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Protein

39S ribosomal protein L23, mitochondrial

Gene

Mrpl23

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L23, mitochondrial
Short name:
L23mt
Short name:
MRP-L23
Alternative name(s):
L23 mitochondrial-related protein
Gene namesi
Name:Mrpl23
Synonyms:L23mrp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1196612. Mrpl23.

Subcellular locationi

  • Mitochondrion By similarity

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: UniProtKB
  • mitochondrial ribosome Source: MGI
  • mitochondrion Source: MGI
  • nucleolus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001294851 – 14639S ribosomal protein L23, mitochondrialAdd BLAST146

Proteomic databases

EPDiO35972.
MaxQBiO35972.
PaxDbiO35972.
PeptideAtlasiO35972.
PRIDEiO35972.

PTM databases

iPTMnetiO35972.
PhosphoSitePlusiO35972.

Expressioni

Gene expression databases

BgeeiENSMUSG00000037772.
CleanExiMM_MRPL23.
GenevisibleiO35972. MM.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi202972. 1 interactor.
DIPiDIP-61654N.
STRINGi10090.ENSMUSP00000039784.

Structurei

3D structure databases

ProteinModelPortaliO35972.
SMRiO35972.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L23P family.Curated

Phylogenomic databases

eggNOGiKOG4089. Eukaryota.
ENOG4111IAB. LUCA.
GeneTreeiENSGT00390000007739.
HOGENOMiHOG000231896.
HOVERGENiHBG052914.
InParanoidiO35972.
KOiK02892.
OMAiEMTKYDV.
OrthoDBiEOG091G16EY.
PhylomeDBiO35972.
TreeFamiTF105852.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR013025. Ribosomal_L25/23.
[Graphical view]
PfamiPF00276. Ribosomal_L23. 1 hit.
[Graphical view]
SUPFAMiSSF54189. SSF54189. 1 hit.

Sequencei

Sequence statusi: Complete.

O35972-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARNVLYPLY QLGGPQLRVF RTNFFIQLVR PGTAQPEDTV QFRIPMEMTR
60 70 80 90 100
VDLRNYLEQI YNVPVAAVRT RVQHGSNRRR DHKNVRIKKP DYKVAYVQLA
110 120 130 140
HGQTFTFPDL FPEKDPRSPE PLEEELPQQR QSSDLRCPGI PSWFGL
Length:146
Mass (Da):17,122
Last modified:January 1, 1998 - v1
Checksum:i0116ADE56C9B1553
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U84902 mRNA. Translation: AAC53392.1.
U84903 Genomic DNA. Translation: AAC53393.1.
AB049646 mRNA. Translation: BAB40851.1.
AK086805 mRNA. Translation: BAC39746.1.
BC081460 mRNA. Translation: AAH81460.1.
U71209 Genomic DNA. Translation: AAB70459.1.
CCDSiCCDS22032.1.
RefSeqiNP_035418.1. NM_011288.1.
UniGeneiMm.12144.

Genome annotation databases

EnsembliENSMUST00000038675; ENSMUSP00000039784; ENSMUSG00000037772.
GeneIDi19935.
KEGGimmu:19935.
UCSCiuc009kny.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U84902 mRNA. Translation: AAC53392.1.
U84903 Genomic DNA. Translation: AAC53393.1.
AB049646 mRNA. Translation: BAB40851.1.
AK086805 mRNA. Translation: BAC39746.1.
BC081460 mRNA. Translation: AAH81460.1.
U71209 Genomic DNA. Translation: AAB70459.1.
CCDSiCCDS22032.1.
RefSeqiNP_035418.1. NM_011288.1.
UniGeneiMm.12144.

3D structure databases

ProteinModelPortaliO35972.
SMRiO35972.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi202972. 1 interactor.
DIPiDIP-61654N.
STRINGi10090.ENSMUSP00000039784.

PTM databases

iPTMnetiO35972.
PhosphoSitePlusiO35972.

Proteomic databases

EPDiO35972.
MaxQBiO35972.
PaxDbiO35972.
PeptideAtlasiO35972.
PRIDEiO35972.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000038675; ENSMUSP00000039784; ENSMUSG00000037772.
GeneIDi19935.
KEGGimmu:19935.
UCSCiuc009kny.1. mouse.

Organism-specific databases

CTDi6150.
MGIiMGI:1196612. Mrpl23.

Phylogenomic databases

eggNOGiKOG4089. Eukaryota.
ENOG4111IAB. LUCA.
GeneTreeiENSGT00390000007739.
HOGENOMiHOG000231896.
HOVERGENiHBG052914.
InParanoidiO35972.
KOiK02892.
OMAiEMTKYDV.
OrthoDBiEOG091G16EY.
PhylomeDBiO35972.
TreeFamiTF105852.

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Miscellaneous databases

PROiO35972.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000037772.
CleanExiMM_MRPL23.
GenevisibleiO35972. MM.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR013025. Ribosomal_L25/23.
[Graphical view]
PfamiPF00276. Ribosomal_L23. 1 hit.
[Graphical view]
SUPFAMiSSF54189. SSF54189. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRM23_MOUSE
AccessioniPrimary (citable) accession number: O35972
Secondary accession number(s): Q78E46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.