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Protein
Submitted name:

Protein Vom2r18

Gene

Vom2r18

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Vom2r18Imported
Submitted name:
Putative pheromone receptorImported
Gene namesi
Name:Vom2r18Imported
Synonyms:Go-VN4Imported, LOC100365824Imported, Vom2r17Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 8

Organism-specific databases

RGDi708409. Vom2r18.

Subcellular locationi

  • Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalSequence analysisAdd BLAST20
Transmembranei148 – 170HelicalSequence analysisAdd BLAST23
Transmembranei204 – 224HelicalSequence analysisAdd BLAST21
Transmembranei245 – 262HelicalSequence analysisAdd BLAST18
Transmembranei595 – 618HelicalSequence analysisAdd BLAST24
Transmembranei630 – 653HelicalSequence analysisAdd BLAST24
Transmembranei665 – 689HelicalSequence analysisAdd BLAST25
Transmembranei709 – 728HelicalSequence analysisAdd BLAST20
Transmembranei754 – 777HelicalSequence analysisAdd BLAST24
Transmembranei789 – 809HelicalSequence analysisAdd BLAST21
Transmembranei815 – 837HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

ExpressionAtlasiO35268. differential.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064924.

Structurei

3D structure databases

ProteinModelPortaliO35268.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini595 – 859G_PROTEIN_RECEP_F3_4InterPro annotationAdd BLAST265

Sequence similaritiesi

Belongs to the G-protein coupled receptor 3 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1056. Eukaryota.
ENOG410XR6W. LUCA.
GeneTreeiENSGT00860000133928.
HOGENOMiHOG000232091.
HOVERGENiHBG098472.
OrthoDBiEOG091G02M6.
PhylomeDBiO35268.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR004073. GPCR_3_vmron_rcpt_2.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01535. VOMERONASL2R.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O35268-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRLRAGKNM LTFILLFFLL NIPLFVPSFI YPRCFWSMKK NEYQDRNLGT
60 70 80 90 100
GCMFFILAVQ QPMEKEYFSH ISNIQTPTEN QKYPLTLAFS MNEINNNPDL
110 120 130 140 150
LPNMSLAFTF SEYSCYLESH HKRLFNFSLK NHEILPNFIC TKDIKCGVVL
160 170 180 190 200
TGLSLVTTVT LHIILNNFIF QQFRQLTYGH FHPALCDHEN FPHLYQMASD
210 220 230 240 250
DTSLALALVS FIIHFSWNWI GLAISDNDQG IHFLSYLRRE MEKNTVCFAF
260 270 280 290 300
VNIIPVNMNL YMSRAEVYYS QVMTSSANVV IIYGDTGNTL AVSFRMWDSL
310 320 330 340 350
GIQRLWVTTS QWDVTPFKKD FTFDNGYGTF GFGHRHSEIS GFKYFVQTLN
360 370 380 390 400
PFKYSDEYLV KLEWMYVNCK ILEYNCKSLK NCSFNHSLEW LMTHTFDMAI
410 420 430 440 450
IEGSYEIYNA VYAFAHALHE MTLQNVDNVL LPNYEEQNYN CKMVYSFLSK
460 470 480 490 500
TQFTNPVGDT VNMNQRNKLK EEYDIFYNWN FPQGLGFKVK IGIFSPYFPK
510 520 530 540 550
GQQLHLSENL IEWSTGRIQM PTSVCSADCG PGFRKVWKNG MPACCFDCSP
560 570 580 590 600
CPENEISNET NVELCVQCPE DQYANQEQNH CIHKARIFLS YDEPLGMALS
610 620 630 640 650
LMALCLAALT VVVLGVFVKH HRTPIVKANN CTLTYILLIA LIFCFLCPLF
660 670 680 690 700
FIGHPNSATC ILQQITFGVV FTVAISTVLA KTTTVILAFR VTAPHRMMKY
710 720 730 740 750
FLVSRASNYI IPICTLIQII VCAIWLGASP PSVDIDAQSE HGHIIIACNK
760 770 780 790 800
GSVTAFYCVL GYLACLAFVS FTLAFLSRNL PVTFNEAKSM TFSMLVFCSV
810 820 830 840 850
WVTFLPVYHG TKGKVMVAVE IFSTLASSAG MLGCIFAPKC YTILFRPDRN
860
SLQMIREKSS SHTHIL
Length:866
Mass (Da):98,963
Last modified:January 1, 1998 - v1
Checksum:iB81ABD730B5F8ABC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07068983 Genomic DNA. No translation available.
AF016181 mRNA. Translation: AAC53328.1.
RefSeqiNP_775440.1. NM_173318.1.
UniGeneiRn.10809.

Genome annotation databases

EnsembliENSRNOT00000071544; ENSRNOP00000064924; ENSRNOG00000049092.
GeneIDi286984.
KEGGirno:286984.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07068983 Genomic DNA. No translation available.
AF016181 mRNA. Translation: AAC53328.1.
RefSeqiNP_775440.1. NM_173318.1.
UniGeneiRn.10809.

3D structure databases

ProteinModelPortaliO35268.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064924.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000071544; ENSRNOP00000064924; ENSRNOG00000049092.
GeneIDi286984.
KEGGirno:286984.

Organism-specific databases

CTDi286984.
RGDi708409. Vom2r18.

Phylogenomic databases

eggNOGiKOG1056. Eukaryota.
ENOG410XR6W. LUCA.
GeneTreeiENSGT00860000133928.
HOGENOMiHOG000232091.
HOVERGENiHBG098472.
OrthoDBiEOG091G02M6.
PhylomeDBiO35268.

Gene expression databases

ExpressionAtlasiO35268. differential.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR004073. GPCR_3_vmron_rcpt_2.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01535. VOMERONASL2R.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO35268_RAT
AccessioniPrimary (citable) accession number: O35268
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.