402_CHICK
AccessioniPrimary (citable) accession number: O42402
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 22, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported