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Protein

Putative aldehyde dehydrogenase DhaS

Gene

dhaS

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei266PROSITE-ProRule annotation1
Active sitei300PROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi244 – 249NADSequence analysis6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciBSUB:BSU19310-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase DhaSPROSITE-ProRule annotation (EC:1.2.1.3PROSITE-ProRule annotation)
Gene namesi
Name:dhaS
Ordered Locus Names:BSU19310
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Pathology & Biotechi

Disruption phenotypei

No effect on vanillin degradation.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003795091 – 495Putative aldehyde dehydrogenase DhaSAdd BLAST495

Proteomic databases

PaxDbiO34660
PRIDEiO34660

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100010661

Structurei

3D structure databases

ProteinModelPortaliO34660
SMRiO34660
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiENOG4105C26 Bacteria
COG1012 LUCA
HOGENOMiHOG000271505
InParanoidiO34660
KOiK00128
OMAiGEWVKPV
PhylomeDBiO34660

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 1 hit
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
IPR012394 Aldehyde_DH_NAD(P)
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
PIRSFiPIRSF036492 ALDH, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

O34660-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLTMQVTK RLETFLQGTK KLYIDGKFVP SASGATFDTP NPATGETLMT
60 70 80 90 100
LYEAQAADVD KAVKAARKAF DQGEWRTMSP ASRSRLMYKL ADLMEEHKTE
110 120 130 140 150
LAQLETLDNG KPINETTNGD IPLAIEHMRY YAGWCTKITG QTIPVSGAYF
160 170 180 190 200
NYTRHEPVGV VGQIIPWNFP LLMAMWKMGA ALATGCTIVL KPAEQTPLSA
210 220 230 240 250
LYLAELIDQA GFPAGVINII PGFGEDAGEA LTNHEAVDKI AFTGSTEIGK
260 270 280 290 300
KIMSTAAKSI KRVTLELGGK SPNILLPDAN LKKAIPGALN GVMFNQGQVC
310 320 330 340 350
CAGSRVFIHK DQYDEVVDEM ASYAESLRQG AGLHKDTQIG PLVSKEQHER
360 370 380 390 400
VLSYIQKGKD EGAKAVTGGS CPFEAGYFVA PTVFANVEDE MTIAKEEIFG
410 420 430 440 450
PVLTAIPYET VDEVIERANH SEYGLAAGLW TENVKQAHYI ADRLQAGTVW
460 470 480 490
VNCYNVFDAA SPFGGYKQSG LGREMGSYAL DNYTEVKSVW VNLED
Length:495
Mass (Da):53,882
Last modified:January 1, 1998 - v1
Checksum:i24EBC782F47034A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF027868 Genomic DNA Translation: AAB84440.1
AL009126 Genomic DNA Translation: CAB13823.1
PIRiH69614
RefSeqiNP_389813.1, NC_000964.3
WP_004399332.1, NZ_JNCM01000036.1

Genome annotation databases

EnsemblBacteriaiCAB13823; CAB13823; BSU19310
GeneIDi939963
KEGGibsu:BSU19310
PATRICifig|224308.179.peg.2112

Similar proteinsi

Entry informationi

Entry nameiALDH4_BACSU
AccessioniPrimary (citable) accession number: O34660
Secondary accession number(s): Q796C4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 7, 2009
Last sequence update: January 1, 1998
Last modified: April 25, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health