Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Alpha1 integrin

Gene
N/A
Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IntegrinUniRule annotationSAAS annotationImported, ReceptorUniRule annotationSAAS annotation

Keywords - Biological processi

Cell adhesionUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha1 integrinImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

  • Membrane UniRule annotation; Single-pass type I membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1132 – 1156HelicalUniRule annotationAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17UniRule annotationAdd BLAST17
ChainiPRO_500142566818 – 1171UniRule annotationAdd BLAST1154

Proteomic databases

PaxDbiO42094.
PRIDEiO42094.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000032219.

Structurei

3D structure databases

ProteinModelPortaliO42094.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini162 – 345VWFAInterPro annotationAdd BLAST184

Sequence similaritiesi

Belongs to the integrin alpha chain family.UniRule annotationSAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3637. Eukaryota.
ENOG410XPVZ. LUCA.
HOVERGENiHBG006185.
KOiK06480.
PhylomeDBiO42094.

Family and domain databases

InterProiIPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
IPR032695. Integrin_dom.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01839. FG-GAP. 2 hits.
PF08441. Integrin_alpha2. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
PRINTSiPR01185. INTEGRINA.
SMARTiSM00191. Int_alpha. 4 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 3 hits.
PROSITEiPS51470. FG_GAP. 7 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
PS50234. VWFA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O42094-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASYWMLTA LFHLIGASNV DVKNAMTFSG PLEDMFGYTV QQYENEEGKW
60 70 80 90 100
VLIGSPLVGQ PEKRTGDVYK CPVGRDSQSP CIKLNLPDAT SVPNVMEVKE
110 120 130 140 150
NMTLGTTLVT NPKGGFLACG PLYAYKCGRL HYTTGVCSNV SSTFETVKAV
160 170 180 190 200
APSVQECKTQ LDIVIVLDGS NSIYPWESVT AFLNSLLRNM DIGPQQTQVG
210 220 230 240 250
IVQYGQTVVH EFYLNTYSTT EEVMDAALRI RQRGGTQTMT ALGIDTAREE
260 270 280 290 300
AFTEAHGARR GVQKVMVIVT DGESHDNYRL QEVIDKCEDE NIQRFAIAIL
310 320 330 340 350
GSYSRGNLST EKFVEEIKSI ASKPTEKHFF NVSDELALVT IVEALGERIF
360 370 380 390 400
ALEATTDQQA ASFEMEMSQA GFSAHYSQDW VMLGAVGAYD WNGTVVMVKD
410 420 430 440 450
SDISIPSNDT FRDRHSEKIE PLAAYLGYTV NSALTPGGVL YIAGQPRYNH
460 470 480 490 500
TGQVIIYKME GREVKVLQRL KGEQIGSYFG GVITTIDINR DSFTDLLLVG
510 520 530 540 550
APTYMGTEKE EQGKVYVYAL NKTKFEYQMS LEPIKQTCCS PLKHDTCKVL
560 570 580 590 600
KNEPCGARFG TAIAAVKDLN LDGYNDIVIG SPLEDDHRGA VYIYHGHGNT
610 620 630 640 650
ISKKYTQRIA SGGDGEKVKF FGQSVHGEMD LNDDGLIDVT IGGLGGAALF
660 670 680 690 700
WSRDVAEVNV SMQFMPKSIN IQQQNCQINK RKTICINATI CFKTRLKSKE
710 720 730 740 750
DIFESSLQYW ITLDAQRQIS RSLFTETHER KMQKNITIKG SECIKHNFYM
760 770 780 790 800
LDKPDFQDSV KVLLEFNFSD PESGPVLDSN LPNSISEYIP FTKDCGAKNK
810 820 830 840 850
CISDLALNVK ASIAGDSSSP FIVKSRNDRF TIQLSIKNKK DSAYNTRALV
860 870 880 890 900
QYSPNIIFAG IEDIQKDSCE SNHNITCKVG YPFLKPEEEI SFKISFQFNA
910 920 930 940 950
SYLLENATVD VYATSDSEEP PETLRDNRGQ VTIPVKYEVG LIFVSVFKEH
960 970 980 990 1000
HVIIAANETI PTAINTTEQI GDEVTLHYRI EKGEHFPMPN LTLQILYPDV
1010 1020 1030 1040 1050
TTAKNTLLYI TTLSHSQNAI CKSSYPVDHL KIGSGKSYVL PKIKEPTKDT
1060 1070 1080 1090 1100
IMECDTFSCA SINCALAPSD ISQVNVSLRV WKPTIIKASI HSLTLVVKAL
1110 1120 1130 1140 1150
LRSENSSLIL RNDHQKLETM IKISKEPPPG SVPLWVIPLS IFAGLLILAL
1160 1170
LIFALWKAGF FKRPLKKKME K
Length:1,171
Mass (Da):130,229
Last modified:January 1, 1998 - v1
Checksum:iB505A4D65F09736E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000470 mRNA. Translation: BAA23160.1.
PIRiA55348.
RefSeqiNP_990400.1. NM_205069.1.
UniGeneiGga.566.

Genome annotation databases

GeneIDi395951.
KEGGigga:395951.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000470 mRNA. Translation: BAA23160.1.
PIRiA55348.
RefSeqiNP_990400.1. NM_205069.1.
UniGeneiGga.566.

3D structure databases

ProteinModelPortaliO42094.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000032219.

Proteomic databases

PaxDbiO42094.
PRIDEiO42094.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395951.
KEGGigga:395951.

Organism-specific databases

CTDi3672.

Phylogenomic databases

eggNOGiKOG3637. Eukaryota.
ENOG410XPVZ. LUCA.
HOVERGENiHBG006185.
KOiK06480.
PhylomeDBiO42094.

Family and domain databases

InterProiIPR013517. FG-GAP.
IPR013519. Int_alpha_beta-p.
IPR000413. Integrin_alpha.
IPR013649. Integrin_alpha-2.
IPR018184. Integrin_alpha_C_CS.
IPR032695. Integrin_dom.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01839. FG-GAP. 2 hits.
PF08441. Integrin_alpha2. 1 hit.
PF00092. VWA. 1 hit.
[Graphical view]
PRINTSiPR01185. INTEGRINA.
SMARTiSM00191. Int_alpha. 4 hits.
SM00327. VWA. 1 hit.
[Graphical view]
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF69179. SSF69179. 3 hits.
PROSITEiPS51470. FG_GAP. 7 hits.
PS00242. INTEGRIN_ALPHA. 1 hit.
PS50234. VWFA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO42094_CHICK
AccessioniPrimary (citable) accession number: O42094
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.