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Protein

Sensor protein BceS

Gene

bceS

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Member of the two-component regulatory system BceS/BceR involved in the regulation of bacitracin resistance. Activates BceR in response to extracellular bacitracin.3 Publications

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processTwo-component regulatory system
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU30390-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Sensor protein BceS (EC:2.7.13.3)
Gene namesi
Name:bceS
Synonyms:barB, ytsB
Ordered Locus Names:BSU30390
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 12CytoplasmicSequence analysisAdd BLAST12
Transmembranei13 – 33HelicalSequence analysisAdd BLAST21
Topological domaini34ExtracellularSequence analysis1
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Topological domaini56 – 334CytoplasmicSequence analysisAdd BLAST279

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000747091 – 334Sensor protein BceSAdd BLAST334

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei124Phosphohistidine; by autocatalysisPROSITE-ProRule annotation1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO35044
PRIDEiO35044

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100016546

Structurei

3D structure databases

ProteinModelPortaliO35044
SMRiO35044
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini121 – 326Histidine kinasePROSITE-ProRule annotationAdd BLAST206

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EWM Bacteria
COG0642 LUCA
HOGENOMiHOG000032012
InParanoidiO35044
KOiK11629
OMAiYEWLRIH
PhylomeDBiO35044

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR005467 His_kinase_dom
IPR004358 Sig_transdc_His_kin-like_C
PfamiView protein in Pfam
PF02518 HATPase_c, 1 hit
PRINTSiPR00344 BCTRLSENSOR
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF55874 SSF55874, 1 hit
PROSITEiView protein in PROSITE
PS50109 HIS_KIN, 1 hit

Sequencei

Sequence statusi: Complete.

O35044-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKAFLIERR SWIAAFLFQQ ALMLFIAFVD PSISFGNVLY MVYLCILFFI
60 70 80 90 100
IFLWFRYRKE TAFYKSLKTW ENNLDVTAIN EPETPFEAMV ERSIAGQTEH
110 120 130 140 150
LKQTAARHRL ALENEKDELM AWIHEVKTPL TAMHLIIDRM EEKALKSQLS
160 170 180 190 200
YEWLRIHLLL DQQLHQKRIS FIENDLSVEF IQLQPLIFKE IKDLQSWCIQ
210 220 230 240 250
KGIGFDIQLE AKEVLSDAKW LAFIIRQLLT NAVKYSEASE IEIKSFQKGE
260 270 280 290 300
QTQLQVKDCG RGIDPKDVPR IFDKGFTSTT DHHDQASTGM GLYLAKKAAA
310 320 330
PLLIHIDVES EFGAGTVFTL TFPIRNQFEH VISV
Length:334
Mass (Da):38,765
Last modified:January 1, 1998 - v1
Checksum:i2BED582B96FCF482
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA Translation: AAC00254.1
AL009126 Genomic DNA Translation: CAB15017.1
PIRiH70000
RefSeqiNP_390917.1, NC_000964.3
WP_004398652.1, NZ_JNCM01000036.1

Genome annotation databases

EnsemblBacteriaiCAB15017; CAB15017; BSU30390
GeneIDi936816
KEGGibsu:BSU30390
PATRICifig|224308.179.peg.3296

Entry informationi

Entry nameiBCES_BACSU
AccessioniPrimary (citable) accession number: O35044
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 2, 2004
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

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