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Protein

Uncharacterized oxidoreductase YtbE

Gene

ytbE

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei54 – 541Proton donorBy similarity
Sitei83 – 831Lowers pKa of active site TyrBy similarity
Binding sitei116 – 1161SubstrateBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi194 – 24653NADPBy similarityAdd
BLAST

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Enzyme and pathway databases

BioCyciBSUB:BSU29050-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized oxidoreductase YtbE (EC:1.-.-.-)
Gene namesi
Name:ytbE
Ordered Locus Names:BSU29050
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 280280Uncharacterized oxidoreductase YtbEPRO_0000360647Add
BLAST

Proteomic databases

PaxDbiO34678.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100015846.

Structurei

Secondary structure

1
280
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi8 – 103Combined sources
Beta strandi16 – 205Combined sources
Helixi31 – 4313Combined sources
Beta strandi47 – 493Combined sources
Helixi52 – 543Combined sources
Helixi57 – 7115Combined sources
Helixi75 – 773Combined sources
Beta strandi79 – 846Combined sources
Helixi86 – 883Combined sources
Helixi91 – 10515Combined sources
Beta strandi110 – 1178Combined sources
Turni120 – 1223Combined sources
Helixi123 – 13513Combined sources
Beta strandi138 – 1469Combined sources
Helixi149 – 1557Combined sources
Turni156 – 1583Combined sources
Beta strandi164 – 1696Combined sources
Helixi177 – 18610Combined sources
Beta strandi189 – 1946Combined sources
Helixi197 – 1993Combined sources
Turni200 – 2034Combined sources
Helixi205 – 2139Combined sources
Helixi218 – 22811Combined sources
Helixi240 – 2478Combined sources
Helixi256 – 2638Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3B3DX-ray2.30A/B/C1-280[»]
ProteinModelPortaliO34678.
SMRiO34678. Positions 1-280.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO34678.

Family & Domainsi

Sequence similaritiesi

Belongs to the aldo/keto reductase family.Curated

Phylogenomic databases

eggNOGiENOG4105CV8. Bacteria.
COG0656. LUCA.
HOGENOMiHOG000250272.
InParanoidiO34678.
OMAiQHEVGEA.
PhylomeDBiO34678.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O34678-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTHLQAKAT LHNGVEMPWF GLGVFQVEEG SELVNAVKTA IVHGYRSIDT
60 70 80 90 100
AAIYGNEAGV GEGIREGIEE AGISREDLFI TSKVWNADLG YEETLAAFET
110 120 130 140 150
SLSKLGLDYL DLYLIHWPVE GKYKEAWRAL ETLYKEGRIK AIGVSNFQIH
160 170 180 190 200
HLEDLMTAAE IKPMINQVEF HPRLTQKELI RYCQNQGIQM EAWSPLMQGQ
210 220 230 240 250
LLDHPVLADI AQTYNKSVAQ IILRWDLQHG IITIPKSTKE HRIKENASVF
260 270 280
DFELTQDDMN RIDALNENLR VGPDPDNFDF
Length:280
Mass (Da):31,768
Last modified:January 1, 1998 - v1
Checksum:iD21C6DDF199CB5D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00406.1.
AL009126 Genomic DNA. Translation: CAB14865.1.
PIRiD69988.
RefSeqiNP_390783.1. NC_000964.3.
WP_003229455.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14865; CAB14865; BSU29050.
GeneIDi937384.
KEGGibsu:BSU29050.
PATRICi18977702. VBIBacSub10457_3039.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF008220 Genomic DNA. Translation: AAC00406.1.
AL009126 Genomic DNA. Translation: CAB14865.1.
PIRiD69988.
RefSeqiNP_390783.1. NC_000964.3.
WP_003229455.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3B3DX-ray2.30A/B/C1-280[»]
ProteinModelPortaliO34678.
SMRiO34678. Positions 1-280.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100015846.

Proteomic databases

PaxDbiO34678.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14865; CAB14865; BSU29050.
GeneIDi937384.
KEGGibsu:BSU29050.
PATRICi18977702. VBIBacSub10457_3039.

Phylogenomic databases

eggNOGiENOG4105CV8. Bacteria.
COG0656. LUCA.
HOGENOMiHOG000250272.
InParanoidiO34678.
OMAiQHEVGEA.
PhylomeDBiO34678.

Enzyme and pathway databases

BioCyciBSUB:BSU29050-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO34678.

Family and domain databases

CDDicd06660. Aldo_ket_red. 1 hit.
Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFiPIRSF000097. AKR. 1 hit.
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
PS00063. ALDOKETO_REDUCTASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYTBE_BACSU
AccessioniPrimary (citable) accession number: O34678
Secondary accession number(s): Q795V7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.