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Protein
Submitted name:

Sodium-dependent dicarboxylate transporter

Gene

Slc13a2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-433137. Sodium-coupled sulphate, di- and tri-carboxylate transporters.

Protein family/group databases

TCDBi2.A.47.1.3. the divalent anion:na(+) symporter (dass) family.

Names & Taxonomyi

Protein namesi
Submitted name:
Sodium-dependent dicarboxylate transporterImported
Submitted name:
Sodium-dicarboxylate cotransporter SDCT1Imported
Submitted name:
Solute carrier family 13 (Sodium-dependent dicarboxylate transporter), member 2, isoform CRA_aImported
Submitted name:
Solute carrier family 13 member 2Imported
Gene namesi
Name:Slc13a2Imported
Synonyms:rNaDC-1Imported
ORF Names:rCG_32564Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi61920. Slc13a2.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 31HelicalSequence analysisAdd BLAST20
Transmembranei43 – 67HelicalSequence analysisAdd BLAST25
Transmembranei87 – 105HelicalSequence analysisAdd BLAST19
Transmembranei117 – 139HelicalSequence analysisAdd BLAST23
Transmembranei258 – 280HelicalSequence analysisAdd BLAST23
Transmembranei322 – 340HelicalSequence analysisAdd BLAST19
Transmembranei360 – 379HelicalSequence analysisAdd BLAST20
Transmembranei412 – 429HelicalSequence analysisAdd BLAST18
Transmembranei449 – 465HelicalSequence analysisAdd BLAST17
Transmembranei477 – 496HelicalSequence analysisAdd BLAST20
Transmembranei502 – 524HelicalSequence analysisAdd BLAST23
Transmembranei536 – 555HelicalSequence analysisAdd BLAST20

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000010337.
ExpressionAtlasiO35055. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000038185.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1281. Eukaryota.
COG0471. LUCA.
GeneTreeiENSGT00550000074480.
HOVERGENiHBG055339.
KOiK14445.
OMAiQRFPRGG.
OrthoDBiEOG091G092X.
TreeFamiTF312913.

Family and domain databases

InterProiIPR001898. Na/sul_symport.
IPR031312. Na/sul_symport_CS.
[Graphical view]
PfamiPF00939. Na_sulph_symp. 1 hit.
[Graphical view]
PROSITEiPS01271. NA_SULFATE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O35055-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATCWPALWA YRFYLIVLCL PIFLLPLPLI VQTKEAYCAY SIILMALLWC
60 70 80 90 100
TEALPLAVTA LFPIVLFPLM GIMDASEVCI EYFKDTNILF VGGLMVAIAV
110 120 130 140 150
EHWNLHKRIA LQVLLIIGVR PALLLLGFML VTAFLSMWIS NTATTAMMVP
160 170 180 190 200
IGHAVLEQLQ GSKKDVEGGN NNPTFELQEE CPQKEVTKLD NGQPVSAPSE
210 220 230 240 250
PRTQKTQEHH RFSQGLSLCI CYSASIGGIA TLTGTTPNLV LQGQVNSLFP
260 270 280 290 300
QNGNVVNFAS WFGFAFPTMI ILLLLAWLWL QVLFLGVNFR KNFGFGEGEE
310 320 330 340 350
ERKQAAFQVI KTQYRLLGPM SFAEKTVTVL FVLLVVLWFT REPGFFPGWG
360 370 380 390 400
DTVFANEKGQ SMASDGTVAI FISLVMFIIP SKIPGLMQDP KKPGKLKAPP
410 420 430 440 450
AILTWKTVND KMPWNIVILL GGGFALAKGS EQSGLSEWLG DKLTPLQHIP
460 470 480 490 500
PSATAVILCL LIAIFTECTS NVATTTLFLP ILASMAQAIC LHPLYVMLPC
510 520 530 540 550
TLAASLAFML PVATPPNAIV FSFGGLKVSD MARAGFLLNI IGVLAITLSI
560 570 580
NSWSIPIFKL DTFPSWAHSN TSQCLLNPSN STVPGGL
Length:587
Mass (Da):64,143
Last modified:August 1, 1998 - v2
Checksum:i844E47C77F8F9CDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07030074 Genomic DNA. No translation available.
AF058714 mRNA. Translation: AAC31165.1.
AB001321 mRNA. Translation: BAA28609.1.
CH473948 Genomic DNA. Translation: EDM05353.1.
RefSeqiNP_113934.1. NM_031746.1.
UniGeneiRn.10821.

Genome annotation databases

EnsembliENSRNOT00000038690; ENSRNOP00000038185; ENSRNOG00000010337.
GeneIDi65202.
KEGGirno:65202.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07030074 Genomic DNA. No translation available.
AF058714 mRNA. Translation: AAC31165.1.
AB001321 mRNA. Translation: BAA28609.1.
CH473948 Genomic DNA. Translation: EDM05353.1.
RefSeqiNP_113934.1. NM_031746.1.
UniGeneiRn.10821.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000038185.

Protein family/group databases

TCDBi2.A.47.1.3. the divalent anion:na(+) symporter (dass) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000038690; ENSRNOP00000038185; ENSRNOG00000010337.
GeneIDi65202.
KEGGirno:65202.

Organism-specific databases

CTDi9058.
RGDi61920. Slc13a2.

Phylogenomic databases

eggNOGiKOG1281. Eukaryota.
COG0471. LUCA.
GeneTreeiENSGT00550000074480.
HOVERGENiHBG055339.
KOiK14445.
OMAiQRFPRGG.
OrthoDBiEOG091G092X.
TreeFamiTF312913.

Enzyme and pathway databases

ReactomeiR-RNO-433137. Sodium-coupled sulphate, di- and tri-carboxylate transporters.

Gene expression databases

BgeeiENSRNOG00000010337.
ExpressionAtlasiO35055. baseline and differential.

Family and domain databases

InterProiIPR001898. Na/sul_symport.
IPR031312. Na/sul_symport_CS.
[Graphical view]
PfamiPF00939. Na_sulph_symp. 1 hit.
[Graphical view]
PROSITEiPS01271. NA_SULFATE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO35055_RAT
AccessioniPrimary (citable) accession number: O35055
Entry historyi
Integrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 110 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.