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Protein
Submitted name:

Vitellogenin receptor

Gene

vldlr

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Vitellogenin receptorImported
Gene namesi
Name:vldlrImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-971963. vldlr.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei794 – 815HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_500415836028 – 869Sequence analysisAdd BLAST842

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO42126.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini355 – 394EGF-likeInterPro annotationAdd BLAST40
Domaini395 – 430EGF-likeInterPro annotationAdd BLAST36

Keywords - Domaini

EGF-like domainSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG006250.
KOiK20053.

Family and domain databases

Gene3Di2.120.10.30. 1 hit.
4.10.400.10. 8 hits.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR023415. LDLR_class-A_CS.
IPR000033. LDLR_classB_rpt.
IPR002172. LDrepeatLR_classA_rpt.
IPR032931. VLDLR.
[Graphical view]
PANTHERiPTHR10529:SF101. PTHR10529:SF101. 1 hit.
PfamiPF07645. EGF_CA. 1 hit.
PF00057. Ldl_recept_a. 8 hits.
PF00058. Ldl_recept_b. 4 hits.
[Graphical view]
PRINTSiPR00261. LDLRECEPTOR.
SMARTiSM00181. EGF. 6 hits.
SM00179. EGF_CA. 2 hits.
SM00192. LDLa. 8 hits.
SM00135. LY. 5 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 2 hits.
SSF57424. SSF57424. 8 hits.
PROSITEiPS00010. ASX_HYDROXYL. 2 hits.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 2 hits.
PS01187. EGF_CA. 2 hits.
PS01209. LDLRA_1. 8 hits.
PS50068. LDLRA_2. 8 hits.
PS51120. LDLRB. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42126-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRSWRGVVL LLLLCFCLYP DLGLVHATTT LCEESQFQCG NGRCITSLWK
60 70 80 90 100
CDGDEDCSDG SDESSCVKKT CAESDFVCRN GQCVPSRWEC DGDPDCEDGS
110 120 130 140 150
DETPELCYMR TCRATEISCG VRSTQCIPLS WKCDGERDCA NAEDEENCGN
160 170 180 190 200
ITCSPSEFTC SSGRCISSTF VCNGQNDCSD GSDEVNCVPP TCGAHEFQCK
210 220 230 240 250
NFSCIPLSWV CDDEPDCADH SDESLEQCGR QPIAPQRCSA NEMPCGSGEC
260 270 280 290 300
IHKKWRCDGD ADCKDKSDEI NCPSRTCQPD QFKCEDGNCI HGSRQCDGVR
310 320 330 340 350
DCLDGTDEIR CKNVIQCSVP GKFKCKSGEC IESNKVCNKH KDCKDWSDEP
360 370 380 390 400
VKDCEVDECL ENNGGCSHIC HDLPIGYECE CTAGFKLIDR KTCGDIDECQ
410 420 430 440 450
NPEICSQICV NLKGGYKCEC SKGYQMDPST GVCKAVGREP CLIFTNRRDI
460 470 480 490 500
RKVGLERKEY IQLVEQLRNT VALDADIKEQ SLFWADTIQK AIFRAPFDTR
510 520 530 540 550
EKVGSHVKVV EDVHSPSAIA IDWIYKNIYW IDTILKTISV SNFDGSKRKT
560 570 580 590 600
LFSSELQDLT SIAVDPISGF IYWSDCGEPA KIEKAGMNGI DRQQLITADV
610 620 630 640 650
QRPSGIAIDV VKSRLYWVDS KLHTLSSVDL NGQDRRVILK SHEFLAHPLA
660 670 680 690 700
LTIFEDRVYW IDGENEAIYG ANKFSGQELE TLVNNLNDAQ DIIVYHELIQ
710 720 730 740 750
PLGINWCNEQ IENGGCKYLC LPAPQISDRS PKYTCACPDG FEVHEGRSCR
760 770 780 790 800
AGSKATMDHP VKPTGIMPNK PLPSGNNDTA SVYEVNQSAK GTSAAWAILP
810 820 830 840 850
LLLIAMAASG GYLMWRNWQR KNMKSMNFDN PVYLKTTEED LAIDIGRHSG
860
NIGHTYPAIS VVNTDDDLS
Length:869
Mass (Da):96,378
Last modified:January 1, 1998 - v1
Checksum:iA57A3B34072EB517
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006906 mRNA. Translation: BAA22145.1.
PIRiJC4858.
RefSeqiNP_001084168.1. NM_001090699.1.
UniGeneiXl.998.

Genome annotation databases

GeneIDi399346.
KEGGixla:399346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006906 mRNA. Translation: BAA22145.1.
PIRiJC4858.
RefSeqiNP_001084168.1. NM_001090699.1.
UniGeneiXl.998.

3D structure databases

ProteinModelPortaliO42126.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi399346.
KEGGixla:399346.

Organism-specific databases

CTDi7436.
XenbaseiXB-GENE-971963. vldlr.

Phylogenomic databases

HOVERGENiHBG006250.
KOiK20053.

Family and domain databases

Gene3Di2.120.10.30. 1 hit.
4.10.400.10. 8 hits.
InterProiIPR011042. 6-blade_b-propeller_TolB-like.
IPR001881. EGF-like_Ca-bd_dom.
IPR013032. EGF-like_CS.
IPR000742. EGF-like_dom.
IPR000152. EGF-type_Asp/Asn_hydroxyl_site.
IPR018097. EGF_Ca-bd_CS.
IPR009030. Growth_fac_rcpt_.
IPR023415. LDLR_class-A_CS.
IPR000033. LDLR_classB_rpt.
IPR002172. LDrepeatLR_classA_rpt.
IPR032931. VLDLR.
[Graphical view]
PANTHERiPTHR10529:SF101. PTHR10529:SF101. 1 hit.
PfamiPF07645. EGF_CA. 1 hit.
PF00057. Ldl_recept_a. 8 hits.
PF00058. Ldl_recept_b. 4 hits.
[Graphical view]
PRINTSiPR00261. LDLRECEPTOR.
SMARTiSM00181. EGF. 6 hits.
SM00179. EGF_CA. 2 hits.
SM00192. LDLa. 8 hits.
SM00135. LY. 5 hits.
[Graphical view]
SUPFAMiSSF57184. SSF57184. 2 hits.
SSF57424. SSF57424. 8 hits.
PROSITEiPS00010. ASX_HYDROXYL. 2 hits.
PS01186. EGF_2. 3 hits.
PS50026. EGF_3. 2 hits.
PS01187. EGF_CA. 2 hits.
PS01209. LDLRA_1. 8 hits.
PS50068. LDLRA_2. 8 hits.
PS51120. LDLRB. 5 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO42126_XENLA
AccessioniPrimary (citable) accession number: O42126
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: October 5, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.