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Protein

HTH-type transcriptional regulator LmrA

Gene

lmrA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as repressor of the lincomycin-resistance (lmrAB) and yxaGH operons.3 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi27 – 46H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciBSUB:BSU02680-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator LmrA
Gene namesi
Name:lmrA
Synonyms:yccB
Ordered Locus Names:BSU02680
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003607091 – 188HTH-type transcriptional regulator LmrAAdd BLAST188

Proteomic databases

PaxDbiO34619.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100001488.

Structurei

3D structure databases

ProteinModelPortaliO34619.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 64HTH tetR-typePROSITE-ProRule annotationAdd BLAST61

Sequence similaritiesi

Contains 1 HTH tetR-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105J7D. Bacteria.
ENOG4111TWN. LUCA.
HOGENOMiHOG000161263.
InParanoidiO34619.
KOiK18939.
OMAiEACHEAY.
PhylomeDBiO34619.

Family and domain databases

Gene3Di1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O34619-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYGDSREKI LSAATRLFQL QGYYGTGLNQ IIKESGAPKG SLYYHFPGGK
60 70 80 90 100
EQLAIEAVNE MKEYIRQKIA DCMEACTDPA EGIQAFLKEL SCQFSCTEDI
110 120 130 140 150
EGLPVGLLAA ETSLKSEPLR EACHEAYKEW ASVYEEKLRQ TGCSESRAKE
160 170 180
ASTVVNAMIE GGILLSLTAK NSTPLLHISS CIPDLLKR
Length:188
Mass (Da):20,663
Last modified:January 1, 1998 - v1
Checksum:i2FE6827325231A5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000617 Genomic DNA. Translation: BAA22229.1.
AL009126 Genomic DNA. Translation: CAB12062.1.
PIRiD69652.
RefSeqiNP_388150.1. NC_000964.3.
WP_003246449.1. NZ_JNCM01000030.1.

Genome annotation databases

EnsemblBacteriaiCAB12062; CAB12062; BSU02680.
GeneIDi938385.
KEGGibsu:BSU02680.
PATRICi18972095. VBIBacSub10457_0276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000617 Genomic DNA. Translation: BAA22229.1.
AL009126 Genomic DNA. Translation: CAB12062.1.
PIRiD69652.
RefSeqiNP_388150.1. NC_000964.3.
WP_003246449.1. NZ_JNCM01000030.1.

3D structure databases

ProteinModelPortaliO34619.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100001488.

Proteomic databases

PaxDbiO34619.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12062; CAB12062; BSU02680.
GeneIDi938385.
KEGGibsu:BSU02680.
PATRICi18972095. VBIBacSub10457_0276.

Phylogenomic databases

eggNOGiENOG4105J7D. Bacteria.
ENOG4111TWN. LUCA.
HOGENOMiHOG000161263.
InParanoidiO34619.
KOiK18939.
OMAiEACHEAY.
PhylomeDBiO34619.

Enzyme and pathway databases

BioCyciBSUB:BSU02680-MONOMER.

Family and domain databases

Gene3Di1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLMRA_BACSU
AccessioniPrimary (citable) accession number: O34619
Secondary accession number(s): Q797R9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: October 5, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.