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O34697 (BCEA_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Bacitracin export ATP-binding protein BceA
Gene names
Name:bceA
Synonyms:barC, ytsC
Ordered Locus Names:BSU30380
OrganismBacillus subtilis (strain 168) [Reference proteome] [HAMAP]
Taxonomic identifier224308 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length253 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Part of the ABC transporter complex BceAB (TC 3.A.1.123.5) involved in bacitracin export. Responsible for energy coupling to the transport system. Ref.3 Ref.4

Subunit structure

The complex is composed of two ATP-binding proteins (BceA) and two transmembrane proteins (BceB) Probable.

Induction

Expression is induced by bacitracin, via the two-component regulatory system BceS/BceR. Ref.3 Ref.4 Ref.5

Sequence similarities

Belongs to the ABC transporter superfamily.

Contains 1 ABC transporter domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 253253Bacitracin export ATP-binding protein BceA
PRO_0000091945

Regions

Domain4 – 243240ABC transporter
Nucleotide binding40 – 478ATP Potential

Sequences

Sequence LengthMass (Da)Tools
O34697 [UniParc].

Last modified January 1, 1998. Version 1.
Checksum: 95D28581A96627AA

FASTA25328,234
        10         20         30         40         50         60 
MVILEANKIR KSYGNKLNKQ EVLKGIDIHI EKGEFVSIMG ASGSGKTTLL NVLSSIDQVS 

        70         80         90        100        110        120 
HGTIHINGND MTAMKEKQLA EFRKQHLGFI FQDYNLLDTL TVKENILLPL SITKLSKKEA 

       130        140        150        160        170        180 
NRKFEEVAKE LGIYELRDKY PNEISGGQKQ RTSAGRAFIH DPSIIFADEP TGALDSKSAS 

       190        200        210        220        230        240 
DLLNKLSQLN QKRNATIIMV THDPVAASYC GRVIFIKDGQ MYTQLNKGGQ DRQTFFQDIM 

       250 
KTQGVLGGVQ HEH

« Hide

References

« Hide 'large scale' references
[1]"Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region."
Lapidus A., Galleron N., Sorokin A., Ehrlich S.D.
Microbiology 143:3431-3441(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[3]"YtsCD and YwoA, two independent systems that confer bacitracin resistance to Bacillus subtilis."
Bernard R., Joseph P., Guiseppi A., Chippaux M., Denizot F.
FEMS Microbiol. Lett. 228:93-97(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION, PROBABLE FUNCTION.
Strain: 168.
[4]"The BceRS two-component regulatory system induces expression of the bacitracin transporter, BceAB, in Bacillus subtilis."
Ohki R., Giyanto X., Tateno K., Masuyama W., Moriya S., Kobayashi K., Ogasawara N.
Mol. Microbiol. 49:1135-1144(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION, PROBABLE FUNCTION.
Strain: 168.
[5]"Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon."
Mascher T., Margulis N.G., Wang T., Ye R.W., Helmann J.D.
Mol. Microbiol. 50:1591-1604(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
Strain: 168 / CU1065.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF008220 Genomic DNA. Translation: AAC00255.1.
AL009126 Genomic DNA. Translation: CAB15016.1.
PIRA70001.
RefSeqNP_390916.1. NC_000964.3.

3D structure databases

ProteinModelPortalO34697.
SMRO34697. Positions 2-227.
ModBaseSearch...

Protein-protein interaction databases

STRING224308.BSU30380.

Protein family/group databases

TCDB3.A.1.134.3. ATP-binding cassette (ABC) superfamily.

Proteomic databases

PaxDbO34697.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB15016; CAB15016; BSU30380.
GeneID937246.
KEGGbsu:BSU30380.
PATRIC18977978. VBIBacSub10457_3177.

Organism-specific databases

GenoListBSU30380. [Micado]

Phylogenomic databases

eggNOGCOG1136.
KOK11631.
OMAIKDGQMY.
ProtClustDBCLSK873748.

Enzyme and pathway databases

BioCycBSUB:BSU30380-MONOMER.

Family and domain databases

InterProIPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
[Graphical view]
PfamPF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
[Graphical view]
PROSITEPS00211. ABC_TRANSPORTER_1. False negative.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBCEA_BACSU
AccessionPrimary (citable) accession number: O34697
Entry history
Integrated into UniProtKB/Swiss-Prot: February 2, 2004
Last sequence update: January 1, 1998
Last modified: May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Recent format changes

Overview of recent format changes

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents