##gff-version 3 O35615 UniProtKB Chain 1 995 . . . ID=PRO_0000221042;Note=Zinc finger protein ZFPM1 O35615 UniProtKB Zinc finger 249 282 . . . Note=CCHC FOG-type 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Zinc finger 303 327 . . . Note=C2H2-type 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042 O35615 UniProtKB Zinc finger 333 355 . . . Note=C2H2-type 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042 O35615 UniProtKB Zinc finger 361 384 . . . Note=C2H2-type 3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042 O35615 UniProtKB Zinc finger 584 617 . . . Note=CCHC FOG-type 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Zinc finger 690 723 . . . Note=CCHC FOG-type 3;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Zinc finger 830 863 . . . Note=CCHC FOG-type 4;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Zinc finger 868 891 . . . Note=C2H2-type 4;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00042 O35615 UniProtKB Zinc finger 957 990 . . . Note=CCHC FOG-type 5;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Region 1 103 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Region 343 354 . . . Note=Interaction with TACC3;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Region 424 526 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Region 616 694 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Region 721 827 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Region 811 817 . . . Note=Interaction with CTBP2 O35615 UniProtKB Region 892 960 . . . Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Compositional bias 11 40 . . . Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Compositional bias 42 67 . . . Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Compositional bias 77 96 . . . Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Compositional bias 438 462 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Compositional bias 500 519 . . . Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Compositional bias 724 744 . . . Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Compositional bias 765 786 . . . Note=Pro residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite O35615 UniProtKB Binding site 257 257 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 260 260 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 273 273 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 278 278 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 592 592 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 595 595 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 608 608 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 613 613 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 698 698 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 701 701 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 714 714 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 719 719 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 838 838 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 841 841 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 854 854 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 859 859 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 965 965 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 968 968 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 981 981 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Binding site 986 986 . . . Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01153 O35615 UniProtKB Modified residue 99 99 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8IX07 O35615 UniProtKB Modified residue 143 143 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 O35615 UniProtKB Modified residue 286 286 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 O35615 UniProtKB Modified residue 397 397 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8IX07 O35615 UniProtKB Modified residue 497 497 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 O35615 UniProtKB Modified residue 500 500 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 O35615 UniProtKB Modified residue 651 651 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8IX07 O35615 UniProtKB Modified residue 684 684 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8IX07 O35615 UniProtKB Modified residue 803 803 . . . Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8IX07 O35615 UniProtKB Modified residue 822 822 . . . Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079 O35615 UniProtKB Modified residue 925 925 . . . Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:17242355,ECO:0007744|PubMed:21183079;Dbxref=PMID:17242355,PMID:21183079 O35615 UniProtKB Modified residue 927 927 . . . Note=Phosphoserine;Ontology_term=ECO:0007744,ECO:0007744;evidence=ECO:0007744|PubMed:17242355,ECO:0007744|PubMed:21183079;Dbxref=PMID:17242355,PMID:21183079 O35615 UniProtKB Mutagenesis 254 254 . . . Note=Does not affect the interaction with GATA1. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 255 255 . . . Note=Impairs interaction with GATA1. F->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 256 256 . . . Note=Does not affect the interaction with GATA1. P->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 258 258 . . . Note=Does not affect the interaction with GATA1. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 259 259 . . . Note=Does not affect the interaction with GATA1. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 261 261 . . . Note=Slightly affects the interaction with GATA1. G->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 262 262 . . . Note=Impairs interaction with GATA1. I->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 263 263 . . . Note=Does not affect the interaction with GATA1. W->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 265 265 . . . Note=Slightly affects the interaction with GATA1. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 266 266 . . . Note=Does not affect the interaction with GATA1. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 267 267 . . . Note=Slightly affects the interaction with GATA1. E->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 268 268 . . . Note=Does not affect the interaction with GATA1. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 269 269 . . . Note=Impairs interaction with GATA1. N->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 271 271 . . . Note=Does not affect the interaction with GATA1. Q->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 274 274 . . . Note=Slightly affects the interaction with GATA1. L->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 275 275 . . . Note=Does not affect the interaction with GATA1. L->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 276 276 . . . Note=Slightly affects the interaction with GATA1. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 277 277 . . . Note=Impairs interaction with GATA1. Strongly impairs interaction with GATA1%3B when associated with A-612%3B A-718 and/or A-985. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 280 280 . . . Note=Does not affect the interaction with GATA1. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 281 281 . . . Note=Does not affect the interaction with GATA1. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 334 334 . . . Note=No effect on interaction with TACC3. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 336 336 . . . Note=No effect on interaction with TACC3. L->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 339 339 . . . Note=No effect on interaction with TACC3. L->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 340 340 . . . Note=No effect on interaction with TACC3. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 343 343 . . . Note=Impairs interaction with TACC3. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 344 344 . . . Note=Abolishes interaction with TACC3. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 345 345 . . . Note=No effect on interaction with TACC3. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 346 346 . . . Note=No effect on interaction with TACC3. A->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 347 347 . . . Note=Abolishes interaction with TACC3. N->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 349 349 . . . Note=No effect on interaction with TACC3. E->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 350 350 . . . Note=Abolishes interaction with TACC3. R->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 352 352 . . . Note=No effect on interaction with TACC3. L->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 353 353 . . . Note=No effect on interaction with TACC3. K->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 354 354 . . . Note=Abolishes interaction with TACC3. V->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 356 356 . . . Note=No effect on interaction with TACC3. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 357 357 . . . Note=No effect on interaction with TACC3. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15234987;Dbxref=PMID:15234987 O35615 UniProtKB Mutagenesis 612 612 . . . Note=Impairs interaction with GATA1. Strongly impairs interaction with GATA1%3B when associated with A-277%3B A-718 and/or A-985. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 698 698 . . . Note=Abolishes interaction with GATA1. C->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9837943;Dbxref=PMID:9837943 O35615 UniProtKB Mutagenesis 706 706 . . . Note=Able to partially restore the interaction with the G-205 GATA1 mutant%2C which is usually unable to interact with ZFPM1. S->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10078204;Dbxref=PMID:10078204 O35615 UniProtKB Mutagenesis 718 718 . . . Note=Impairs interaction with GATA1. Strongly impairs interaction with GATA1%3B when associated with A-277%3B A-612 and/or A-985. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 719 719 . . . Note=Abolishes interaction with GATA1. C->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9837943;Dbxref=PMID:9837943 O35615 UniProtKB Mutagenesis 719 719 . . . Note=Transforms the C2HC-type zinc finger into a C2H2-type%2C leading to abolition of interaction with GATA1. C->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:9837943;Dbxref=PMID:9837943 O35615 UniProtKB Mutagenesis 811 814 . . . Note=Abolishes interaction with CTBP2. PIDL->AIAA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Mutagenesis 813 814 . . . Note=Abolishes interaction with CTBP2%3B it however does not abolish the corepressor activity in erythropoiesis. DL->AS;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:11940669;Dbxref=PMID:11940669 O35615 UniProtKB Mutagenesis 985 985 . . . Note=Slightly affects the interaction with GATA1. Strongly impairs interaction with GATA1%3B when associated with A-277%3B A-612 and/or A-718. Y->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10329627;Dbxref=PMID:10329627 O35615 UniProtKB Beta strand 107 112 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2MPL O35615 UniProtKB Beta strand 115 122 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2MPL O35615 UniProtKB Turn 144 146 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2MPL O35615 UniProtKB Helix 162 164 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2MPL O35615 UniProtKB Beta strand 168 182 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2MPL O35615 UniProtKB Beta strand 185 190 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2MPL O35615 UniProtKB Beta strand 201 204 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:2MPL O35615 UniProtKB Beta strand 336 338 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1SRK O35615 UniProtKB Beta strand 341 344 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1SRK O35615 UniProtKB Helix 345 352 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1SRK O35615 UniProtKB Helix 353 355 . . . Ontology_term=ECO:0007829;evidence=ECO:0007829|PDB:1SRK