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Protein

Heat shock 70 kDa protein 13

Gene

Hspa13

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Has peptide-independent ATPase activity.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Heat shock 70 kDa protein 13
Alternative name(s):
Microsomal stress-70 protein ATPase core
Stress-70 protein chaperone microsome-associated 60 kDa protein
Gene namesi
Name:Hspa13
Synonyms:Stch
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 11

Organism-specific databases

RGDi3775. Hspa13.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Microsome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 471449Heat shock 70 kDa protein 13PRO_0000013561Add
BLAST

Proteomic databases

PaxDbiO35162.

PTM databases

UniCarbKBiO35162.

Expressioni

Gene expression databases

BgeeiENSRNOG00000032834.
ExpressionAtlasiO35162. differential.
GenevisibleiO35162. RN.

Interactioni

Subunit structurei

Binds UBQLN2.By similarity

Protein-protein interaction databases

MINTiMINT-4569482.
STRINGi10116.ENSRNOP00000049545.

Structurei

3D structure databases

ProteinModelPortaliO35162.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
GeneTreeiENSGT00840000129922.
HOGENOMiHOG000228135.
HOVERGENiHBG098979.
InParanoidiO35162.
KOiK09491.
OMAiQIYQTYG.
OrthoDBiEOG091G06OD.
PhylomeDBiO35162.
TreeFamiTF105047.

Family and domain databases

InterProiIPR018181. Heat_shock_70_CS.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 2 hits.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O35162-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGEMTILGS AVLTLLLAGY LAQQYLPLPT PKVIGIDLGT TYCSVGVFFP
60 70 80 90 100
GTGKVKVIPD ENGHISIPSM VSFTDGDVYV GYESLELADS NPQNTIYDAK
110 120 130 140 150
RFIGKIFTPE ELEAEIGRYP FKVLHKNGMA EFSVTSNETI IVSPEYVGSR
160 170 180 190 200
LLLKLKEMAE KYLGMPVANA VISVPAEFDL QQRNSTIQAA NLAGLKILRV
210 220 230 240 250
INEPTAAAMA YGLHKVDVFY VLVIDLGGGT LDVSLLNKQG GMFLTRAMSG
260 270 280 290 300
NNKLGGQDFN QRLLQYLYKE IYQTYGFLPS RKEEIHRLRQ AVEMVKLNLT
310 320 330 340 350
LHQSAQVSVL LTVEENDSQK PQNADSKLPE DQLTPGDGHH VNRVFRPGLS
360 370 380 390 400
DSTSGKSQVL FETEVSRKLF NTLNEDLFQK ILVPIQQVLK EGLLDKTEID
410 420 430 440 450
EVVLVGGSTR IPRIRQVIQE FFGKDPNTSV DPDLAVVTGV AIQAGIDGGS
460 470
WPLQVSALEI PNKHLQKTNF N
Length:471
Mass (Da):51,795
Last modified:June 7, 2005 - v2
Checksum:i24134E56E195FCDC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti355 – 3551G → A (PubMed:8131751).Curated
Sequence conflicti355 – 3551G → A (PubMed:9358068).Curated
Sequence conflicti450 – 4501S → C (PubMed:8131751).Curated
Sequence conflicti450 – 4501S → C (PubMed:9358068).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF006617 mRNA. Translation: AAB88258.1.
BC070954 mRNA. Translation: AAH70954.1.
RefSeqiNP_062144.2. NM_019271.2.
UniGeneiRn.11050.

Genome annotation databases

EnsembliENSRNOT00000081096; ENSRNOP00000070174; ENSRNOG00000060979.
GeneIDi29734.
KEGGirno:29734.
UCSCiRGD:3775. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF006617 mRNA. Translation: AAB88258.1.
BC070954 mRNA. Translation: AAH70954.1.
RefSeqiNP_062144.2. NM_019271.2.
UniGeneiRn.11050.

3D structure databases

ProteinModelPortaliO35162.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-4569482.
STRINGi10116.ENSRNOP00000049545.

PTM databases

UniCarbKBiO35162.

Proteomic databases

PaxDbiO35162.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000081096; ENSRNOP00000070174; ENSRNOG00000060979.
GeneIDi29734.
KEGGirno:29734.
UCSCiRGD:3775. rat.

Organism-specific databases

CTDi6782.
RGDi3775. Hspa13.

Phylogenomic databases

eggNOGiKOG0101. Eukaryota.
COG0443. LUCA.
GeneTreeiENSGT00840000129922.
HOGENOMiHOG000228135.
HOVERGENiHBG098979.
InParanoidiO35162.
KOiK09491.
OMAiQIYQTYG.
OrthoDBiEOG091G06OD.
PhylomeDBiO35162.
TreeFamiTF105047.

Miscellaneous databases

PROiO35162.

Gene expression databases

BgeeiENSRNOG00000032834.
ExpressionAtlasiO35162. differential.
GenevisibleiO35162. RN.

Family and domain databases

InterProiIPR018181. Heat_shock_70_CS.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 2 hits.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiHSP13_RAT
AccessioniPrimary (citable) accession number: O35162
Secondary accession number(s): Q6IRE1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: September 7, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.