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Protein
Submitted name:

ABPA2

Gene

Scgb1b2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
ABPA2Imported
Submitted name:
Androgen-binding proteinImported
Submitted name:
Androgen-binding protein etaImported
Submitted name:
Lacrimal androgen-binding protein etaImported
Submitted name:
Protein Scgb1b2Imported
Gene namesi
Name:Scgb1b2Imported
Synonyms:Abpa2Imported, AbphImported, ApbhImported, Mja1lImported
ORF Names:mCG_1396Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1930867. Scgb1b2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 9370Sequence analysisPRO_5007206755Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000079468.

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410JG59. Eukaryota.
ENOG4111DIV. LUCA.
GeneTreeiENSGT00390000009774.
HOGENOMiHOG000232163.
HOVERGENiHBG051604.
OMAiKEHAAAF.
OrthoDBiEOG7Q2N84.
TreeFamiTF339838.

Family and domain databases

InterProiIPR006178. Allergen_Fel_d_I_chain1.
IPR016126. Secretoglobin.
[Graphical view]
PfamiPF01099. Uteroglobin. 1 hit.
[Graphical view]
PRINTSiPR00827. FELALLERGEN.
SMARTiSM00096. UTG. 1 hit.
[Graphical view]
SUPFAMiSSF48201. SSF48201. 1 hit.
PROSITEiPS51311. SCGB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O35176-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLTGALVIL GATLLLLTSG GDCGICPAIK EDVHLFLFGT PEEYVNYVEK
60 70 80 90
YKDDPETLEN TEKLKICVDR TLTKENKEHA AAFIEKIESS PLC
Length:93
Mass (Da):10,288
Last modified:January 1, 1998 - v1
Checksum:i275AE20714B093A4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei93 – 931Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC158991 Genomic DNA. No translation available.
AF008595 mRNA. Translation: AAB67069.1.
BC115490 mRNA. Translation: AAI15491.1.
BC115491 mRNA. Translation: AAI15492.1.
GU269233 mRNA. Translation: ADB46068.1.
KM014043 Genomic DNA. Translation: AIQ80460.1.
CH466593 Genomic DNA. Translation: EDL23944.1.
RefSeqiNP_065588.1. NM_020563.3.
UniGeneiMm.6205.

Genome annotation databases

EnsembliENSMUST00000080635; ENSMUSP00000079468; ENSMUSG00000062556.
GeneIDi57426.
KEGGimmu:57426.
UCSCiuc009gii.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC158991 Genomic DNA. No translation available.
AF008595 mRNA. Translation: AAB67069.1.
BC115490 mRNA. Translation: AAI15491.1.
BC115491 mRNA. Translation: AAI15492.1.
GU269233 mRNA. Translation: ADB46068.1.
KM014043 Genomic DNA. Translation: AIQ80460.1.
CH466593 Genomic DNA. Translation: EDL23944.1.
RefSeqiNP_065588.1. NM_020563.3.
UniGeneiMm.6205.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000079468.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000080635; ENSMUSP00000079468; ENSMUSG00000062556.
GeneIDi57426.
KEGGimmu:57426.
UCSCiuc009gii.2. mouse.

Organism-specific databases

CTDi57426.
MGIiMGI:1930867. Scgb1b2.

Phylogenomic databases

eggNOGiENOG410JG59. Eukaryota.
ENOG4111DIV. LUCA.
GeneTreeiENSGT00390000009774.
HOGENOMiHOG000232163.
HOVERGENiHBG051604.
OMAiKEHAAAF.
OrthoDBiEOG7Q2N84.
TreeFamiTF339838.

Miscellaneous databases

NextBioi313786.
SOURCEiSearch...

Family and domain databases

InterProiIPR006178. Allergen_Fel_d_I_chain1.
IPR016126. Secretoglobin.
[Graphical view]
PfamiPF01099. Uteroglobin. 1 hit.
[Graphical view]
PRINTSiPR00827. FELALLERGEN.
SMARTiSM00096. UTG. 1 hit.
[Graphical view]
SUPFAMiSSF48201. SSF48201. 1 hit.
PROSITEiPS51311. SCGB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Lima P.L., Remington S.G., Georges S.A., Nelson J.D.
    Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Lacrimal glandImported.
  2. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. "Comparative evolutionary genomics of androgen-binding protein genes."
    Emes R.D., Riley M.C., Laukaitis C.M., Goodstadt L., Karn R.C., Ponting C.P.
    Genome Res. 14:1516-1529(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C3H/HeJImported.
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  5. "Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus."
    Laukaitis C.M., Dlouhy S.R., Emes R.D., Ponting C.P., Karn R.C.
    BMC Evol. Biol. 5:40-40(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C3H/HeJImported.
  6. "Secretoglobins: sexually dimorphic expression of androgen-binding protein mRNA in mouse lacrimal glands."
    Remington S.G., Nelson J.D.
    Invest. Ophthalmol. Vis. Sci. 46:31-38(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Lacrimal glandImported.
  7. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  8. "Rapid bursts of androgen-binding protein (Abp) gene duplication occurred independently in diverse mammals."
    Laukaitis C.M., Heger A., Blakley T.D., Munclinger P., Ponting C.P., Karn R.C.
    BMC Evol. Biol. 8:46-46(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C3H/HeJImported.
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  10. Laukaitis C.M., Heger A., Blakley T.D., Munclinger P., Ponting C.P., Karn R.C.
    Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C3H/HeJImported.
  11. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  12. "Selection shaped the evolution of mouse androgen-binding protein (ABP) function and promoted the duplication of Abp genes."
    Karn R.C., Laukaitis C.M.
    Biochem. Soc. Trans. 42:851-860(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.
  13. "Did androgen-binding protein paralogs undergo neo- and/or Subfunctionalization as the Abp gene region expanded in the mouse genome?"
    Karn R.C., Chung A.G., Laukaitis C.M.
    PLoS ONE 9:E115454-E115454(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6Imported.

Entry informationi

Entry nameiO35176_MOUSE
AccessioniPrimary (citable) accession number: O35176
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: May 11, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.