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Protein

Uncharacterized oxidoreductase YtbE

Gene

ytbE

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei54Proton donorBy similarity1
Sitei83Lowers pKa of active site TyrBy similarity1
Binding sitei116SubstrateBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi194 – 246NADPBy similarityAdd BLAST53

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciBSUB:BSU29050-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YtbE (EC:1.-.-.-)
Gene namesi
Name:ytbE
Ordered Locus Names:BSU29050
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003606471 – 280Uncharacterized oxidoreductase YtbEAdd BLAST280

Proteomic databases

PaxDbiO34678.
PRIDEiO34678.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100015846.

Structurei

Secondary structure

1280
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 10Combined sources3
Beta strandi16 – 20Combined sources5
Helixi31 – 43Combined sources13
Beta strandi47 – 49Combined sources3
Helixi52 – 54Combined sources3
Helixi57 – 71Combined sources15
Helixi75 – 77Combined sources3
Beta strandi79 – 84Combined sources6
Helixi86 – 88Combined sources3
Helixi91 – 105Combined sources15
Beta strandi110 – 117Combined sources8
Turni120 – 122Combined sources3
Helixi123 – 135Combined sources13
Beta strandi138 – 146Combined sources9
Helixi149 – 155Combined sources7
Turni156 – 158Combined sources3
Beta strandi164 – 169Combined sources6
Helixi177 – 186Combined sources10
Beta strandi189 – 194Combined sources6
Helixi197 – 199Combined sources3
Turni200 – 203Combined sources4
Helixi205 – 213Combined sources9
Helixi218 – 228Combined sources11
Helixi240 – 247Combined sources8
Helixi256 – 263Combined sources8

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3B3DX-ray2.30A/B/C1-280[»]
ProteinModelPortaliO34678.
SMRiO34678.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO34678.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldo/keto reductase family.Curated

Phylogenomic databases

eggNOGiENOG4105CV8. Bacteria.
COG0656. LUCA.
HOGENOMiHOG000250272.
InParanoidiO34678.
OMAiQHEVGEA.
PhylomeDBiO34678.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O34678-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTHLQAKAT LHNGVEMPWF GLGVFQVEEG SELVNAVKTA IVHGYRSIDT
60 70 80 90 100
AAIYGNEAGV GEGIREGIEE AGISREDLFI TSKVWNADLG YEETLAAFET
110 120 130 140 150
SLSKLGLDYL DLYLIHWPVE GKYKEAWRAL ETLYKEGRIK AIGVSNFQIH
160 170 180 190 200
HLEDLMTAAE IKPMINQVEF HPRLTQKELI RYCQNQGIQM EAWSPLMQGQ
210 220 230 240 250
LLDHPVLADI AQTYNKSVAQ IILRWDLQHG IITIPKSTKE HRIKENASVF
260 270 280
DFELTQDDMN RIDALNENLR VGPDPDNFDF
Length:280
Mass (Da):31,768
Last modified:January 1, 1998 - v1
Checksum:iD21C6DDF199CB5D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00406.1.
AL009126 Genomic DNA. Translation: CAB14865.1.
PIRiD69988.
RefSeqiNP_390783.1. NC_000964.3.
WP_003229455.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14865; CAB14865; BSU29050.
GeneIDi937384.
KEGGibsu:BSU29050.
PATRICi18977702. VBIBacSub10457_3039.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00406.1.
AL009126 Genomic DNA. Translation: CAB14865.1.
PIRiD69988.
RefSeqiNP_390783.1. NC_000964.3.
WP_003229455.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3B3DX-ray2.30A/B/C1-280[»]
ProteinModelPortaliO34678.
SMRiO34678.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100015846.

Proteomic databases

PaxDbiO34678.
PRIDEiO34678.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14865; CAB14865; BSU29050.
GeneIDi937384.
KEGGibsu:BSU29050.
PATRICi18977702. VBIBacSub10457_3039.

Phylogenomic databases

eggNOGiENOG4105CV8. Bacteria.
COG0656. LUCA.
HOGENOMiHOG000250272.
InParanoidiO34678.
OMAiQHEVGEA.
PhylomeDBiO34678.

Enzyme and pathway databases

BioCyciBSUB:BSU29050-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO34678.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYTBE_BACSU
AccessioniPrimary (citable) accession number: O34678
Secondary accession number(s): Q795V7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: November 30, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.