A544R

Functionⁱ

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	32	AMPCombined sources	1
Binding siteⁱ	67	AMPCombined sources	1
Binding siteⁱ	98	AMPCombined sources	1

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	25 – 28	AMPCombined sources		4
Nucleotide bindingⁱ	186 – 188	AMPCombined sources		3

GO - Molecular functionⁱ

ATP binding Source: InterPro
DNA ligase (ATP) activity Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

DNA ligation involved in DNA repair Source: InterPro
DNA recombination Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	LigaseImported
Ligand	Nucleotide-bindingCombined sources

Enzyme and pathway databases

BRENDAⁱ	6.5.1.1. 8088.

BRENDAⁱ

6.5.1.1. 8088.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: ATP-dependent DNA ligaseImported
Gene namesⁱ	Name:A544RImported
Organismⁱ	Paramecium bursaria Chlorella virus 1 (PBCV-1)Imported
Taxonomic identifierⁱ	10506 [NCBI]
Taxonomic lineageⁱ	Viruses › dsDNA viruses, no RNA stage › Phycodnaviridae › Chlorovirus
Virus hostⁱ	Chlorella [TaxID: 114049]
Proteomesⁱ	UP000000862 Componentⁱ: Genome

Structureⁱ

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1P8L	X-ray	2.95	A	1-298	[»]
	2Q2T	X-ray	2.30	A	1-298	[»]
	2Q2U	X-ray	3.00	A/B/C/D	1-298	[»]
ProteinModelPortalⁱ	O41026.
SMRⁱ	O41026.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	O41026.

EvolutionaryTraceⁱ

O41026.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	7 – 177	DNA_LIGASE_A3InterPro annotationAdd BLAST		171
Domainⁱ	230 – 293	DNA_ligase_OB_2InterPro annotationAdd BLAST		64

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K10747.
Database of Orthologous Groups More...OrthoDBⁱ	VOG090001TM.

Family and domain databases

InterProⁱ	View protein in InterPro IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR029319. DNA_ligase_OB. IPR012340. NA-bd_OB-fold.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01068. DNA_ligase_A_M. 1 hit. PF14743. DNA_ligase_OB_2. 1 hit.
SUPFAMⁱ	SSF50249. SSF50249. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00333. DNA_LIGASE_A2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

O41026-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAITKPLLAA TLENIEDVQF PCLATPKIDG IRSVKQTQML SRTFKPIRNS 
        60         70         80         90        100
VMNRLLTELL PEGSDGEISI EGATFQDTTS AVMTGHKMYN AKFSYYWFDY 
       110        120        130        140        150
VTDDPLKKYI DRVEDMKNYI TVHPHILEHA QVKIIPLIPV EINNITELLQ 
       160        170        180        190        200
YERDVLSKGF EGVMIRKPDG KYKFGRSTLK EGILLKMKQF KDAEATIISM 
       210        220        230        240        250
TALFKNTNTK TKDNFGYSKR STHKSGKVEE DVMGSIEVDY DGVVFSIGTG 
       260        270        280        290 
FDADQRRDFW QNKESYIGKM VKFKYFEMGS KDCPRFPVFI GIRHEEDR

Length:298

Mass (Da):34,250

Last modified:January 1, 1998 - v1

Checksum:ⁱ01E5A8094FF558F8

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	JF411744 Genomic DNA. Translation: AAC96909.1.
PIRⁱ	T18046.
NCBI Reference Sequences More...RefSeqⁱ	NP_048900.1. NC_000852.5.

Genome annotation databases

GeneIDⁱ	917798.
KEGGⁱ	vg:917798.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	JF411744 Genomic DNA. Translation: AAC96909.1.
PIRⁱ	T18046.
NCBI Reference Sequences More...RefSeqⁱ	NP_048900.1. NC_000852.5.

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1P8L	X-ray	2.95	A	1-298	[»]
	2Q2T	X-ray	2.30	A	1-298	[»]
	2Q2U	X-ray	3.00	A/B/C/D	1-298	[»]
ProteinModelPortalⁱ	O41026.
SMRⁱ	O41026.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	917798.
KEGGⁱ	vg:917798.

Phylogenomic databases

KEGG Orthology (KO) More...KOⁱ	K10747.
Database of Orthologous Groups More...OrthoDBⁱ	VOG090001TM.

Enzyme and pathway databases

BRENDAⁱ	6.5.1.1. 8088.

BRENDAⁱ

6.5.1.1. 8088.

Miscellaneous databases

EvolutionaryTraceⁱ	O41026.

EvolutionaryTraceⁱ

O41026.

Family and domain databases

InterProⁱ	View protein in InterPro IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR029319. DNA_ligase_OB. IPR012340. NA-bd_OB-fold.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01068. DNA_ligase_A_M. 1 hit. PF14743. DNA_ligase_OB_2. 1 hit.
SUPFAMⁱ	SSF50249. SSF50249. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00333. DNA_LIGASE_A2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	O41026_PBCV1
Accessionⁱ	O41026Primary (citable) accession number: O41026
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	January 1, 1998
	Last sequence update:	January 1, 1998
	Last modified:	July 5, 2017
	This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources, Complete proteome, Reference proteomeImported

UniProtKB - O41026 (O41026_PBCV1)

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ATP-dependent DNA ligase

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Functionⁱ

Sites

Regions

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Structureⁱ

3D structure databases

Miscellaneous databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O41026 (O41026_PBCV1)

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ATP-dependent DNA ligase

A544R

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ