Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Heat shock protein beta-2

Gene

Hspb2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May regulate the kinase DMPK.By similarity

GO - Molecular functioni

GO - Biological processi

  • response to heat Source: RGD
  • somatic muscle development Source: Ensembl

Keywordsi

Biological processStress response

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock protein beta-2
Short name:
HspB2
Gene namesi
Name:Hspb2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi70914. Hspb2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001259351 – 182Heat shock protein beta-2Add BLAST182

Proteomic databases

PaxDbiO35878.

PTM databases

iPTMnetiO35878.
PhosphoSitePlusiO35878.

Expressioni

Gene expression databases

BgeeiENSRNOG00000010402.
GenevisibleiO35878. RN.

Interactioni

Subunit structurei

Interacts with DMPK; may enhance its kinase activity.By similarity

Protein-protein interaction databases

CORUMiO35878.
STRINGi10116.ENSRNOP00000013960.

Structurei

3D structure databases

ProteinModelPortaliO35878.
SMRiO35878.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 163sHSPPROSITE-ProRule annotationAdd BLAST109

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3591. Eukaryota.
ENOG410YERS. LUCA.
GeneTreeiENSGT00760000119238.
HOGENOMiHOG000233954.
HOVERGENiHBG054766.
InParanoidiO35878.
KOiK09543.
OMAiHGYYIRP.
OrthoDBiEOG091G0USC.
PhylomeDBiO35878.
TreeFamiTF105049.

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiView protein in InterPro
IPR002068. A-crystallin/Hsp20_dom.
IPR001436. Alpha-crystallin/HSP.
IPR003090. Alpha-crystallin_N.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiView protein in Pfam
PF00525. Crystallin. 1 hit.
PF00011. HSP20. 1 hit.
PRINTSiPR00299. ACRYSTALLIN.
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiView protein in PROSITE
PS01031. SHSP. 1 hit.

Sequencei

Sequence statusi: Complete.

O35878-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRTVPHAH PATAEYEFAN PSRLGEQRFG EGLLPEEILT PTLYHGYYVR
60 70 80 90 100
PRAARAGEGG RAGASELRLS EGKFQAFLDV SHFTPDEVTV RTVDNLLEVS
110 120 130 140 150
ARHPQRLDRH GFVSREFCRT YVLPADVDPW RVRAALSHDG ILNLEAPRGG
160 170 180
RHLDTEVNEV YISLLPAPPD PEEEEEVARV EP
Length:182
Mass (Da):20,347
Last modified:January 1, 1998 - v1
Checksum:i4547E53EED9AEA39
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U75899 Genomic DNA. Translation: AAB82758.1.
RefSeqiNP_569115.1. NM_130431.1.
UniGeneiRn.22486.

Genome annotation databases

EnsembliENSRNOT00000013960; ENSRNOP00000013960; ENSRNOG00000010402.
GeneIDi161476.
KEGGirno:161476.
UCSCiRGD:70914. rat.

Similar proteinsi

Entry informationi

Entry nameiHSPB2_RAT
AccessioniPrimary (citable) accession number: O35878
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 1, 1998
Last modified: September 27, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families