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O35680 (RT12_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 112. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
28S ribosomal protein S12, mitochondrial

Short name=MRP-S12
Short name=S12mt
Alternative name(s):
MT-RPS12
Gene names
Name:Mrps12
Synonyms:Rpms12
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length139 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subunit structure

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Subcellular location

Mitochondrion.

Sequence similarities

Belongs to the ribosomal protein S12P family.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentmitochondrion

Inferred from direct assay PubMed 14651853PubMed 18614015. Source: MGI

small ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionstructural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 2929Mitochondrion Potential
Chain30 – 13911028S ribosomal protein S12, mitochondrial
PRO_0000030607

Sequences

Sequence LengthMass (Da)Tools
O35680 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: B365FE940025EA08

FASTA13915,437
        10         20         30         40         50         60 
MSWPGLLYGL TTSLSRGLAL APQLWAARSM ATLNQMHRLG PRKEPPKRLG PTEGRPQLKG 

        70         80         90        100        110        120 
VVLRTFIRKP KKPNSANRKC CRVRLSTGKE AVCFIPGEGH TLQEHHVVLV EGGRTQDLPG 

       130 
VKLKVVRGKY DCGHVQKKK 

« Hide

References

« Hide 'large scale' references
[1]"Metazoan nuclear genes for mitoribosomal protein S12."
Shah Z.H., O'Dell K.M., Miller S.C.M., An X., Jacobs H.T.
Gene 204:55-62(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: C57BL/6J.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Czech II and FVB/N.
Tissue: Colon and Lung.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y11682 mRNA. Translation: CAA72378.1.
BC012679 mRNA. Translation: AAH12679.1.
BC027522 mRNA. Translation: AAH27522.1.
CCDSCCDS21052.1.
RefSeqNP_036015.1. NM_011885.4.
XP_006539971.1. XM_006539908.1.
UniGeneMm.358650.

3D structure databases

ProteinModelPortalO35680.
SMRO35680. Positions 26-139.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000062066.

PTM databases

PhosphoSiteO35680.

Proteomic databases

PaxDbO35680.
PRIDEO35680.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000056078; ENSMUSP00000062066; ENSMUSG00000045948.
ENSMUST00000171183; ENSMUSP00000132443; ENSMUSG00000045948.
GeneID24030.
KEGGmmu:24030.
UCSCuc009fzo.1. mouse.

Organism-specific databases

CTD6183.
MGIMGI:1346333. Mrps12.

Phylogenomic databases

eggNOGCOG0048.
GeneTreeENSGT00550000075103.
HOGENOMHOG000040063.
HOVERGENHBG001525.
InParanoidO35680.
KOK02950.
OMALNQMHRR.
OrthoDBEOG7Z69F2.
PhylomeDBO35680.
TreeFamTF315095.

Gene expression databases

ArrayExpressO35680.
BgeeO35680.
CleanExMM_MRPS12.
GenevestigatorO35680.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
InterProIPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view]
PANTHERPTHR11652. PTHR11652. 1 hit.
PfamPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSPR01034. RIBOSOMALS12.
SUPFAMSSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00981. rpsL_bact. 1 hit.
PROSITEPS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio303963.
PROO35680.
SOURCESearch...

Entry information

Entry nameRT12_MOUSE
AccessionPrimary (citable) accession number: O35680
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: July 9, 2014
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot