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Protein
Submitted name:

GDNFR-alpha/TrnR1-delta protein

Gene

Gfra1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
GDNFR-alpha/TrnR1-delta proteinImported
Submitted name:
Glial cell line derived neurotrophic factor family receptor alpha 1, isoform CRA_bImported
Gene namesi
Name:Gfra1Imported
ORF Names:rCG_57678Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi2681. Gfra1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 463439Sequence analysisPRO_5005360042Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023667.

Structurei

3D structure databases

ProteinModelPortaliO35748.
SMRiO35748. Positions 234-341.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini29 – 11183GDNFInterPro annotationAdd
BLAST
Domaini149 – 22880GDNFInterPro annotationAdd
BLAST
Domaini238 – 33295GDNFInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IU4F. Eukaryota.
ENOG410XPTA. LUCA.
HOGENOMiHOG000008695.
HOVERGENiHBG051725.
OrthoDBiEOG7FBRJ3.

Family and domain databases

InterProiIPR016017. GDNF/GAS1.
IPR003438. GDNF_rcpt.
IPR003503. GDNF_rcpt_A1.
IPR017372. Glial_neurotroph_fac_rcpt_a1/2.
[Graphical view]
PfamiPF02351. GDNF. 3 hits.
[Graphical view]
PIRSFiPIRSF038071. GDNF_family_receptor_alpha. 1 hit.
PRINTSiPR01317. GDNFRALPHA1.
PR01316. GDNFRECEPTOR.
SMARTiSM00907. GDNF. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O35748-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLATLYFAL PLLDLLMSAE VSGGDRLDCV KASDQCLKEQ SCSTKYRTLR
60 70 80 90 100
QCVAGKETNF SLTSGLEAKD ECRSAMEALK QKSLYNCRCK RGMKKEKNCL
110 120 130 140 150
RIYWSMYQSL QGNDLLEDSP YEPVNSRLSD IFRAVPFISV EHISKGNNCL
160 170 180 190 200
DAAKACNLDD TCKKYRSAYI TPCTTSMSNE VCNRRKCHKA LRQFFDKVPA
210 220 230 240 250
KHSYGMLFCS CRDIACTERR RQTIVPVCSY EERERPNCLS LQDSCKTNYI
260 270 280 290 300
CRSRLADFFT NCQPESRSVS NCLKENYADC LLAYSGLIGT VMTPNYVDSS
310 320 330 340 350
SLSVAPWCDC SNSGNDLEDC LKFLNFFKDN TCLKNAIQAF GNGSDVTMWQ
360 370 380 390 400
PAPPVQTTTA TTTTAFRVKN KPLGPAGSEN EIPTHVLPPC ANLQAQKLKS
410 420 430 440 450
NVSGSTHLCL SDSDFGKDGL AGASSHITTK SMAAPPSCSL SSLPVLMLTA
460
LAALLSVSLA ETS
Length:463
Mass (Da):51,032
Last modified:January 1, 1998 - v1
Checksum:iCCC9583ACE7353CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002072 mRNA. Translation: CAA05171.1.
CH473986 Genomic DNA. Translation: EDL94531.1.
CH473986 Genomic DNA. Translation: EDL94532.1.
CH473986 Genomic DNA. Translation: EDL94533.1.
PIRiS69080.
RefSeqiXP_008758736.1. XM_008760514.1.
UniGeneiRn.88489.

Genome annotation databases

GeneIDi25454.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ002072 mRNA. Translation: CAA05171.1.
CH473986 Genomic DNA. Translation: EDL94531.1.
CH473986 Genomic DNA. Translation: EDL94532.1.
CH473986 Genomic DNA. Translation: EDL94533.1.
PIRiS69080.
RefSeqiXP_008758736.1. XM_008760514.1.
UniGeneiRn.88489.

3D structure databases

ProteinModelPortaliO35748.
SMRiO35748. Positions 234-341.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000023667.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi25454.

Organism-specific databases

CTDi2674.
RGDi2681. Gfra1.

Phylogenomic databases

eggNOGiENOG410IU4F. Eukaryota.
ENOG410XPTA. LUCA.
HOGENOMiHOG000008695.
HOVERGENiHBG051725.
OrthoDBiEOG7FBRJ3.

Family and domain databases

InterProiIPR016017. GDNF/GAS1.
IPR003438. GDNF_rcpt.
IPR003503. GDNF_rcpt_A1.
IPR017372. Glial_neurotroph_fac_rcpt_a1/2.
[Graphical view]
PfamiPF02351. GDNF. 3 hits.
[Graphical view]
PIRSFiPIRSF038071. GDNF_family_receptor_alpha. 1 hit.
PRINTSiPR01317. GDNFRALPHA1.
PR01316. GDNFRECEPTOR.
SMARTiSM00907. GDNF. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Rattus norvegicus GDNFR-alpha/TrnR1-delta mRNA, complete cds."
    Zhong J., Annies M., Heumann R.
    Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HannoverImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.

Entry informationi

Entry nameiO35748_RAT
AccessioniPrimary (citable) accession number: O35748
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: February 17, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.