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Protein

POU domain protein

Gene

pou2f1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
POU domain proteinUniRule annotation
Gene namesi
Name:pou2f1aImported
Synonyms:oct1Imported, pouII1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-185. pou2f1a.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO42276.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini176 – 250POU-specificInterPro annotationAdd BLAST75
Domaini273 – 334Homeobox DNA-bindingInterPro annotationAdd BLAST62

Sequence similaritiesi

Belongs to the POU transcription factor family.UniRule annotationSAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG057016.
KOiK09364.
PhylomeDBiO42276.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR010982. Lambda_DNA-bd_dom.
IPR013847. POU.
IPR000327. POU_dom.
PfamiView protein in Pfam
PF00046. Homeobox. 1 hit.
PF00157. Pou. 1 hit.
PRINTSiPR00028. POUDOMAIN.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SM00352. POU. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF47413. SSF47413. 1 hit.
PROSITEiView protein in PROSITE
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00035. POU_1. 1 hit.
PS00465. POU_2. 1 hit.
PS51179. POU_3. 1 hit.

Sequencei

Sequence statusi: Complete.

O42276-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESAAQAQTN GVDAQKPSAG AASGAVGGVQ ALLPQLNLTP AQLLQTQLLA
60 70 80 90 100
AVQQSAGQQS STTGASISAS AATPITLSQP IQIASPQGLN LPQFVLVQPG
110 120 130 140 150
HSISTQIQPQ FILSPSAQGP TGLLQPQSLL TSLPQSQTTQ TSIALTTQEP
160 170 180 190 200
PRPGRSPPCQ APAAPTPKRV DGVCVEEAGD LEELEQFAKN FKQRRIKLGF
210 220 230 240 250
TQGDVGLAMG KLYGNDFSQT TISRFEALNL SFKNMCKLKP LLEKWLTDAE
260 270 280 290 300
NMSSDCVVSS ASEMSPGLSE SLNRRRKKRT SIETSIRIAL ERSFLEQSQK
310 320 330 340 350
PSSEEITLIA DQLSMEKEVV RVWFCNRRQK EKRINPPSSS AASPASAIKT
360 370 380 390 400
IYSTQTAAVS SGSNTLTVNP VVPLSSSGLS NLTLSGGALG HVTSNTPSVI
410 420 430 440 450
SMAPAIATPA PAVTSQTPSS SASAGKQEIR AATSSAATLT QGAGPLLVTG
460 470 480 490 500
AGLGGANLTT FATGLNPTII TPSQLAQGGA LLSLAPALGN TLSPALMNNN
510 520 530 540 550
ALATIQALAS GGAFPLTSID GNTSLLFANT SAANSTPSLV TTPFFLNPSG
560 570 580 590
LSLLPANFLS AGGAGGGALN LHLTSDVQQN LVATTTKGVA LASKAQ
Length:596
Mass (Da):61,094
Last modified:January 1, 1998 - v1
Checksum:i263322E2BAE91E27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF030519 mRNA. Translation: AAB84295.1.
RefSeqiNP_571513.1. NM_131438.1.
UniGeneiDr.569.

Genome annotation databases

GeneIDi30715.
KEGGidre:30715.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiO42276_DANRE
AccessioniPrimary (citable) accession number: O42276
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 5, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)