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Reviewed, UniProtKB/Swiss-Prot O35468 (WNT9B_MOUSE)

Last modified June 16, 2009. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Protein Wnt-9b
Alternative name(s):
    Wnt-15
    Wnt-14b
Gene names
Name: Wnt9b
Synonyms: Wnt14b, Wnt15
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

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Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters By similarity.

Subcellular location

Secreted › extracellular space › extracellular matrix.

Sequence similarities

Belongs to the Wnt family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2323 Potential
Chain24 – 359336Protein Wnt-9b
PRO_0000041459

Amino acid modifications

Glycosylation1011N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict3101D → G in AAC39950. Ref.3

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Sequences

Sequence LengthMass (Da)Tools
O35468-1 [UniParc].

Last modified April 30, 2003. Version 2.
Checksum: C98D7B5F566B70F5

FASTA35938,982
        10         20         30         40         50         60 
MRPAPALALA ALCLLVLPAA AAAAAYFGLT GREVLTPFPG LGTAAAPAQA GAHLKQCDLL 

        70         80         90        100        110        120 
KLSRRQKQLC RREPGLAETL RDAAHLGLLE CQFQFRQERW NCSLEGRTGL LQRGFKETAF 

       130        140        150        160        170        180 
LYAVSAAALT HALARACSAG RMERCTCDDS PGLESRQAWQ WGVCGDNLKY STKFLSNFLG 

       190        200        210        220        230        240 
PKRGSKDLRA RADAHNTHVG IKAVKSGLRT TCKCHGVSGS CAVRTCWKQL SPFRETGQVL 

       250        260        270        280        290        300 
KLRYDTAVKV SSATNEALGR LELWAPAKPG GPAKGLAPRP GDLVYMEDSP SFCRPSKYSP 

       310        320        330        340        350 
GTAGRVCSRD SSCSSLCCGR GYDTQSRMVV FSCHCQVQWC CYVECQQCAQ QELVYTCKR

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References

[1]"Molecular cloning and characterization of mouse Wnt14b, clustered with mouse Wnt3 in mouse chromosome 11."
Kirikoshi H., Katoh M.
Int. J. Mol. Med. 9:135-139(2002) [PubMed: 11786923] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Mouse Wnt9b transforming activity, tissue-specific expression, and evolution."
Qian J., Jiang Z., Li M., Heaphy P., Liu Y.H., Shackleford G.M.
Genomics 81:34-46(2003) [PubMed: 12573259] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: BALB/c.
[3]"Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21."
Bergstein I., Eisenberg L.M., Bhalerao J., Jenkins N.A., Copeland N.G., Osborne M.P., Bowcock A.M., Brown A.M.C.
Genomics 46:450-458(1997) [PubMed: 9441749] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 211-310.
+Additional computationally mapped references.

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Cross-references

Sequence databases

AB073819 mRNA. Translation: BAB83866.1.
AF469004 mRNA. Translation: AAL82385.1.
AF031169 Genomic DNA. Translation: AAC39950.1.
IPIIPI00227770.
UniGeneMm.215161

3D structure databases

ModBaseSearch...

Genome annotation databases

EnsemblENSMUSG00000018486. Mus musculus. [Contig view]

Organism-specific databases

MGIMGI:1197020. Wnt9b.

Phylogenomic databases

HOGENOMO35468.
HOVERGENO35468.
OMAO35468. GLLECQF.

Gene expression databases

ArrayExpressO35468.
BgeeO35468.
CleanExMM_WNT9B.
GermOnlineENSMUSG00000018486. Mus musculus.

Family and domain databases

InterProIPR005816. Wnt_grthfactor.
IPR018161. Wnt_grthfactor_CS.
IPR005817. Wnt_SF.
[Graphical view]
PANTHERPTHR12027. Wnt. 1 hit.
PfamPF00110. wnt. 1 hit.
[Graphical view]
PRINTSPR01349. WNTPROTEIN.
SMARTSM00097. WNT1. 1 hit.
[Graphical view]
PROSITEPS00246. WNT1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

SOURCESearch...

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Entry information

Entry nameWNT9B_MOUSE
AccessionPrimary (citable) accession number: O35468
Secondary accession number(s): Q8VI90
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: April 30, 2003
Last modified: June 16, 2009
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)

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Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents