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Protein

Protein Wnt

Gene

wnt7b

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotation

Keywords - Biological processi

Wnt signaling pathwayUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:wnt7bImported
Synonyms:Xwnt7BImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-864808. wnt7b.

Subcellular locationi

  • Secretedextracellular spaceextracellular matrix UniRule annotationSAAS annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 3426HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Membrane, Secreted

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOVERGENiHBG001595.
KOiK00572.

Family and domain databases

InterProiIPR005817. Wnt.
IPR013300. Wnt7.
IPR018161. Wnt_CS.
[Graphical view]
PANTHERiPTHR12027. PTHR12027. 1 hit.
PfamiPF00110. wnt. 1 hit.
[Graphical view]
PRINTSiPR01891. WNT7PROTEIN.
PR01349. WNTPROTEIN.
SMARTiSM00097. WNT1. 1 hit.
[Graphical view]
PROSITEiPS00246. WNT1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42258-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHRHFRNWIF YVFLCFGIIY MKLGALSSVV ALGANIICNK IPGLAPRQRA
60 70 80 90 100
ICESRPDAII IIGEGAQMGI NECQYQFRYG RWNCSALGER TVFGQELRVG
110 120 130 140 150
SREAAFTYAI TAAGVAHAVT SACSQGNLSN CGCDREKQGY YNQEEGWKWG
160 170 180 190 200
GCSADIKYGI DFSRKFVDAR EIKKNARRLM NLHNNEAGRK VLEERMKLEC
210 220 230 240 250
KCHGVSGSCT TKTCWNTLPK FREIGFVLKE KYNDAVHVEV VRANRLRQPT
260 270 280 290 300
FLKIKKVRSY QKPMETDLVY IERSPNYCEE DSATGSVGTQ GRLCNRTSPY
310 320 330 340
TDGCDLMCCG RGYNTHQYTK VWQCNCKFHW CCFVKCNTCS ERTEVFTCK
Length:349
Mass (Da):39,741
Last modified:January 1, 1998 - v1
Checksum:i9196AA0B98058248
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF026894 mRNA. Translation: AAB82725.1.
BC169513 mRNA. Translation: AAI69513.1.
BC170343 mRNA. Translation: AAI70343.1.
RefSeqiNP_001084202.1. NM_001090733.1.
UniGeneiXl.229.

Genome annotation databases

GeneIDi399364.
KEGGixla:399364.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF026894 mRNA. Translation: AAB82725.1.
BC169513 mRNA. Translation: AAI69513.1.
BC170343 mRNA. Translation: AAI70343.1.
RefSeqiNP_001084202.1. NM_001090733.1.
UniGeneiXl.229.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi399364.
KEGGixla:399364.

Organism-specific databases

CTDi7477.
XenbaseiXB-GENE-864808. wnt7b.

Phylogenomic databases

HOVERGENiHBG001595.
KOiK00572.

Family and domain databases

InterProiIPR005817. Wnt.
IPR013300. Wnt7.
IPR018161. Wnt_CS.
[Graphical view]
PANTHERiPTHR12027. PTHR12027. 1 hit.
PfamiPF00110. wnt. 1 hit.
[Graphical view]
PRINTSiPR01891. WNT7PROTEIN.
PR01349. WNTPROTEIN.
SMARTiSM00097. WNT1. 1 hit.
[Graphical view]
PROSITEiPS00246. WNT1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Neural crest induction by Xwnt7B in Xenopus."
    Chang C., Hemmati-Brivanlou A.
    Dev. Biol. 194:129-134(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. NIH - Xenopus Gene Collection (XGC) project
    Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: OocytesImported.

Entry informationi

Entry nameiO42258_XENLA
AccessioniPrimary (citable) accession number: O42258
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.