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O35683 (NDUA1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Alternative name(s):
Complex I-MWFE
Short name=CI-MWFE
NADH-ubiquinone oxidoreductase MWFE subunit
Gene names
Name:Ndufa1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length70 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.

Subunit structure

Complex I is composed of 45 different subunits By similarity.

Subcellular location

Mitochondrion inner membrane; Single-pass membrane protein; Matrix side By similarity.

Sequence similarities

Belongs to the complex I NDUFA1 subunit family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7070NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
PRO_0000118818

Regions

Transmembrane1 – 2121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O35683 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 58CB30E72A275734

FASTA708,139
        10         20         30         40         50         60 
MWFEILPGLA IMGVCLVIPG VSTAYIHKFT NGGKEKRVAR VQYQWYLMER DRRISGVNRY 

        70 
YVSKGLENID 

« Hide

References

« Hide 'large scale' references
[1]Frattini A., Faranda S., Bagnasco L., Patrosso C., Nulli P., Vezzoni P.
Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Mammary gland.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y07708 mRNA. Translation: CAA68977.1.
BC024364 mRNA. Translation: AAH24364.1.
RefSeqNP_062316.1. NM_019443.2.
UniGeneMm.34869.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000016571.

PTM databases

PhosphoSiteO35683.

Proteomic databases

PaxDbO35683.
PRIDEO35683.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000016571; ENSMUSP00000016571; ENSMUSG00000016427.
GeneID54405.
KEGGmmu:54405.
UCSCuc009syi.1. mouse.

Organism-specific databases

CTD4694.
MGIMGI:1929511. Ndufa1.

Phylogenomic databases

eggNOGNOG79354.
HOGENOMHOG000010206.
HOVERGENHBG000813.
InParanoidO35683.
KOK03945.
OMAWYLMERD.
OrthoDBEOG7NGQFC.
PhylomeDBO35683.
TreeFamTF333394.

Gene expression databases

ArrayExpressO35683.
BgeeO35683.
GenevestigatorO35683.

Family and domain databases

InterProIPR017384. NADH_Ub_cplx-1_asu_su-1.
[Graphical view]
PANTHERPTHR17098. PTHR17098. 1 hit.
PIRSFPIRSF038095. NDUA1. 1 hit.
ProtoNetSearch...

Other

ChiTaRSNDUFA1. mouse.
NextBio311272.
PROO35683.
SOURCESearch...

Entry information

Entry nameNDUA1_MOUSE
AccessionPrimary (citable) accession number: O35683
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: April 16, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot