Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Na/taurocholate cotransporting polypeptide 2

Gene

Slc10a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

BRENDAi2.7.1.137 3474

Names & Taxonomyi

Protein namesi
Submitted name:
Na/taurocholate cotransporting polypeptide 2Imported
Submitted name:
Sodium/bile acid cotransporterImported
Submitted name:
Solute carrier family 10 (Sodium/bile acid cotransporter family), member 1, isoform CRA_dImported
Gene namesi
Name:Slc10a1Imported
Synonyms:NtcpImported
ORF Names:mCG_7625Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:97379 Slc10a1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei26 – 48HelicalSequence analysisAdd BLAST23
Transmembranei60 – 79HelicalSequence analysisAdd BLAST20
Transmembranei118 – 142HelicalSequence analysisAdd BLAST25
Transmembranei154 – 176HelicalSequence analysisAdd BLAST23
Transmembranei188 – 208HelicalSequence analysisAdd BLAST21
Transmembranei228 – 246HelicalSequence analysisAdd BLAST19
Transmembranei287 – 308HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG2718 Eukaryota
COG0385 LUCA
GeneTreeiENSGT00550000074505
HOVERGENiHBG101123

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR002657 BilAc:Na_symport/Acr3
IPR004710 Bilac:Na_transpt
IPR038770 Na+/solute_symporter_sf
IPR030208 SLC10A1
PANTHERiPTHR10361 PTHR10361, 1 hit
PTHR10361:SF40 PTHR10361:SF40, 1 hit
PfamiView protein in Pfam
PF01758 SBF, 1 hit
TIGRFAMsiTIGR00841 bass, 1 hit

Sequencei

Sequence statusi: Complete.

O35940-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAHNVSAPF NFSLPPGFGH RATDTALSVI LVVMLLLIML SLGCTMEFSK
60 70 80 90 100
IKAHFWKPKG VIIAIVAQYG IMPLSAFLLG KVFHLTSIEA LAILICGCSP
110 120 130 140 150
GGNLSNLFTL AMKGDMNLSI VMTTCSSFTA LGMMPLLLYI YSKGIYDGDL
160 170 180 190 200
KDKVPYKGIM LSLVMVLIPC AIGIFLKSKR PHYVPYVLKA GMIITFSLSV
210 220 230 240 250
AVTVLSVINV GNSIMFVMTP HLLATSSLMP FTGFLMGYIL SALFRLNPSC
260 270 280 290 300
RRTISMETGF QNVQLCSTIL NVTFPPEVIG PLFFFPLLYM IFQLAEGLLF
310
IIIFRCYLKI KPQKGKY
Length:317
Mass (Da):34,886
Last modified:January 1, 1998 - v1
Checksum:iDA32C829C8A8E6D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125092 Genomic DNA No translation available.
U95132 mRNA Translation: AAB81024.1
CH466590 Genomic DNA Translation: EDL02698.1
RefSeqiNP_035517.1, NM_011387.2
UniGeneiMm.486361

Genome annotation databases

EnsembliENSMUST00000218342; ENSMUSP00000151215; ENSMUSG00000021135
GeneIDi20493
UCSCiuc007obs.2 mouse

Similar proteinsi

Entry informationi

Entry nameiO35940_MOUSE
AccessioniPrimary (citable) accession number: O35940
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health