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Protein
Submitted name:

Trypsinogen b2

Gene

TRYPB2

Organism
Petromyzon marinus (Sea lamprey)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotation

Protein family/group databases

MEROPSiS01.128.

Names & Taxonomyi

Protein namesi
Submitted name:
Trypsinogen b2Imported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:TRYPB2Imported
Synonyms:Pma.6031Imported
OrganismiPetromyzon marinus (Sea lamprey)Imported
Taxonomic identifieri7757 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataCyclostomataHyperoartiaPetromyzontiformesPetromyzontidaePetromyzon

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1313Sequence analysisAdd
BLAST
Chaini14 – 245232Sequence analysisPRO_5004158560Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7757.ENSPMAP00000004810.

Structurei

3D structure databases

ProteinModelPortaliO42160.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini22 – 243222Peptidase S1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase S1 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiCOG5640. LUCA.
KOG3627. Eukaryota.
GeneTreeiENSGT00760000118862.
HOVERGENiHBG013304.
OrthoDBiEOG75B84T.
TreeFamiTF331065.

Family and domain databases

InterProiIPR018114. Peptidase_S1_AS.
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

O42160-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GLIFALLVGT AAAAPYMYED HIVGGYECAA HSQPWQVSLN IGYHFCGGSL
60 70 80 90 100
ISSEWVVSAA HCYQTASRIS VRIGEHNIFV TEGTEQRIQA SKAIRHPQYN
110 120 130 140 150
SATIDNDIML IKLSSPATLN QYAQAIPLPS SCVGTGVMCT ISGWGETQTS
160 170 180 190 200
VGSPDVLMCV QAPVLSDTSC RNSYPGDITN NMICLGYLEG GKDSCQGDSG
210 220 230 240
GPVVCNGQLQ GIVSWGRGCA LPNYPGVYTK VCNYNSWIAS TMAAN
Length:245
Mass (Da):26,001
Last modified:January 1, 1998 - v1
Checksum:i9A932508B896C93E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF011901 mRNA. Translation: AAB69657.1.

Genome annotation databases

EnsembliENSPMAT00000004829; ENSPMAP00000004810; ENSPMAG00000004392.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF011901 mRNA. Translation: AAB69657.1.

3D structure databases

ProteinModelPortaliO42160.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7757.ENSPMAP00000004810.

Protein family/group databases

MEROPSiS01.128.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPMAT00000004829; ENSPMAP00000004810; ENSPMAG00000004392.

Phylogenomic databases

eggNOGiCOG5640. LUCA.
KOG3627. Eukaryota.
GeneTreeiENSGT00760000118862.
HOVERGENiHBG013304.
OrthoDBiEOG75B84T.
TreeFamiTF331065.

Family and domain databases

InterProiIPR018114. Peptidase_S1_AS.
IPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The Molecular Evolution of the Vertebrate Trypsinogens."
    Roach J.C.
    Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Ensembl
    Submitted (JUL-2013) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiO42160_PETMA
AccessioniPrimary (citable) accession number: O42160
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: December 9, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.