Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoglucosamine mutase

Gene

glmM

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity). Glucosamine-1-phosphate is used for cell wall biosynthesis (Probable).UniRule annotation1 Publication

Catalytic activityi

Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei100Phosphoserine intermediate1
Metal bindingi100Magnesium; via phosphate groupUniRule annotation1
Metal bindingi240MagnesiumUniRule annotation1
Metal bindingi242MagnesiumUniRule annotation1
Metal bindingi244MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciBSUB:BSU01770-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglucosamine mutaseUniRule annotation (EC:5.4.2.10UniRule annotation)
Gene namesi
Name:glmMUniRule annotation
Synonyms:ybbT
Ordered Locus Names:BSU01770
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001478461 – 448Phosphoglucosamine mutaseAdd BLAST448

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei100PhosphoserineUniRule annotation1

Post-translational modificationi

Activated by phosphorylation.UniRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO34824
PRIDEiO34824

Expressioni

Inductioni

Constitutively expressed, part of the cdaA-cdaR-glmM-glmS operon (PubMed:23192352).1 Publication

Interactioni

Subunit structurei

Homodimer, may form a complex with CdaA.1 Publication

Protein-protein interaction databases

IntActiO34824 1 interactor.
MINTiO34824
STRINGi224308.Bsubs1_010100001008

Structurei

3D structure databases

ProteinModelPortaliO34824
SMRiO34824
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphohexose mutase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QJF Bacteria
COG1109 LUCA
HOGENOMiHOG000268678
InParanoidiO34824
KOiK03431
OMAiMFGEEYT
PhylomeDBiO34824

Family and domain databases

CDDicd05802 GlmM, 1 hit
HAMAPiMF_01554_B GlmM_B, 1 hit
InterProiView protein in InterPro
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005843 A-D-PHexomutase_C
IPR036900 A-D-PHexomutase_C_sf
IPR016066 A-D-PHexomutase_CS
IPR005841 Alpha-D-phosphohexomutase_SF
IPR006352 GlmM_bact
PfamiView protein in Pfam
PF02878 PGM_PMM_I, 1 hit
PF02879 PGM_PMM_II, 1 hit
PF02880 PGM_PMM_III, 1 hit
PF00408 PGM_PMM_IV, 1 hit
PRINTSiPR00509 PGMPMM
SUPFAMiSSF53738 SSF53738, 3 hits
SSF55957 SSF55957, 1 hit
TIGRFAMsiTIGR01455 glmM, 1 hit
PROSITEiView protein in PROSITE
PS00710 PGM_PMM, 1 hit

Sequencei

Sequence statusi: Complete.

O34824-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKYFGTDGV RGVANSELTP ELAFKVGRFG GYVLTKDKQR PKVLIGRDTR
60 70 80 90 100
ISGHMLEGAL VAGLLSIGAE VMRLGVISTP GVSYLTKAMD AEAGVMISAS
110 120 130 140 150
HNPVQDNGIK FFGGDGFKLS DEQEAEIERL MDEPEDKLPR PVGADLGLVN
160 170 180 190 200
DYFEGGQKYL QFLKQTADED FTGIHVALDC ANGATSSLAT HLFADLDADV
210 220 230 240 250
STMGTSPNGL NINDGVGSTH PEALSAFVKE KNADLGLAFD GDGDRLIAVD
260 270 280 290 300
EKGNIVDGDQ IMYICSKHLK SEGRLKDDTV VSTVMSNLGF YKALEKEGIK
310 320 330 340 350
SVQTAVGDRY VVEAMKKDGY NVGGEQSGHL IFLDYNTTGD GLLSAIMLMN
360 370 380 390 400
TLKATGKPLS ELAAEMQKFP QLLVNVRVTD KYKVEENEKV KAVISEVEKE
410 420 430 440
MNGDGRILVR PSGTEPLVRV MAEAKTKELC DEYVNRIVEV VRSEMGLE
Length:448
Mass (Da):48,433
Last modified:January 1, 1998 - v1
Checksum:iD13861BF333EFFA3
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti7T → K in BAA33070 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB006424 Genomic DNA Translation: BAA33070.1
AL009126 Genomic DNA Translation: CAB11953.1
PIRiB69745
RefSeqiNP_388058.1, NC_000964.3
WP_003234946.1, NZ_JNCM01000030.1

Genome annotation databases

EnsemblBacteriaiCAB11953; CAB11953; BSU01770
GeneIDi938632
KEGGibsu:BSU01770
PATRICifig|224308.179.peg.183

Similar proteinsi

Entry informationi

Entry nameiGLMM_BACSU
AccessioniPrimary (citable) accession number: O34824
Secondary accession number(s): O87090
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: January 1, 1998
Last modified: February 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome