ID   O40925_HHV8             Unreviewed;      1376 AA.
AC   O40925;
DT   01-JAN-1998, integrated into UniProtKB/TrEMBL.
DT   01-JAN-1998, sequence version 1.
DT   27-MAR-2024, entry version 62.
DE   SubName: Full=ORf 25 {ECO:0000313|EMBL:AAB62606.1};
OS   Human herpesvirus 8 (HHV-8) (Kaposi's sarcoma-associated herpesvirus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Orthoherpesviridae; Gammaherpesvirinae; Rhadinovirus;
OC   Rhadinovirus humangamma8.
OX   NCBI_TaxID=37296 {ECO:0000313|EMBL:AAB62606.1};
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1] {ECO:0000313|EMBL:AAB62606.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=9151804;
RA   Neipel F., Albrecht J.C., Fleckenstein B.;
RT   "Cell-homologous genes in the Kaposi's sarcoma-associated rhadinovirus
RT   human herpesvirus 8: determinants of its pathogenicity?";
RL   J. Virol. 71:4187-4192(1997).
RN   [2] {ECO:0000313|EMBL:AAB62606.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Neipel F., Albrecht J.-C., Ensser A., Huang Y.-Q., Li J.J.,
RA   Friedman-Kien A.E., Fleckenstein B.;
RT   "The genome of human herpesvirus 8 cloned from Kaposi's sarcoma.";
RL   Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- INTERACTION:
CC       O40925; O40942; NbExp=2; IntAct=EBI-2608602, EBI-2608626;
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DR   EMBL; U93872; AAB62606.1; -; Genomic_DNA.
DR   IntAct; O40925; 2.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039622; C:T=16 icosahedral viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04016; HSV_MCP; 1.
DR   InterPro; IPR000912; Herpes_MCP.
DR   InterPro; IPR023233; Herpes_MCP_upper_sf.
DR   Pfam; PF03122; Herpes_MCP; 1.
DR   PRINTS; PR00235; HSVCAPSIDMCP.
DR   SUPFAM; SSF103417; Major capsid protein VP5; 1.
PE   1: Evidence at protein level;
KW   Capsid protein {ECO:0000256|ARBA:ARBA00022680};
KW   T=16 icosahedral capsid protein {ECO:0000256|ARBA:ARBA00022680};
KW   Virion {ECO:0000256|ARBA:ARBA00022680}.
SQ   SEQUENCE   1376 AA;  153464 MW;  F10B59E380745A49 CRC64;
     MEATLEQRPF PYLATEANLL TQIKESAADG LFKSFQLLLG KDAREGSVRF EALLGVYTNV
     VEFVKFLETA LAAACVNTEF KDLRRMIDGK IQFKISMPTI AHGDGRRPNK QRQYIVMKAC
     NKHHIGAEIE LAAADIELLF AEKETPLDFT EYAGAIKTIT SALQFGMDAL ERGLVDTVLA
     VKLRHAPPVF ILKTLGDPVY SERGLKKAVK SDMVSMFKAH LIEHSFFLDK AELMTRGKQY
     VLTMLSDMLA AVCEDTVFKG VSTYTTASGQ QVAGVLETTD SVMRRLMNLL GQVESAMSGP
     AAYASYVVRG ANLVTAVSYG RAMRNFEQFM ARIVDHPNAL PSVEGDKAAL ADGHDEIQRT
     RIAASLVKIG DKFVAIESLQ RMYNETQFPC PLNRRIQYTY FFPVGLHLPV PRYSTSVSVR
     GVESPAIQST ETWVVNKNNV PLCFGYQNAL KSICHPRMHN PTQSAQALNQ AFPDPDGGHG
     YGLRYEQTPN MNLFRTFHQY YMGKNVAFVP DVAQKALVTT EDLLHPTSHR LLRLEVHPFF
     DFFVHPCPGA RGSYRATHRT MVGNIPQPLA PREFQESRGA QFDDVTNMTH VIDQLTIDVI
     QETAFDPAYP LFCYVIEAMI HGQEEKFVMN MPLIALVIQT YWVNSGKLAF VNSYHMVRFI
     CTHMGNGSIP KEAHGHYRKI LGELIALEQA LLKLAGHETV GRTPITHLVS ALLDPHLLPP
     FAYHDVFTDL MQKSSRQPII KIGDQNYDNP QNRATFINLR GRMEDLVNNL VNIYQTRVNE
     DHDERHVLDV APLDENDYNP VLEKLFYYVL MPVCSNGHMC GMGVDYQNVA LTLTYNGPVF
     ADVVNAQDDI LLHLENGTLK DILQAGDIRP TVDMIRVLCT SFLTCPFVTQ AARVITKRDP
     AQSFATHEYG KDVAQTVLVN GFGAFAVADR SREAAETMFY PVPFNKLYAD PLVAATLHPL
     LANYVTRLPN QRNAVVFNVP SNLMAEYEEW HKSPVAAYAA SCQATPGAIS AMVSMHQKLS
     APSFICQAKH RMHPGFAMTV VRTDEVLAEH ILYCSRASTS MFVGLPSVVR REVRSDAVTF
     EITHEIASLH TALGYSSVIA PAHVAAITTD MGVHCQDLFM IFPGDAYQDR QLHDYIKMKA
     GVQTGSPGNR MDHVGYTAGV PRCENLPGLS HGQLATCEII PTPVTSDVAY FQTPSNPRGR
     AACVVSCDAY SNESAERLLY DHSIPDPAYE CRSTNNPWAS QRGSLGDVLY NITFRQTALP
     GMYSPCRQFF HKEDIMRYNR GLYTLVNEYS ARLAGAPATS TTDLQYVVVN GTDVFLDQPC
     HMLQEAYPTL AASHRVMLDE YMSNKQTHAP VHMGQYLIEE VAPMKRLLKL GNKVVY
//