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O35680

- RT12_MOUSE

UniProt

O35680 - RT12_MOUSE

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Protein

28S ribosomal protein S12, mitochondrial

Gene

Mrps12

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: Ensembl
  2. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S12, mitochondrial
Short name:
MRP-S12
Short name:
S12mt
Alternative name(s):
MT-RPS12
Gene namesi
Name:Mrps12
Synonyms:Rpms12
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 7

Organism-specific databases

MGIiMGI:1346333. Mrps12.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: MGI
  2. small ribosomal subunit Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2929MitochondrionSequence AnalysisAdd
BLAST
Chaini30 – 13911028S ribosomal protein S12, mitochondrialPRO_0000030607Add
BLAST

Proteomic databases

MaxQBiO35680.
PaxDbiO35680.
PRIDEiO35680.

PTM databases

PhosphoSiteiO35680.

Expressioni

Gene expression databases

BgeeiO35680.
CleanExiMM_MRPS12.
ExpressionAtlasiO35680. baseline and differential.
GenevestigatoriO35680.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062066.

Structurei

3D structure databases

ProteinModelPortaliO35680.
SMRiO35680. Positions 31-139.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S12P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0048.
GeneTreeiENSGT00550000075103.
HOGENOMiHOG000040063.
HOVERGENiHBG001525.
InParanoidiO35680.
KOiK02950.
OMAiLNQMHRR.
OrthoDBiEOG7Z69F2.
PhylomeDBiO35680.
TreeFamiTF315095.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view]
PANTHERiPTHR11652. PTHR11652. 1 hit.
PfamiPF00164. Ribosom_S12_S23. 1 hit.
[Graphical view]
PIRSFiPIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSiPR01034. RIBOSOMALS12.
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00981. rpsL_bact. 1 hit.
PROSITEiPS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O35680-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSWPGLLYGL TTSLSRGLAL APQLWAARSM ATLNQMHRLG PRKEPPKRLG
60 70 80 90 100
PTEGRPQLKG VVLRTFIRKP KKPNSANRKC CRVRLSTGKE AVCFIPGEGH
110 120 130
TLQEHHVVLV EGGRTQDLPG VKLKVVRGKY DCGHVQKKK
Length:139
Mass (Da):15,437
Last modified:January 1, 1998 - v1
Checksum:iB365FE940025EA08
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y11682 mRNA. Translation: CAA72378.1.
BC012679 mRNA. Translation: AAH12679.1.
BC027522 mRNA. Translation: AAH27522.1.
CCDSiCCDS21052.1.
RefSeqiNP_036015.1. NM_011885.4.
XP_006539971.1. XM_006539908.1.
UniGeneiMm.358650.

Genome annotation databases

EnsembliENSMUST00000056078; ENSMUSP00000062066; ENSMUSG00000045948.
ENSMUST00000171183; ENSMUSP00000132443; ENSMUSG00000045948.
GeneIDi24030.
KEGGimmu:24030.
UCSCiuc009fzo.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Y11682 mRNA. Translation: CAA72378.1 .
BC012679 mRNA. Translation: AAH12679.1 .
BC027522 mRNA. Translation: AAH27522.1 .
CCDSi CCDS21052.1.
RefSeqi NP_036015.1. NM_011885.4.
XP_006539971.1. XM_006539908.1.
UniGenei Mm.358650.

3D structure databases

ProteinModelPortali O35680.
SMRi O35680. Positions 31-139.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000062066.

PTM databases

PhosphoSitei O35680.

Proteomic databases

MaxQBi O35680.
PaxDbi O35680.
PRIDEi O35680.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000056078 ; ENSMUSP00000062066 ; ENSMUSG00000045948 .
ENSMUST00000171183 ; ENSMUSP00000132443 ; ENSMUSG00000045948 .
GeneIDi 24030.
KEGGi mmu:24030.
UCSCi uc009fzo.1. mouse.

Organism-specific databases

CTDi 6183.
MGIi MGI:1346333. Mrps12.

Phylogenomic databases

eggNOGi COG0048.
GeneTreei ENSGT00550000075103.
HOGENOMi HOG000040063.
HOVERGENi HBG001525.
InParanoidi O35680.
KOi K02950.
OMAi LNQMHRR.
OrthoDBi EOG7Z69F2.
PhylomeDBi O35680.
TreeFami TF315095.

Miscellaneous databases

NextBioi 303963.
PROi O35680.
SOURCEi Search...

Gene expression databases

Bgeei O35680.
CleanExi MM_MRPS12.
ExpressionAtlasi O35680. baseline and differential.
Genevestigatori O35680.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
InterProi IPR012340. NA-bd_OB-fold.
IPR006032. Ribosomal_S12/S23.
IPR005679. Ribosomal_S12_bac.
[Graphical view ]
PANTHERi PTHR11652. PTHR11652. 1 hit.
Pfami PF00164. Ribosom_S12_S23. 1 hit.
[Graphical view ]
PIRSFi PIRSF002133. Ribosomal_S12/S23. 1 hit.
PRINTSi PR01034. RIBOSOMALS12.
SUPFAMi SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00981. rpsL_bact. 1 hit.
PROSITEi PS00055. RIBOSOMAL_S12. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Metazoan nuclear genes for mitoribosomal protein S12."
    Shah Z.H., O'Dell K.M., Miller S.C.M., An X., Jacobs H.T.
    Gene 204:55-62(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Czech II and FVB/N.
    Tissue: Colon and Lung.

Entry informationi

Entry nameiRT12_MOUSE
AccessioniPrimary (citable) accession number: O35680
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: October 29, 2014
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3