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Protein

Sex-determining region Y protein

Gene

Sry

Organism
Mus musculus castaneus (Southeastern Asian house mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi5 – 73HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorSAAS annotation, Calmodulin-bindingSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processDifferentiation, Sexual differentiationSAAS annotation, Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Sex-determining region Y proteinSAAS annotation
Gene namesi
Name:SryImported
OrganismiMus musculus castaneus (Southeastern Asian house mouse)Imported
Taxonomic identifieri10091 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliO35863.
SMRiO35863.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 73HMG boxInterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the SRY family.SAAS annotation

Phylogenomic databases

HOVERGENiHBG008712.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiView protein in InterPro
IPR009071. HMG_box_dom.
IPR036910. HMG_box_dom_sf.
IPR017253. SRY.
PANTHERiPTHR10270:SF199. PTHR10270:SF199. 5 hits.
PfamiView protein in Pfam
PF00505. HMG_box. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 1 hit.
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

O35863-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE
60 70 80 90 100
KRPFFQEAQR LKTLHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN
110 120 130 140 150
LLQWDRNPHA ITYRQDWSRA AHLYSKNQQS FYWQPVDIPT GHLQQQQQQQ
160 170 180 190 200
QQQQFHNHHQ QQQQFYDHHH HQQQQQQQQQ QQQFHDHHQQ KQQFHDHHQQ
210 220 230 240 250
QQQFHDHHHH HQEQQFHDHH QQQQQFHDHH QQQQQQQQQQ FHDHHQQKQQ
260 270 280 290 300
FHDHHHHQQQ QQFHDHQQQQ QQFHDHQQQQ HQFHDHPQQK QQFHDHPQQQ
310 320 330 340 350
QQFHDHHHQQ QQKQQFHDHH QQKQQFHDHH QQKQQFHDHH QQQQQFHDHQ
360 370 380 390
QQQQQQQQQQ QQQQQFHDQQ LTYLLTADIA GEHTPYQEHL STALWLAVS
Length:399
Mass (Da):49,983
Last modified:January 1, 1998 - v1
Checksum:i92BD954750434DE5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70657 Genomic DNA. Translation: AAC53447.1.
UniGeneiMm.377114.

Similar proteinsi

Entry informationi

Entry nameiO35863_MUSMC
AccessioniPrimary (citable) accession number: O35863
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: October 25, 2017
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)