Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Na/taurocholate cotransporting polypeptide 2

Gene

Slc10a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BRENDAi2.7.1.137. 3474.

Names & Taxonomyi

Protein namesi
Submitted name:
Na/taurocholate cotransporting polypeptide 2Imported
Submitted name:
Solute carrier family 10 (Sodium/bile acid cotransporter family), member 1, isoform CRA_dImported
Gene namesi
Name:Slc10a1Imported
Synonyms:NtcpImported
ORF Names:mCG_7625Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97379. Slc10a1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4823HelicalSequence analysisAdd
BLAST
Transmembranei60 – 7920HelicalSequence analysisAdd
BLAST
Transmembranei118 – 14225HelicalSequence analysisAdd
BLAST
Transmembranei154 – 17623HelicalSequence analysisAdd
BLAST
Transmembranei188 – 20821HelicalSequence analysisAdd
BLAST
Transmembranei228 – 24619HelicalSequence analysisAdd
BLAST
Transmembranei287 – 30822HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093229.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2718. Eukaryota.
COG0385. LUCA.
HOVERGENiHBG101123.

Family and domain databases

InterProiIPR002657. BilAc:Na_symport/Acr3.
IPR004710. Bilac:Na_transpt.
IPR030208. SLC10A1.
[Graphical view]
PANTHERiPTHR10361. PTHR10361. 1 hit.
PTHR10361:SF40. PTHR10361:SF40. 1 hit.
PfamiPF01758. SBF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00841. bass. 1 hit.

Sequencei

Sequence statusi: Complete.

O35940-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAHNVSAPF NFSLPPGFGH RATDTALSVI LVVMLLLIML SLGCTMEFSK
60 70 80 90 100
IKAHFWKPKG VIIAIVAQYG IMPLSAFLLG KVFHLTSIEA LAILICGCSP
110 120 130 140 150
GGNLSNLFTL AMKGDMNLSI VMTTCSSFTA LGMMPLLLYI YSKGIYDGDL
160 170 180 190 200
KDKVPYKGIM LSLVMVLIPC AIGIFLKSKR PHYVPYVLKA GMIITFSLSV
210 220 230 240 250
AVTVLSVINV GNSIMFVMTP HLLATSSLMP FTGFLMGYIL SALFRLNPSC
260 270 280 290 300
RRTISMETGF QNVQLCSTIL NVTFPPEVIG PLFFFPLLYM IFQLAEGLLF
310
IIIFRCYLKI KPQKGKY
Length:317
Mass (Da):34,886
Last modified:January 1, 1998 - v1
Checksum:iDA32C829C8A8E6D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U95132 mRNA. Translation: AAB81024.1.
CH466590 Genomic DNA. Translation: EDL02698.1.
RefSeqiNP_035517.1. NM_011387.2.
UniGeneiMm.486361.

Genome annotation databases

GeneIDi20493.
UCSCiuc007obs.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U95132 mRNA. Translation: AAB81024.1.
CH466590 Genomic DNA. Translation: EDL02698.1.
RefSeqiNP_035517.1. NM_011387.2.
UniGeneiMm.486361.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000093229.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi20493.
UCSCiuc007obs.2. mouse.

Organism-specific databases

CTDi6554.
MGIiMGI:97379. Slc10a1.

Phylogenomic databases

eggNOGiKOG2718. Eukaryota.
COG0385. LUCA.
HOVERGENiHBG101123.

Enzyme and pathway databases

BRENDAi2.7.1.137. 3474.

Miscellaneous databases

ChiTaRSiSlc10a1. mouse.
SOURCEiSearch...

Family and domain databases

InterProiIPR002657. BilAc:Na_symport/Acr3.
IPR004710. Bilac:Na_transpt.
IPR030208. SLC10A1.
[Graphical view]
PANTHERiPTHR10361. PTHR10361. 1 hit.
PTHR10361:SF40. PTHR10361:SF40. 1 hit.
PfamiPF01758. SBF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00841. bass. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO35940_MOUSE
AccessioniPrimary (citable) accession number: O35940
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: June 8, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.