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O35972 (RM23_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 109. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
39S ribosomal protein L23, mitochondrial

Short name=L23mt
Short name=MRP-L23
Alternative name(s):
L23 mitochondrial-related protein
Gene names
Name:Mrpl23
Synonyms:L23mrp
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length146 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Mitochondrion.

Sequence similarities

Belongs to the ribosomal protein L23P family.

Ontologies

Keywords
   Cellular componentMitochondrion
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmitochondrion

Inferred from direct assay PubMed 18614015. Source: MGI

ribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionnucleotide binding

Inferred from electronic annotation. Source: InterPro

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14614639S ribosomal protein L23, mitochondrial
PRO_0000129485

Sequences

Sequence LengthMass (Da)Tools
O35972 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 0116ADE56C9B1553

FASTA14617,122
        10         20         30         40         50         60 
MARNVLYPLY QLGGPQLRVF RTNFFIQLVR PGTAQPEDTV QFRIPMEMTR VDLRNYLEQI 

        70         80         90        100        110        120 
YNVPVAAVRT RVQHGSNRRR DHKNVRIKKP DYKVAYVQLA HGQTFTFPDL FPEKDPRSPE 

       130        140 
PLEEELPQQR QSSDLRCPGI PSWFGL 

« Hide

References

« Hide 'large scale' references
[1]"Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers."
Zubair M., Hilton K., Saam J.R., Surani M.A., Tilghman S.M., Sasaki H.
Genomics 45:290-296(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
Strain: 129/SvJ.
Tissue: Liver.
[2]"Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Lung.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6.
Tissue: Brain.
[5]"Matrix-attachment regions in the mouse chromosome 7F imprinted domain."
Greally J.M., Guinness M.E., McGrath J., Zemel S.
Mamm. Genome 8:805-810(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-44.
Strain: C57BL/6.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U84902 mRNA. Translation: AAC53392.1.
U84903 Genomic DNA. Translation: AAC53393.1.
AB049646 mRNA. Translation: BAB40851.1.
AK086805 mRNA. Translation: BAC39746.1.
BC081460 mRNA. Translation: AAH81460.1.
U71209 Genomic DNA. Translation: AAB70459.1.
RefSeqNP_035418.1. NM_011288.1.
UniGeneMm.12144.

3D structure databases

ProteinModelPortalO35972.
SMRO35972. Positions 36-107.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid202972. 7 interactions.

PTM databases

PhosphoSiteO35972.

Proteomic databases

PaxDbO35972.
PRIDEO35972.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000038675; ENSMUSP00000039784; ENSMUSG00000037772.
GeneID19935.
KEGGmmu:19935.
UCSCuc009kny.1. mouse.

Organism-specific databases

CTD6150.
MGIMGI:1196612. Mrpl23.

Phylogenomic databases

eggNOGNOG309821.
GeneTreeENSGT00390000007739.
HOGENOMHOG000231896.
HOVERGENHBG052914.
InParanoidO35972.
KOK02892.
OMARVFLPNF.
OrthoDBEOG7BGHNC.
PhylomeDBO35972.
TreeFamTF105852.

Gene expression databases

BgeeO35972.
CleanExMM_MRPL23.
GenevestigatorO35972.

Family and domain databases

Gene3D3.30.70.330. 1 hit.
InterProIPR012677. Nucleotide-bd_a/b_plait.
IPR012678. Ribosomal_L23/L15e_core_dom.
IPR013025. Ribosomal_L25/23.
[Graphical view]
PfamPF00276. Ribosomal_L23. 1 hit.
[Graphical view]
SUPFAMSSF54189. SSF54189. 1 hit.
ProtoNetSearch...

Other

NextBio297449.
PROO35972.
SOURCESearch...

Entry information

Entry nameRM23_MOUSE
AccessionPrimary (citable) accession number: O35972
Secondary accession number(s): Q78E46
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot