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Protein

Putative monooxygenase MoxC

Gene

moxC

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in methionine degradation. May play a role in a sulfur salvage pathway.1 Publication

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei58FMN; via amide nitrogen and carbonyl oxygen1 Publication1
Binding sitei95FMN1 Publication1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi145 – 149FMN binding1 Publication5
Nucleotide bindingi217 – 220FMN binding1 Publication4

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN

Enzyme and pathway databases

BioCyciBSUB:BSU29310-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative monooxygenase MoxC (EC:1.14.-.-)
Gene namesi
Name:moxC
Synonyms:ytnJ
Ordered Locus Names:BSU29310
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Pathology & Biotechi

Disruption phenotypei

Reduced growth with methionine or methionine sulfoxide as unique source of sulfur.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003606221 – 442Putative monooxygenase MoxCAdd BLAST442

Proteomic databases

PaxDbiO34974.

Expressioni

Inductioni

Induced when methionine is the sulfur source, but not by sulfate.1 Publication

Interactioni

Subunit structurei

Homodimer.1 Publication

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100016001.

Structurei

Secondary structure

1442
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 12Combined sources5
Beta strandi18 – 21Combined sources4
Helixi22 – 24Combined sources3
Helixi32 – 34Combined sources3
Helixi36 – 48Combined sources13
Beta strandi52 – 56Combined sources5
Helixi68 – 71Combined sources4
Helixi76 – 84Combined sources9
Beta strandi91 – 97Combined sources7
Turni98 – 100Combined sources3
Helixi103 – 116Combined sources14
Beta strandi121 – 127Combined sources7
Helixi131 – 134Combined sources4
Turni135 – 138Combined sources4
Helixi145 – 163Combined sources19
Turni175 – 178Combined sources4
Helixi183 – 185Combined sources3
Beta strandi213 – 216Combined sources4
Helixi221 – 230Combined sources10
Beta strandi232 – 236Combined sources5
Helixi241 – 257Combined sources17
Helixi262 – 264Combined sources3
Beta strandi265 – 271Combined sources7
Helixi279 – 290Combined sources12
Helixi295 – 298Combined sources4
Helixi349 – 357Combined sources9
Beta strandi362 – 365Combined sources4
Helixi367 – 379Combined sources13
Beta strandi384 – 388Combined sources5
Helixi395 – 409Combined sources15
Helixi422 – 426Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TVLX-ray2.10A2-442[»]
1YW1X-ray2.81A1-442[»]
ProteinModelPortaliO34974.
SMRiO34974.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO34974.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2141. LUCA.
HOGENOMiHOG000190807.
InParanoidiO34974.
OMAiKAHHIRR.
PhylomeDBiO34974.

Family and domain databases

Gene3Di3.20.20.30. 2 hits.
InterProiIPR011251. Luciferase-like_dom.
IPR016215. NTA_MOA.
[Graphical view]
PfamiPF00296. Bac_luciferase. 1 hit.
[Graphical view]
PIRSFiPIRSF000337. NTA_MOA. 1 hit.
SUPFAMiSSF51679. SSF51679. 1 hit.
TIGRFAMsiTIGR03860. FMN_nitrolo. 1 hit.

Sequencei

Sequence statusi: Complete.

O34974-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRADFIQFG AMIHGVGGTT DGWRHPDVDP SASTNIEFYM KKAQTAEKGL
60 70 80 90 100
FSFIFIADGL FISEKSIPHF LNRFEPITIL SALASVTKNI GLVGTFSTSF
110 120 130 140 150
TEPFTISRQL MSLDHISGGR AGWNLVTSPQ EGAARNHSKS NLPEHTERYE
160 170 180 190 200
IAQEHLDVVR GLWNSWEHDA FIHNKKTGQF FDQAKLHRLN HKGKYFQVEG
210 220 230 240 250
PLNIGRSKQG EPVVFQAGSS ETGRQFAAKN ADAIFTHSNS LEETKAFYAD
260 270 280 290 300
VKSRAADEGR DPSSVRIFPG ISPIVADTEE EAEKKYREFA ELIPIENAVT
310 320 330 340 350
YLARFFDDYD LSVYPLDEPF PDIGDVGKNA FQSTTDRIKR EAKARNLTLR
360 370 380 390 400
EVAQEMAFPR TLFIGTPERV ASLIETWFNA EAADGFIVGS DIPGTLDAFV
410 420 430 440
EKVIPILQER GLYRQDYRGG TLRENLGLGI PQHQSVLHSS HH
Length:442
Mass (Da):49,411
Last modified:January 1, 1998 - v1
Checksum:i8C9D72FEB983FBF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00332.1.
AL009126 Genomic DNA. Translation: CAB14891.1.
PIRiE69997.
RefSeqiNP_390809.1. NC_000964.3.
WP_004398733.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14891; CAB14891; BSU29310.
GeneIDi937365.
KEGGibsu:BSU29310.
PATRICi18977762. VBIBacSub10457_3069.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00332.1.
AL009126 Genomic DNA. Translation: CAB14891.1.
PIRiE69997.
RefSeqiNP_390809.1. NC_000964.3.
WP_004398733.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TVLX-ray2.10A2-442[»]
1YW1X-ray2.81A1-442[»]
ProteinModelPortaliO34974.
SMRiO34974.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100016001.

Proteomic databases

PaxDbiO34974.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14891; CAB14891; BSU29310.
GeneIDi937365.
KEGGibsu:BSU29310.
PATRICi18977762. VBIBacSub10457_3069.

Phylogenomic databases

eggNOGiCOG2141. LUCA.
HOGENOMiHOG000190807.
InParanoidiO34974.
OMAiKAHHIRR.
PhylomeDBiO34974.

Enzyme and pathway databases

BioCyciBSUB:BSU29310-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO34974.

Family and domain databases

Gene3Di3.20.20.30. 2 hits.
InterProiIPR011251. Luciferase-like_dom.
IPR016215. NTA_MOA.
[Graphical view]
PfamiPF00296. Bac_luciferase. 1 hit.
[Graphical view]
PIRSFiPIRSF000337. NTA_MOA. 1 hit.
SUPFAMiSSF51679. SSF51679. 1 hit.
TIGRFAMsiTIGR03860. FMN_nitrolo. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMOXC_BACSU
AccessioniPrimary (citable) accession number: O34974
Secondary accession number(s): Q795U8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.