O36022 (MNN9_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Mannan polymerase complex subunit mnn9

Gene names

Name:	mnn9
ORF Names:	SPAC4F10.10c

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	337 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Required for the addition of the long alpha 1,6-mannose backbone of N-linked glycans on cell wall and periplasmic proteins By similarity.
Pathway	Protein modification; protein glycosylation. UniProtKB P39107
Subcellular location	Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note: Cis-Golgi. Recycles between endoplasmic reticulum and Golgi. Ref.2 UniProtKB P39107
Sequence similarities	Belongs to the ANP1/MMN9/VAN1 family.

Ontologies

Keywords
Cellular component	Endoplasmic reticulum Golgi apparatus Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	negative regulation of G0 to G1 transition Inferred from mutant phenotype. Source: GeneDB_Spombe protein N-linked glycosylation Inferred from sequence or structural similarity. Source: GeneDB_Spombe
Cellular component	Golgi membrane Inferred from electronic annotation. Source: UniProtKB-SubCell alpha-1,6-mannosyltransferase complex Inferred from sequence or structural similarity. Source: GeneDB_Spombe endoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 337	337	Mannan polymerase complex subunit mnn9		PRO_0000316855
Regions
	Topological domain	1 – 8	8	Cytoplasmic Potential UniProtKB P39107
	Transmembrane	9 – 29	21	Helical; Signal-anchor for type II membrane protein; Potential UniProtKB P39107
	Topological domain	30 – 337	308	Lumenal Potential UniProtKB P39107

Sequences

	Sequence		Length	Mass (Da)
	O36022 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 4309DAA98590478A	FASTA	337	38,297
	10 20 30 40 50 60 MRVYNKSRIV GQLLFVALGI TFIYYLFTPS VNSNAKVQIE NRGGNSYEIY DMNKITESSD 70 80 90 100 110 120 PIRNKEEVLI LTPIARFYPQ YWKNLLELDY PRNLISLGFI VPSSKDGAKV HRELRNAINA 130 140 150 160 170 180 VQKGPGDKRF ADVKILIQDS DLSSGQSEAE RHKFSAQKER RGKLAATRNT LLLSTLKPST 190 200 210 220 230 240 SWVLWLDSDI VETPSTLIQD LAEHNEDVLV ANCFQKQGDK LTPYDFNSWV DSQTAQELAS 250 260 270 280 290 300 HMDRDEILLE GYAELPTYRM LMAKIYEEHK DPSTIMALDG VGTTALLVKA SVHRDGALFP 310 320 330 TFPFYHLIES EGFAKMAKRL GHGVYGLPYY LVFHHNE

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed: 16823372] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329670 Genomic DNA. Translation: CAB11713.1.
PIR	T38814.
RefSeq	NP_594753.1. NM_001020180.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	O36022.
Protein family/group databases
CAZy	GT62. Glycosyltransferase Family 62.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPAC4F10.10c.1; SPAC4F10.10c.1:pep; SPAC4F10.10c.
GeneID	2543252.
GenomeReviews	Gene locus mnn9 in contig CU329670_GR.
KEGG	spo:SPAC4F10.10c.
NMPDR	fig|4896.1.peg.4723.
Organism-specific databases
GeneDB_Spombe	SPAC4F10.10c.
Phylogenomic databases
eggNOG	fuNOG05503.
GeneTree	EFGT00050000002721.
HOGENOM	HBG396793.
OMA	GLPNYLV.
OrthoDB	EOG4J9R7K.
Gene expression databases
ArrayExpress	O36022.
Family and domain databases
InterPro	IPR005109. Anp1. [Graphical view]
KO	K05529.
Pfam	PF03452. Anp1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MNN9_SCHPO

Accession

Primary (citable) accession number: O36022

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 1, 1998
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program