O35843 (O35843_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Bcl-x-gamma EMBL AAC53458.1

Gene names

Name:	Bcl2l1 MGI 88139
Synonyms:	Bcl2l MGI 88139

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	235 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	cell proliferation Inferred from direct assay PubMed 9176392. Source: MGI cellular process regulating host cell cycle in response to virus Inferred from mutant phenotype PubMed 15231831. Source: MGI cellular response to alkaloid Inferred from direct assay PubMed 15231831. Source: MGI cellular response to amino acid stimulus Inferred from mutant phenotype PubMed 15231831. Source: MGI cellular response to gamma radiation Inferred from mutant phenotype PubMed 15231831. Source: MGI fertilization Inferred from genetic interaction PubMed 10894153. Source: MGI germ cell development Inferred from mutant phenotype PubMed 10894153. Source: MGI growth Inferred from mutant phenotype PubMed 10894153. Source: MGI in utero embryonic development Inferred from mutant phenotype PubMed 10618441. Source: MGI male gonad development Inferred from mutant phenotype PubMed 10894153. Source: MGI negative regulation of neuron apoptotic process Inferred from direct assay PubMed 15231831PubMed 7753802PubMed 8625820. Source: MGI ovarian follicle development Inferred from mutant phenotype PubMed 10894153. Source: MGI positive regulation of apoptotic process Inferred from direct assay PubMed 8798158. Source: MGI positive regulation of cell proliferation Inferred from direct assay PubMed 17267035. Source: MGI release of cytochrome c from mitochondria Inferred from genetic interaction PubMed 17052454. Source: MGI response to cycloheximide Inferred from direct assay PubMed 9176392. Source: MGI response to cytokine stimulus Inferred from sequence orthology PubMed 9184696. Source: MGI spermatogenesis Inferred from genetic interaction PubMed 10894153. Source: MGI
Cellular_component	cytosol Inferred from direct assay PubMed 11980919. Source: MGI mitochondrial membrane Inferred from direct assay PubMed 11980919. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O35843 [UniParc]. Last modified January 1, 1998. Version 1. Checksum: 649D914C2D5378F6	FASTA	235	26,122
	10 20 30 40 50 60 MSQSNRELVV DFLSYKLSQK GYSWSQFSDV EENRTEAPEE TEAERETPSA INGNPSWHLA 70 80 90 100 110 120 DSPAVNGATG HSSSLDAREV IPMAAVKQAL REAGDEFELR YRRAFSDLTS QLHITPGTAY 130 140 150 160 170 180 QSFEQVVNEL FRDGVNWGRI VAFFSFGGAL CVESVDKEMQ VLVSRIASWM ATYLNDHLEP 190 200 210 220 230 WIQENGGWGV SGGTPLRSVF RRLVQVPGVA EHVCDPSLWE VETEGSEVQG PPQLL

References

[1]	"A novel Bcl-x isoform connected to the T cell receptor regulates apoptosis in T cells." Yang X.-F., Weber G.F., Cantor H. Immunity 7:629-639(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: B6/CBA EMBL AAC53458.1. Tissue: Thymus EMBL AAC53458.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U51277 mRNA. Translation: AAC53458.1.
IPI	IPI00474590.
UniGene	Mm.238213.
3D structure databases
HSSP	HSSP built from PDB template 1AF3 based on UniProtKB P53563.
ProteinModelPortal	O35843.
SMR	O35843. Positions 1-188.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000086454. O35843.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:88139. Bcl2l1.
Phylogenomic databases
HOGENOM	HOG000056452.
HOVERGEN	HBG004472.
InParanoid	O35843.
Gene expression databases
ArrayExpress	O35843.
Bgee	O35843.
Genevestigator	O35843.
Family and domain databases
InterPro	IPR013279. Apop_reg_BclX. IPR002475. Bcl2-like. IPR020717. Bcl2_BH1_motif_CS. IPR020728. Bcl2_BH3_motif_CS. IPR003093. Bcl2_BH4. IPR020731. Bcl2_BH4_motif_CS. IPR026298. Blc2_fam. [Graphical view]
PANTHER	PTHR11256. PTHR11256. 1 hit. PTHR11256:SF12. PTHR11256:SF12. 1 hit.
Pfam	PF00452. Bcl-2. 1 hit. PF02180. BH4. 1 hit. [Graphical view]
PRINTS	PR01864. APOPREGBCLX. PR01862. BCL2FAMILY.
SMART	SM00265. BH4. 1 hit. [Graphical view]
PROSITE	PS50062. BCL2_FAMILY. 1 hit. PS01080. BH1. 1 hit. PS01259. BH3. 1 hit. PS01260. BH4_1. 1 hit. PS50063. BH4_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	BCL2L1. mouse.
SOURCE	Search...

Entry information

Entry name

O35843_MOUSE

Accession

Primary (citable) accession number: O35843

Entry history

Integrated into UniProtKB/TrEMBL:	January 1, 1998
Last sequence update:	January 1, 1998
Last modified:	April 3, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)