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O35739 (KLF9_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 110. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Krueppel-like factor 9
Alternative name(s):
Basic transcription element-binding protein 1
Short name=BTE-binding protein 1
GC-box-binding protein 1
Transcription factor BTEB1
Gene names
Name:Klf9
Synonyms:Bteb, Bteb-1, Bteb1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length244 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box.

Subcellular location

Nucleus.

Sequence similarities

Belongs to the Sp1 C2H2-type zinc-finger protein family.

Contains 3 C2H2-type zinc fingers.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 244244Krueppel-like factor 9
PRO_0000047155

Regions

Zinc finger143 – 16725C2H2-type 1
Zinc finger173 – 19725C2H2-type 2
Zinc finger203 – 22523C2H2-type 3
Compositional bias84 – 11633Asp/Glu-rich (acidic)

Sequences

Sequence LengthMass (Da)Tools
O35739 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: BBDF607FFA218D5A

FASTA24427,170
        10         20         30         40         50         60 
MSAAAYMDFV AAQCLVSISN RAAVPEHGGA PEAERLRLPE REVTKEHGDP GDTWKDYCTL 

        70         80         90        100        110        120 
VTIAKSLLDL NKYRPIQTPS VCSDSLESPD EDIGSDSDVT TESGSSPSHS PEERQDSGSA 

       130        140        150        160        170        180 
PSPLSLLHSG VASKGKHASE KRHKCPYSGC GKVYGKSSHL KAHYRVHTGE RPFPCTWPDC 

       190        200        210        220        230        240 
LKKFSRSDEL TRHYRTHTGE KQFRCPLCEK RFMRSDHLTK HARRHTVFHP SMIKRSKKAL 


ACPL 

« Hide

References

[1]"Transcriptional regulation of the AP-2alpha promoter by BTEB-1 and AP-2rep, a novel wt-1/egr-related zinc finger repressor."
Imhof A., Schuierer M., Werner O., Moser M., Roth C., Bauer R., Buettner R.
Mol. Cell. Biol. 19:194-204(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: BALB/c.
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y14296 mRNA. Translation: CAA74671.1.
CCDSCCDS29706.1.
UniGeneMm.291595.
Mm.392684.

3D structure databases

ProteinModelPortalO35739.
SMRO35739. Positions 76-110, 140-225.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000045639.

PTM databases

PhosphoSiteO35739.

Proteomic databases

PRIDEO35739.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:1333856. Klf9.

Phylogenomic databases

eggNOGCOG5048.
HOGENOMHOG000233575.
HOVERGENHBG050746.
InParanoidO35739.
PhylomeDBO35739.

Gene expression databases

CleanExMM_KLF9.
GenevestigatorO35739.

Family and domain databases

Gene3D3.30.160.60. 3 hits.
InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 3 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 3 hits.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSKLF9. mouse.
PROO35739.
SOURCESearch...

Entry information

Entry nameKLF9_MOUSE
AccessionPrimary (citable) accession number: O35739
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot