Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O34925

- DEOD_BACSU

UniProt

O34925 - DEOD_BACSU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Purine nucleoside phosphorylase DeoD-type

Gene

deoD

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Cleavage of adenosine and its derivatives.

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.

GO - Molecular functioni

  1. purine-nucleoside phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. purine nucleoside metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciBSUB:BSU19630-MONOMER.
SABIO-RKO34925.

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylase DeoD-type (EC:2.4.2.1)
Short name:
PNP
Alternative name(s):
Purine nucleoside phosphorylase II
Short name:
PU-NPase II
Gene namesi
Name:deoD
Synonyms:punB
Ordered Locus Names:BSU19630
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
ProteomesiUP000001570: Chromosome

Organism-specific databases

GenoListiBSU19630. [Micado]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 233233Purine nucleoside phosphorylase DeoD-typePRO_0000063121Add
BLAST

Proteomic databases

PaxDbiO34925.

Interactioni

Subunit structurei

Homohexamer.By similarity

Protein-protein interaction databases

IntActiO34925. 1 interaction.
MINTiMINT-8366691.
STRINGi224308.BSU19630.

Structurei

Secondary structure

1
233
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi9 – 113Combined sources
Beta strandi14 – 185Combined sources
Helixi22 – 3211Combined sources
Beta strandi34 – 407Combined sources
Helixi42 – 443Combined sources
Beta strandi47 – 526Combined sources
Beta strandi55 – 606Combined sources
Helixi66 – 8015Combined sources
Beta strandi84 – 9310Combined sources
Beta strandi95 – 984Combined sources
Beta strandi103 – 11210Combined sources
Helixi115 – 1206Combined sources
Helixi131 – 14414Combined sources
Beta strandi148 – 1558Combined sources
Helixi166 – 1716Combined sources
Beta strandi176 – 1805Combined sources
Helixi181 – 19010Combined sources
Beta strandi194 – 20411Combined sources
Turni205 – 2073Combined sources
Helixi213 – 22715Combined sources
Turni228 – 2303Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4D8VX-ray2.35A/B1-233[»]
4D8XX-ray2.65A1-233[»]
4D8YX-ray1.61A/B/C/D/E/F1-233[»]
4D98X-ray1.70A/B1-233[»]
4D9HX-ray1.91A/B1-233[»]
4DA0X-ray2.95A1-233[»]
4DA6X-ray1.70A1-233[»]
4DA7X-ray2.05A1-233[»]
4DA8X-ray2.60A1-233[»]
4DABX-ray1.85A1-233[»]
4DAEX-ray2.35A1-233[»]
4DANX-ray2.56A/B1-233[»]
4DAOX-ray2.22A/B1-233[»]
4DARX-ray3.15A1-233[»]
ProteinModelPortaliO34925.
SMRiO34925. Positions 1-228.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.Curated

Phylogenomic databases

eggNOGiCOG0813.
HOGENOMiHOG000274896.
InParanoidiO34925.
KOiK03784.
OMAiECYNEVR.
OrthoDBiEOG6BKJC5.
PhylomeDBiO34925.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O34925-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVHIGAEKG QIADTVLLPG DPLRAKFIAE TYLENVECYN EVRGMYGFTG
60 70 80 90 100
TYKGKKISVQ GTGMGVPSIS IYVNELIQSY DVQNLIRVGS CGAIRKDVKV
110 120 130 140 150
RDVILAMTSS TDSQMNRVAF GSVDFAPCAD FELLKNAYDA AKDKGVPVTV
160 170 180 190 200
GSVFTADQFY NDDSQIEKLA KYGVLGVEME TTALYTLAAK HGRKALSILT
210 220 230
VSDHVLTGEE TTAEERQTTF HDMIEVALHS VSQ
Length:233
Mass (Da):25,378
Last modified:January 1, 1998 - v1
Checksum:i645FD21146E8F613
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF015775 Genomic DNA. Translation: AAB72065.1.
AF006665 Genomic DNA. Translation: AAB81164.1.
AL009126 Genomic DNA. Translation: CAB13854.1.
PIRiD69614.
RefSeqiNP_389844.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB13854; CAB13854; BSU19630.
GeneIDi940038.
KEGGibsu:BSU19630.
PATRICi18975779. VBIBacSub10457_2080.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF015775 Genomic DNA. Translation: AAB72065.1 .
AF006665 Genomic DNA. Translation: AAB81164.1 .
AL009126 Genomic DNA. Translation: CAB13854.1 .
PIRi D69614.
RefSeqi NP_389844.1. NC_000964.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4D8V X-ray 2.35 A/B 1-233 [» ]
4D8X X-ray 2.65 A 1-233 [» ]
4D8Y X-ray 1.61 A/B/C/D/E/F 1-233 [» ]
4D98 X-ray 1.70 A/B 1-233 [» ]
4D9H X-ray 1.91 A/B 1-233 [» ]
4DA0 X-ray 2.95 A 1-233 [» ]
4DA6 X-ray 1.70 A 1-233 [» ]
4DA7 X-ray 2.05 A 1-233 [» ]
4DA8 X-ray 2.60 A 1-233 [» ]
4DAB X-ray 1.85 A 1-233 [» ]
4DAE X-ray 2.35 A 1-233 [» ]
4DAN X-ray 2.56 A/B 1-233 [» ]
4DAO X-ray 2.22 A/B 1-233 [» ]
4DAR X-ray 3.15 A 1-233 [» ]
ProteinModelPortali O34925.
SMRi O34925. Positions 1-228.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi O34925. 1 interaction.
MINTi MINT-8366691.
STRINGi 224308.BSU19630.

Proteomic databases

PaxDbi O34925.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB13854 ; CAB13854 ; BSU19630 .
GeneIDi 940038.
KEGGi bsu:BSU19630.
PATRICi 18975779. VBIBacSub10457_2080.

Organism-specific databases

GenoListi BSU19630. [Micado ]

Phylogenomic databases

eggNOGi COG0813.
HOGENOMi HOG000274896.
InParanoidi O34925.
KOi K03784.
OMAi ECYNEVR.
OrthoDBi EOG6BKJC5.
PhylomeDBi O34925.

Enzyme and pathway databases

BioCyci BSUB:BSU19630-MONOMER.
SABIO-RK O34925.

Family and domain databases

Gene3Di 3.40.50.1580. 1 hit.
HAMAPi MF_01627. Pur_nucleosid_phosp.
InterProi IPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view ]
PANTHERi PTHR21234. PTHR21234. 1 hit.
Pfami PF01048. PNP_UDP_1. 1 hit.
[Graphical view ]
SUPFAMi SSF53167. SSF53167. 1 hit.
TIGRFAMsi TIGR00107. deoD. 1 hit.
PROSITEi PS01232. PNP_UDP_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence analysis of the Bacillus subtilis 168 chromosome region between the sspC and odhA loci (184 degrees-180 degrees)."
    Ghim S.-Y., Choi S.-K., Shin B.-S., Jeong Y.-M., Sorokin A., Ehrlich S.D., Park S.-H.
    DNA Res. 5:195-201(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.

Entry informationi

Entry nameiDEOD_BACSU
AccessioniPrimary (citable) accession number: O34925
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: November 26, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3