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O36203

- O36203_9HIV1

UniProt

O36203 - O36203_9HIV1

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Protein
Submitted name:

Vpr protein

Gene

vpr

Organism
Human immunodeficiency virus 1
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
  4. viral entry into host cell Source: UniProtKB-KW
  5. viral penetration into host nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

ActivatorSAAS annotation

Keywords - Biological processi

Cell cycleSAAS annotation, Host-virus interactionSAAS annotation, Transcription, Transcription regulationSAAS annotation, Viral penetration into host nucleusSAAS annotation, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Submitted name:
Vpr proteinImported
Gene namesi
Name:vprImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

GO - Cellular componenti

  1. host cell nucleus Source: UniProtKB-KW
  2. virion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Host nucleusSAAS annotation, VirionSAAS annotation

Pathology & Biotechi

Keywords - Diseasei

AIDSUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO36203.
SMRiO36203. Positions 1-96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR000012. RetroV_VpR/X.
[Graphical view]
PfamiPF00522. VPR. 1 hit.
[Graphical view]
PRINTSiPR00444. HIVVPRVPX.

Sequencei

Sequence statusi: Complete.

O36203-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEQAPEDQGP QREPYNEWTL ELLEELKNEA VRHFPRPWLH SLGQHIYETY
60 70 80 90
GDTWAGVEAI IRILQQLLFI HFRIGCQHSR IGITRQRRAR NGASRS
Length:96
Mass (Da):11,349
Last modified:January 1, 1998 - v1
Checksum:i06954E5151109B4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000315 Genomic DNA. Translation: AAB70154.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF000315 Genomic DNA. Translation: AAB70154.1 .

3D structure databases

ProteinModelPortali O36203.
SMRi O36203. Positions 1-96.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR000012. RetroV_VpR/X.
[Graphical view ]
Pfami PF00522. VPR. 1 hit.
[Graphical view ]
PRINTSi PR00444. HIVVPRVPX.
ProtoNeti Search...

Publicationsi

  1. "A unique and discontinuous distribution of phylogenetically distinct HIV-1 variants in a single time point it plasma and peripheral blood mononuclear cells of patients with terminal AIDS."
    Song J., Wang B., Ge Y.C., Dwyer D., Dowton D., Cunningham A., Saksena N.
    Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO36203_9HIV1
AccessioniPrimary (citable) accession number: O36203
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: January 7, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.