Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transcriptional regulatory protein DesR

Gene

desR

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Member of the two-component regulatory system DesR/DesK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase.5 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi155 – 174H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation, Two-component regulatory system

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciBSUB:BSU19200-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein DesR
Gene namesi
Name:desR
Synonyms:yocG
Ordered Locus Names:BSU19200
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003607721 – 199Transcriptional regulatory protein DesRAdd BLAST199

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei544-aspartylphosphatePROSITE-ProRule annotation1

Post-translational modificationi

Phosphorylated by DesK.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiO34723.

Interactioni

Protein-protein interaction databases

DIPiDIP-48967N.
STRINGi224308.Bsubs1_010100010596.

Structurei

Secondary structure

1199
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 6Combined sources5
Turni7 – 10Combined sources4
Helixi12 – 21Combined sources10
Beta strandi27 – 29Combined sources3
Helixi37 – 46Combined sources10
Beta strandi49 – 54Combined sources6
Beta strandi58 – 60Combined sources3
Helixi64 – 67Combined sources4
Turni68 – 71Combined sources4
Beta strandi75 – 82Combined sources8
Helixi87 – 93Combined sources7
Beta strandi98 – 101Combined sources4
Helixi106 – 117Combined sources12
Helixi125 – 127Combined sources3
Beta strandi128 – 130Combined sources3
Helixi140 – 151Combined sources12
Helixi155 – 161Combined sources7
Helixi166 – 192Combined sources27

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4LDZX-ray2.31A/B1-199[»]
4LE0X-ray2.27A/B1-135[»]
4LE1X-ray1.95A/B1-135[»]
4LE2X-ray2.54A/B/C/D1-135[»]
ProteinModelPortaliO34723.
SMRiO34723.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 117Response regulatoryPROSITE-ProRule annotationAdd BLAST115
Domaini131 – 196HTH luxR-typePROSITE-ProRule annotationAdd BLAST66

Sequence similaritiesi

Contains 1 HTH luxR-type DNA-binding domain.PROSITE-ProRule annotation
Contains 1 response regulatory domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108S01. Bacteria.
COG2197. LUCA.
HOGENOMiHOG000034813.
InParanoidiO34723.
KOiK07693.
OMAiELMEDIY.
PhylomeDBiO34723.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiPS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O34723-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISIFIAEDQ QMLLGALGSL LNLEDDMEVV GKGTTGQDAV DFVKKRQPDV
60 70 80 90 100
CIMDIEMPGK TGLEAAEELK DTGCKIIILT TFARPGYFQR AIKAGVKGYL
110 120 130 140 150
LKDSPSEELA NAIRSVMNGK RIYAPELMED LYSEANPLTD REKEVLELVA
160 170 180 190
DGKNTKEIAQ ELSIKSGTVR NYISMILEKL EVKNRIEAIT RSKEKGWFK
Length:199
Mass (Da):22,177
Last modified:January 1, 1998 - v1
Checksum:i8D27B10320FA4974
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF027868 Genomic DNA. Translation: AAB84438.1.
AL009126 Genomic DNA. Translation: CAB13812.1.
PIRiD69901.
RefSeqiNP_389801.1. NC_000964.3.
WP_004399356.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB13812; CAB13812; BSU19200.
GeneIDi939664.
KEGGibsu:BSU19200.
PATRICi18975689. VBIBacSub10457_2035.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF027868 Genomic DNA. Translation: AAB84438.1.
AL009126 Genomic DNA. Translation: CAB13812.1.
PIRiD69901.
RefSeqiNP_389801.1. NC_000964.3.
WP_004399356.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4LDZX-ray2.31A/B1-199[»]
4LE0X-ray2.27A/B1-135[»]
4LE1X-ray1.95A/B1-135[»]
4LE2X-ray2.54A/B/C/D1-135[»]
ProteinModelPortaliO34723.
SMRiO34723.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48967N.
STRINGi224308.Bsubs1_010100010596.

Proteomic databases

PaxDbiO34723.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB13812; CAB13812; BSU19200.
GeneIDi939664.
KEGGibsu:BSU19200.
PATRICi18975689. VBIBacSub10457_2035.

Phylogenomic databases

eggNOGiENOG4108S01. Bacteria.
COG2197. LUCA.
HOGENOMiHOG000034813.
InParanoidiO34723.
KOiK07693.
OMAiELMEDIY.
PhylomeDBiO34723.

Enzyme and pathway databases

BioCyciBSUB:BSU19200-MONOMER.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiPS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDESR_BACSU
AccessioniPrimary (citable) accession number: O34723
Secondary accession number(s): Q796C7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.