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Protein

Glycine betaine/carnitine/choline transport system permease protein OpuCB

Gene

opuCB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in a high affinity multicomponent binding-protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane.2 Publications

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU33820-MONOMER

Protein family/group databases

TCDBi3.A.1.12.4 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine betaine/carnitine/choline transport system permease protein OpuCB
Gene namesi
Name:opuCB
Synonyms:yvbD
Ordered Locus Names:BSU33820
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 43HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei52 – 74HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei84 – 101HelicalPROSITE-ProRule annotationAdd BLAST18
Transmembranei128 – 148HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei150 – 170HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei180 – 200HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000601561 – 217Glycine betaine/carnitine/choline transport system permease protein OpuCBAdd BLAST217

Proteomic databases

PaxDbiO34878
PRIDEiO34878

Expressioni

Inductioni

Repressed by OpcR.1 Publication

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (OpuCA), two transmembrane proteins (OpuCB and OpuCD) and a solute-binding protein (OpuCC).1 Publication

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100018346

Structurei

3D structure databases

ProteinModelPortaliO34878
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 198ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST180

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105E90 Bacteria
COG1174 LUCA
HOGENOMiHOG000012907
InParanoidiO34878
KOiK05846
OMAiVVTNIAM
PhylomeDBiO34878

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 1 hit
InterProiView protein in InterPro
IPR000515 MetI-like
IPR035906 MetI-like_sf
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

O34878-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQMMTFLQT NGGELLYKTG EHLYISLIAV VLGIIVAVPL GVALTRMKKG
60 70 80 90 100
AGAVIGFVNI VQTLPSLAIL AFFIPLLGVG KVPAIVALFF YSVLPILRNT
110 120 130 140 150
YTGIKGVNKN LLESGKGIGM TGWEQIRLVE IPLAIPIIMA GIRTSTIYLI
160 170 180 190 200
GWATLASFIG GGGLGDYIFI GLNLYQPEYI IGGAVPVTIL AIIIDYVLAV
210
TERKVTPKGL QGMKEVS
Length:217
Mass (Da):23,149
Last modified:January 1, 1998 - v1
Checksum:i5A056B2167770E95
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF009352 Genomic DNA Translation: AAB63769.1
AL009126 Genomic DNA Translation: CAB15387.1
PIRiD69670
RefSeqiNP_391262.1, NC_000964.3
WP_003228349.1, NZ_JNCM01000033.1

Genome annotation databases

EnsemblBacteriaiCAB15387; CAB15387; BSU33820
GeneIDi937105
KEGGibsu:BSU33820
PATRICifig|224308.179.peg.3667

Similar proteinsi

Entry informationi

Entry nameiOPUCB_BACSU
AccessioniPrimary (citable) accession number: O34878
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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