Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

O35972

- RM23_MOUSE

UniProt

O35972 - RM23_MOUSE

Protein

39S ribosomal protein L23, mitochondrial

Gene

Mrpl23

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. nucleotide binding Source: InterPro
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    39S ribosomal protein L23, mitochondrial
    Short name:
    L23mt
    Short name:
    MRP-L23
    Alternative name(s):
    L23 mitochondrial-related protein
    Gene namesi
    Name:Mrpl23
    Synonyms:L23mrp
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:1196612. Mrpl23.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: MGI
    2. ribosome Source: UniProtKB-KW

    Keywords - Cellular componenti

    Mitochondrion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 14614639S ribosomal protein L23, mitochondrialPRO_0000129485Add
    BLAST

    Proteomic databases

    MaxQBiO35972.
    PaxDbiO35972.
    PRIDEiO35972.

    PTM databases

    PhosphoSiteiO35972.

    Expressioni

    Gene expression databases

    BgeeiO35972.
    CleanExiMM_MRPL23.
    GenevestigatoriO35972.

    Interactioni

    Protein-protein interaction databases

    BioGridi202972. 7 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliO35972.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L23P family.Curated

    Phylogenomic databases

    eggNOGiNOG309821.
    GeneTreeiENSGT00390000007739.
    HOGENOMiHOG000231896.
    HOVERGENiHBG052914.
    InParanoidiO35972.
    KOiK02892.
    OMAiRVFLPNF.
    OrthoDBiEOG7BGHNC.
    PhylomeDBiO35972.
    TreeFamiTF105852.

    Family and domain databases

    Gene3Di3.30.70.330. 1 hit.
    InterProiIPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR013025. Ribosomal_L25/23.
    [Graphical view]
    PfamiPF00276. Ribosomal_L23. 1 hit.
    [Graphical view]
    SUPFAMiSSF54189. SSF54189. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    O35972-1 [UniParc]FASTAAdd to Basket

    « Hide

    MARNVLYPLY QLGGPQLRVF RTNFFIQLVR PGTAQPEDTV QFRIPMEMTR    50
    VDLRNYLEQI YNVPVAAVRT RVQHGSNRRR DHKNVRIKKP DYKVAYVQLA 100
    HGQTFTFPDL FPEKDPRSPE PLEEELPQQR QSSDLRCPGI PSWFGL 146
    Length:146
    Mass (Da):17,122
    Last modified:January 1, 1998 - v1
    Checksum:i0116ADE56C9B1553
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U84902 mRNA. Translation: AAC53392.1.
    U84903 Genomic DNA. Translation: AAC53393.1.
    AB049646 mRNA. Translation: BAB40851.1.
    AK086805 mRNA. Translation: BAC39746.1.
    BC081460 mRNA. Translation: AAH81460.1.
    U71209 Genomic DNA. Translation: AAB70459.1.
    CCDSiCCDS22032.1.
    RefSeqiNP_035418.1. NM_011288.1.
    UniGeneiMm.12144.

    Genome annotation databases

    EnsembliENSMUST00000038675; ENSMUSP00000039784; ENSMUSG00000037772.
    GeneIDi19935.
    KEGGimmu:19935.
    UCSCiuc009kny.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U84902 mRNA. Translation: AAC53392.1 .
    U84903 Genomic DNA. Translation: AAC53393.1 .
    AB049646 mRNA. Translation: BAB40851.1 .
    AK086805 mRNA. Translation: BAC39746.1 .
    BC081460 mRNA. Translation: AAH81460.1 .
    U71209 Genomic DNA. Translation: AAB70459.1 .
    CCDSi CCDS22032.1.
    RefSeqi NP_035418.1. NM_011288.1.
    UniGenei Mm.12144.

    3D structure databases

    ProteinModelPortali O35972.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 202972. 7 interactions.

    PTM databases

    PhosphoSitei O35972.

    Proteomic databases

    MaxQBi O35972.
    PaxDbi O35972.
    PRIDEi O35972.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000038675 ; ENSMUSP00000039784 ; ENSMUSG00000037772 .
    GeneIDi 19935.
    KEGGi mmu:19935.
    UCSCi uc009kny.1. mouse.

    Organism-specific databases

    CTDi 6150.
    MGIi MGI:1196612. Mrpl23.

    Phylogenomic databases

    eggNOGi NOG309821.
    GeneTreei ENSGT00390000007739.
    HOGENOMi HOG000231896.
    HOVERGENi HBG052914.
    InParanoidi O35972.
    KOi K02892.
    OMAi RVFLPNF.
    OrthoDBi EOG7BGHNC.
    PhylomeDBi O35972.
    TreeFami TF105852.

    Miscellaneous databases

    NextBioi 297449.
    PROi O35972.
    SOURCEi Search...

    Gene expression databases

    Bgeei O35972.
    CleanExi MM_MRPL23.
    Genevestigatori O35972.

    Family and domain databases

    Gene3Di 3.30.70.330. 1 hit.
    InterProi IPR012677. Nucleotide-bd_a/b_plait.
    IPR012678. Ribosomal_L23/L15e_core_dom.
    IPR013025. Ribosomal_L25/23.
    [Graphical view ]
    Pfami PF00276. Ribosomal_L23. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54189. SSF54189. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers."
      Zubair M., Hilton K., Saam J.R., Surani M.A., Tilghman S.M., Sasaki H.
      Genomics 45:290-296(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
      Strain: 129/SvJ.
      Tissue: Liver.
    2. "Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
      Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
      J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    3. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Lung.
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Brain.
    5. "Matrix-attachment regions in the mouse chromosome 7F imprinted domain."
      Greally J.M., Guinness M.E., McGrath J., Zemel S.
      Mamm. Genome 8:805-810(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-44.
      Strain: C57BL/6.

    Entry informationi

    Entry nameiRM23_MOUSE
    AccessioniPrimary (citable) accession number: O35972
    Secondary accession number(s): Q78E46
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 5, 2005
    Last sequence update: January 1, 1998
    Last modified: October 1, 2014
    This is version 113 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3