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Protein
Submitted name:

Putative pheromone receptor

Gene

Vmn2r122

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Putative pheromone receptorImported
Gene namesi
Name:Vmn2r122Imported
Synonyms:V2r2Imported, Vmn2r121Imported, VR2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1316661. Vmn2r122.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei542 – 56726HelicalSequence analysisAdd
BLAST
Transmembranei579 – 60022HelicalSequence analysisAdd
BLAST
Transmembranei612 – 63625HelicalSequence analysisAdd
BLAST
Transmembranei656 – 68025HelicalSequence analysisAdd
BLAST
Transmembranei700 – 72425HelicalSequence analysisAdd
BLAST
Transmembranei736 – 75621HelicalSequence analysisAdd
BLAST
Transmembranei762 – 78423HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 808784Sequence analysisPRO_5004158203Add
BLAST

Proteomic databases

PaxDbiO35190.
PRIDEiO35190.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000094553.

Structurei

3D structure databases

ProteinModelPortaliO35190.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini542 – 806265G_PROTEIN_RECEP_F3_4InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 3 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1056. Eukaryota.
ENOG410XR6W. LUCA.
GeneTreeiENSGT00840000130006.
HOGENOMiHOG000232091.
HOVERGENiHBG098472.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR017978. GPCR_3_C.
IPR004073. GPCR_3_vmron_rcpt_2.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01535. VOMERONASL2R.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O35190-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQLCTFTIS LLFLKFSLIL CCWSEPSCFW RIKKSEDNDG DLQRECHFYL
60 70 80 90 100
WKTDEPIEDS FYNYDLSFRI AGSEYELLLV MFFATDEINK NPYLLPNMSL
110 120 130 140 150
MFSIIGGNCH DLLRSLDQEY AQIDGHMNFV NYFCYLDDSC ATGLTGPSWK
160 170 180 190 200
TSLKLAMHSS MPLVFFGPFN PNLRDHDRLP HVHQVAPKDT HLSHGMVSLM
210 220 230 240 250
FHFRWTWIGL VISDDDQGIQ FLSDLREESQ RHGICLAFVN MIPENMQIYM
260 270 280 290 300
TRATIYDTQI MTSSAKVVII YGDMNSTLEA SFRRWEELGA RRIWITTTQW
310 320 330 340 350
DVITNKKDFT LNLFHGTITF AHHKDEIPKF RNFMQTKKTA KYLVDISHTI
360 370 380 390 400
LEWNYFNCSI SKNSSKMGHF TFNNTLQWTA LHNYDMALSD EGYNLYNAVY
410 420 430 440 450
AVAHTYHEYI LQQVESQKKA KPKRYFTACQ QVSSLMKTRV FMNPVGELVN
460 470 480 490 500
MKHRENQCTE YDIFIIWNFP QGLGLKVKVG SYLPCFPKSQ QLHIADDLEW
510 520 530 540 550
AMGGTSVDME QCVRCPDNKY ANLEQTHCLQ RTVSFLAYED PLGMALGCMA
560 570 580 590 600
LSFSAITILV LVTFVKYKDT PIVKANNRIL SYILLISLVF CFLCSLLFIG
610 620 630 640 650
HPDQVTCILQ QTTFGVLFTV SVSTVLAKTI TVVMAFKLTT PGRRMRGMMM
660 670 680 690 700
TGAPKLVIPI CTLIQLVLCG IWLVTSPPFI DRDIQSEHGK IVILCNKGSV
710 720 730 740 750
VAFHVVLGYL GSLALGSFTL AFLARNLPDT FNEAKFLTFS MLVFCSVWIT
760 770 780 790 800
FLPVYHSTRG KVMVVVEVFS ILASSAGLLM CIFVPKCYVI LIRPDSNFIQ

NHKGKLLY
Length:808
Mass (Da):92,573
Last modified:January 1, 1998 - v1
Checksum:iE64B52349586B2F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF011412 mRNA. Translation: AAC53402.1.
UniGeneiMm.377117.
Mm.458976.

Genome annotation databases

UCSCiuc029vcy.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF011412 mRNA. Translation: AAC53402.1.
UniGeneiMm.377117.
Mm.458976.

3D structure databases

ProteinModelPortaliO35190.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000094553.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiO35190.
PRIDEiO35190.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc029vcy.1. mouse.

Organism-specific databases

MGIiMGI:1316661. Vmn2r122.

Phylogenomic databases

eggNOGiKOG1056. Eukaryota.
ENOG410XR6W. LUCA.
GeneTreeiENSGT00840000130006.
HOGENOMiHOG000232091.
HOVERGENiHBG098472.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR017978. GPCR_3_C.
IPR004073. GPCR_3_vmron_rcpt_2.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01535. VOMERONASL2R.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A multigene family encoding a diverse array of putative pheromone receptors in mammals."
    Matsunami H., Buck L.B.
    Cell 90:775-784(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL6/JImported.

Entry informationi

Entry nameiO35190_MOUSE
AccessioniPrimary (citable) accession number: O35190
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 11, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.