Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

POU domain protein

Gene

pou2f1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi275 – 335HomeoboxPROSITE-ProRule annotationAdd BLAST61

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:pou2f1aImported
Synonyms:oct1Imported, pouII1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-185 pou2f1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO42276
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini176 – 250POU-specificInterPro annotationAdd BLAST75
Domaini273 – 334HomeoboxInterPro annotationAdd BLAST62

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG057016
KOiK09364
PhylomeDBiO42276

Family and domain databases

CDDicd00086 homeodomain, 1 hit
cd00093 HTH_XRE, 1 hit
InterProiView protein in InterPro
IPR001387 Cro/C1-type_HTH
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
IPR013847 POU
IPR000327 POU_dom
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF00157 Pou, 1 hit
PRINTSiPR00028 POUDOMAIN
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00352 POU, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS00035 POU_1, 1 hit
PS00465 POU_2, 1 hit
PS51179 POU_3, 1 hit

Sequencei

Sequence statusi: Complete.

O42276-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESAAQAQTN GVDAQKPSAG AASGAVGGVQ ALLPQLNLTP AQLLQTQLLA
60 70 80 90 100
AVQQSAGQQS STTGASISAS AATPITLSQP IQIASPQGLN LPQFVLVQPG
110 120 130 140 150
HSISTQIQPQ FILSPSAQGP TGLLQPQSLL TSLPQSQTTQ TSIALTTQEP
160 170 180 190 200
PRPGRSPPCQ APAAPTPKRV DGVCVEEAGD LEELEQFAKN FKQRRIKLGF
210 220 230 240 250
TQGDVGLAMG KLYGNDFSQT TISRFEALNL SFKNMCKLKP LLEKWLTDAE
260 270 280 290 300
NMSSDCVVSS ASEMSPGLSE SLNRRRKKRT SIETSIRIAL ERSFLEQSQK
310 320 330 340 350
PSSEEITLIA DQLSMEKEVV RVWFCNRRQK EKRINPPSSS AASPASAIKT
360 370 380 390 400
IYSTQTAAVS SGSNTLTVNP VVPLSSSGLS NLTLSGGALG HVTSNTPSVI
410 420 430 440 450
SMAPAIATPA PAVTSQTPSS SASAGKQEIR AATSSAATLT QGAGPLLVTG
460 470 480 490 500
AGLGGANLTT FATGLNPTII TPSQLAQGGA LLSLAPALGN TLSPALMNNN
510 520 530 540 550
ALATIQALAS GGAFPLTSID GNTSLLFANT SAANSTPSLV TTPFFLNPSG
560 570 580 590
LSLLPANFLS AGGAGGGALN LHLTSDVQQN LVATTTKGVA LASKAQ
Length:596
Mass (Da):61,094
Last modified:January 1, 1998 - v1
Checksum:i263322E2BAE91E27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030519 mRNA Translation: AAB84295.1
RefSeqiNP_571513.1, NM_131438.1
UniGeneiDr.569

Genome annotation databases

GeneIDi30715
KEGGidre:30715

Similar proteinsi

Entry informationi

Entry nameiO42276_DANRE
AccessioniPrimary (citable) accession number: O42276
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health