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Protein

Ribonucleoside-diphosphate reductase

Gene

A629R

Organism
Paramecium bursaria Chlorella virus 1 (PBCV-1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.UniRule annotation

Catalytic activityi

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.UniRule annotation

Pathwayi: DNA replication

This protein is involved in the pathway DNA replication, which is part of Genetic information processing.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway DNA replication and in Genetic information processing.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

DNA replicationUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00326.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonucleoside-diphosphate reductaseUniRule annotation (EC:1.17.4.1UniRule annotation)
Gene namesi
Name:A629RImported
OrganismiParamecium bursaria Chlorella virus 1 (PBCV-1)Imported
Taxonomic identifieri10506 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePhycodnaviridaeChlorovirus
Virus hostiChlorella [TaxID: 114049]
Proteomesi
  • UP000000862 Componenti: Genome

Structurei

3D structure databases

ProteinModelPortaliO41111.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 117104ATP-coneInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ribonucleoside diphosphate reductase large chain family.UniRule annotation

Phylogenomic databases

KOiK10807.

Family and domain databases

InterProiIPR005144. ATP-cone_dom.
IPR013346. NrdE_NrdA.
IPR000788. RNR_lg_C.
IPR013509. RNR_lsu_N.
IPR008926. RNR_R1-su_N.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
PF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSiPR01183. RIBORDTASEM1.
SUPFAMiSSF48168. SSF48168. 1 hit.
TIGRFAMsiTIGR02506. NrdE_NrdA. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
PS00089. RIBORED_LARGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O41111-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGKTMNRTM NRTMVVLKRD GSKENISFDK ILQRIQRLCW PVNSKPVYKG
60 70 80 90 100
SRAMTGLNVD VSKIVASVCA SIVDGISTVQ LDELTADKSA SMTTEHPDYG
110 120 130 140 150
ILAARISVSN LQKQTHDKIT DAYAEIAHLL NEDFKENLEK HADEYQAFVD
160 170 180 190 200
YDRDYDFDYF GFKTMERLYL TKVGDKIVER PQHVYLRVAI GLWGSDIAKV
210 220 230 240 250
KETYDALSCR KFTHASPTLF NSGFKKAQLA SCFLMTVEDS LADIYKALGD
260 270 280 290 300
CAQLSKHGGG LGINISDIRG RGAMINGTNG ESDGIVPMLK VFDTTSAYAN
310 320 330 340 350
QGGRRKGSFA IYLEPHHPDI MDFLLMKRNQ GEESLRARNL FYAVWLNDLF
360 370 380 390 400
MKRVETDAQW SLFDPSECPG LTDAFGDEYA ELYTRYEAEG KAKNVVKARD
410 420 430 440 450
VWNTMVTTII ETGQPYVANK DTVNKKNMQS NAGTIRGSNL CIEILEYTSK
460 470 480 490 500
EETAVCVIGS VVLKNYVKND KFDFDDLRKN VKILAKNLDR SIDVMSYPIK
510 520 530 540 550
EAETSNKRRR PIGVGVQGLQ DVFFKLKLPF DSPEARDLNR EIFEHIYYAA
560 570 580 590 600
VEASVELAEI HGPHPTFEGS PASKGILQYH MWDVTPKSNL DWRGLEERVK
610 620 630 640 650
KGVRNSLLTA LMPTASTAQI CGSVEAFEPI TSNLYSRRTL AGEFPVVNSY
660 670 680 690 700
LVRELIERGT WSENMKNQII ANGGSIQKVI GIHPSVKAVY KTAWDLSMKS
710 720 730 740 750
VIDMAADRGA FVDQTQSMNL FLAQPTLKNV TSMLFYGWKS GLKSLQYYLR
760 770
SKPASSAIAV TVDTECVACS A
Length:771
Mass (Da):86,292
Last modified:January 1, 1998 - v1
Checksum:i8A2D97422E45069D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JF411744 Genomic DNA. Translation: AAC96959.1.
PIRiT18131.
RefSeqiNP_048985.1. NC_000852.5.

Genome annotation databases

GeneIDi917948.
KEGGivg:917948.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JF411744 Genomic DNA. Translation: AAC96959.1.
PIRiT18131.
RefSeqiNP_048985.1. NC_000852.5.

3D structure databases

ProteinModelPortaliO41111.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi917948.
KEGGivg:917948.

Phylogenomic databases

KOiK10807.

Enzyme and pathway databases

UniPathwayiUPA00326.

Family and domain databases

InterProiIPR005144. ATP-cone_dom.
IPR013346. NrdE_NrdA.
IPR000788. RNR_lg_C.
IPR013509. RNR_lsu_N.
IPR008926. RNR_R1-su_N.
[Graphical view]
PfamiPF03477. ATP-cone. 1 hit.
PF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSiPR01183. RIBORDTASEM1.
SUPFAMiSSF48168. SSF48168. 1 hit.
TIGRFAMsiTIGR02506. NrdE_NrdA. 1 hit.
PROSITEiPS51161. ATP_CONE. 1 hit.
PS00089. RIBORED_LARGE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO41111_PBCV1
AccessioniPrimary (citable) accession number: O41111
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: July 6, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.