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Protein

Putative monooxygenase MoxC

Gene

moxC

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in methionine degradation. May play a role in a sulfur salvage pathway.1 Publication

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei58 – 581FMN; via amide nitrogen and carbonyl oxygen1 Publication
Binding sitei95 – 951FMN1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi145 – 1495FMN binding1 Publication
Nucleotide bindingi217 – 2204FMN binding1 Publication

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Monooxygenase, Oxidoreductase

Keywords - Ligandi

Flavoprotein, FMN

Enzyme and pathway databases

BioCyciBSUB:BSU29310-MONOMER.
RETL1328306-WGS:GSTH-6599-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative monooxygenase MoxC (EC:1.14.-.-)
Gene namesi
Name:moxC
Synonyms:ytnJ
Ordered Locus Names:BSU29310
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Pathology & Biotechi

Disruption phenotypei

Reduced growth with methionine or methionine sulfoxide as unique source of sulfur.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 442442Putative monooxygenase MoxCPRO_0000360622Add
BLAST

Proteomic databases

PaxDbiO34974.

Expressioni

Inductioni

Induced when methionine is the sulfur source, but not by sulfate.1 Publication

Interactioni

Subunit structurei

Homodimer.1 Publication

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100016001.

Structurei

Secondary structure

1
442
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi8 – 125Combined sources
Beta strandi18 – 214Combined sources
Helixi22 – 243Combined sources
Helixi32 – 343Combined sources
Helixi36 – 4813Combined sources
Beta strandi52 – 565Combined sources
Helixi68 – 714Combined sources
Helixi76 – 849Combined sources
Beta strandi91 – 977Combined sources
Turni98 – 1003Combined sources
Helixi103 – 11614Combined sources
Beta strandi121 – 1277Combined sources
Helixi131 – 1344Combined sources
Turni135 – 1384Combined sources
Helixi145 – 16319Combined sources
Turni175 – 1784Combined sources
Helixi183 – 1853Combined sources
Beta strandi213 – 2164Combined sources
Helixi221 – 23010Combined sources
Beta strandi232 – 2365Combined sources
Helixi241 – 25717Combined sources
Helixi262 – 2643Combined sources
Beta strandi265 – 2717Combined sources
Helixi279 – 29012Combined sources
Helixi295 – 2984Combined sources
Helixi349 – 3579Combined sources
Beta strandi362 – 3654Combined sources
Helixi367 – 37913Combined sources
Beta strandi384 – 3885Combined sources
Helixi395 – 40915Combined sources
Helixi422 – 4265Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TVLX-ray2.10A2-442[»]
1YW1X-ray2.81A1-442[»]
ProteinModelPortaliO34974.
SMRiO34974. Positions 3-431.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO34974.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2141. LUCA.
HOGENOMiHOG000190807.
InParanoidiO34974.
OMAiKAHHIRR.
PhylomeDBiO34974.

Family and domain databases

Gene3Di3.20.20.30. 2 hits.
InterProiIPR011251. Luciferase-like_dom.
IPR016215. NTA_MOA.
[Graphical view]
PfamiPF00296. Bac_luciferase. 1 hit.
[Graphical view]
PIRSFiPIRSF000337. NTA_MOA. 1 hit.
SUPFAMiSSF51679. SSF51679. 1 hit.
TIGRFAMsiTIGR03860. FMN_nitrolo. 1 hit.

Sequencei

Sequence statusi: Complete.

O34974-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRADFIQFG AMIHGVGGTT DGWRHPDVDP SASTNIEFYM KKAQTAEKGL
60 70 80 90 100
FSFIFIADGL FISEKSIPHF LNRFEPITIL SALASVTKNI GLVGTFSTSF
110 120 130 140 150
TEPFTISRQL MSLDHISGGR AGWNLVTSPQ EGAARNHSKS NLPEHTERYE
160 170 180 190 200
IAQEHLDVVR GLWNSWEHDA FIHNKKTGQF FDQAKLHRLN HKGKYFQVEG
210 220 230 240 250
PLNIGRSKQG EPVVFQAGSS ETGRQFAAKN ADAIFTHSNS LEETKAFYAD
260 270 280 290 300
VKSRAADEGR DPSSVRIFPG ISPIVADTEE EAEKKYREFA ELIPIENAVT
310 320 330 340 350
YLARFFDDYD LSVYPLDEPF PDIGDVGKNA FQSTTDRIKR EAKARNLTLR
360 370 380 390 400
EVAQEMAFPR TLFIGTPERV ASLIETWFNA EAADGFIVGS DIPGTLDAFV
410 420 430 440
EKVIPILQER GLYRQDYRGG TLRENLGLGI PQHQSVLHSS HH
Length:442
Mass (Da):49,411
Last modified:January 1, 1998 - v1
Checksum:i8C9D72FEB983FBF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00332.1.
AL009126 Genomic DNA. Translation: CAB14891.1.
PIRiE69997.
RefSeqiNP_390809.1. NC_000964.3.
WP_004398733.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14891; CAB14891; BSU29310.
GeneIDi937365.
KEGGibsu:BSU29310.
PATRICi18977762. VBIBacSub10457_3069.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00332.1.
AL009126 Genomic DNA. Translation: CAB14891.1.
PIRiE69997.
RefSeqiNP_390809.1. NC_000964.3.
WP_004398733.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TVLX-ray2.10A2-442[»]
1YW1X-ray2.81A1-442[»]
ProteinModelPortaliO34974.
SMRiO34974. Positions 3-431.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100016001.

Proteomic databases

PaxDbiO34974.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14891; CAB14891; BSU29310.
GeneIDi937365.
KEGGibsu:BSU29310.
PATRICi18977762. VBIBacSub10457_3069.

Phylogenomic databases

eggNOGiCOG2141. LUCA.
HOGENOMiHOG000190807.
InParanoidiO34974.
OMAiKAHHIRR.
PhylomeDBiO34974.

Enzyme and pathway databases

BioCyciBSUB:BSU29310-MONOMER.
RETL1328306-WGS:GSTH-6599-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO34974.

Family and domain databases

Gene3Di3.20.20.30. 2 hits.
InterProiIPR011251. Luciferase-like_dom.
IPR016215. NTA_MOA.
[Graphical view]
PfamiPF00296. Bac_luciferase. 1 hit.
[Graphical view]
PIRSFiPIRSF000337. NTA_MOA. 1 hit.
SUPFAMiSSF51679. SSF51679. 1 hit.
TIGRFAMsiTIGR03860. FMN_nitrolo. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMOXC_BACSU
AccessioniPrimary (citable) accession number: O34974
Secondary accession number(s): Q795U8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.